Sex-biased gene expression in nutrient-sensing pathways. [PDF]
Proc Biol Sci, 2023 Differences in lifespan between males and females are found across many taxa and may be determined, at least in part, by differential responses to diet.
Bennett-Keki S +4 more
europepmc +6 more sources
Evolution of sex-biased gene expression in a dioecious plant [PDF]
Nature Plants, 2016 Separate sexes and sex-biased gene expression have repeatedly evolved in animals and plants, but the underlying changes in gene expression remain unknown.
Marais, Gabriel, A.B. +16 more
core +5 more sources
Sex-Specific Selection and Sex-Biased Gene Expression in Humans and Flies. [PDF]
PLoS Genetics, 2016 Sexual dimorphism results from sex-biased gene expression, which evolves when selection acts differently on males and females. While there is an intimate connection between sex-biased gene expression and sex-specific selection, few empirical studies have
Changde Cheng, Mark Kirkpatrick
doaj +2 more sources
Sex-biased gene expression and recent sex chromosome turnover. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2021 Abstract Cichlids are well known for their propensity to radiate generating arrays of morphologically and ecologically diverse species in short evolutionary time. Following this rapid evolutionary pace, cichlids show high rates of sex chromosome turnover. We here studied the evolution of sex-biased gene (SBG) expression in 14 recently
Lichilín N, El Taher A, Böhne A.
europepmc +5 more sources
Large scale gene expression meta-analysis reveals tissue-specific, sex-biased gene expression in humans [PDF]
Frontiers in Genetics, 2016 The severity and prevalence of many diseases are known to differ between the sexes. Organ specific sex-biased gene expression may underpin these and other sexually dimorphic traits.
Benjamin Mayne +12 more
doaj +4 more sources
Gene Duplication and the Genome Distribution of Sex-Biased Genes [PDF]
International Journal of Evolutionary Biology, 2011 In species that have two sexes, a single genome encodes two morphs, as each sex can be thought of as a distinct morph. This means that the same set of genes are differentially expressed in the different sexes.
Susana Domingues +2 more
core +4 more sources
Relationship between sex biases in gene expression and sex biases in autism and Alzheimer’s disease
Biology of Sex DifferencesBackground Sex differences in the brain may play an important role in sex-differential prevalence of neuropsychiatric conditions. Methods In order to understand the transcriptional basis of sex differences, we analyzed multiple, large-scale, human ...
Stuart B. Fass +8 more
doaj +3 more sources
Sex-biased and parental allele-specific gene regulation by KDM6A [PDF]
Biology of Sex Differences, 2022 BACKGROUND: KDM6A is a demethylase encoded by a gene with female-biased expression due to escape from X inactivation. Its main role is to facilitate gene expression through removal of the repressive H3K27me3 mark, with evidence of some additional histone
Fang, He +14 more
core +6 more sources
Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals. [PDF]
Biol Sex Differ, 2023 Background: Mammalian gonadal sex is determined by the presence or absence of a Y chromosome and the subsequent production of sex hormones contributes to secondary sexual differentiation.
Richardson V, Engel N, Kulathinal RJ.
europepmc +3 more sources
Phylogenetic inconsistency caused by ancient sex-biased gene migration. [PDF]
PLoS ONE, 2011 Inferences of ancient sex-biased migration patterns using sex-linked genetic markers are usually difficult because of a stochastic process of allele fixation.
Naoki Osada
doaj +4 more sources