Results 131 to 140 of about 6,189,888 (256)

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Decoding Sex-Biased Gene Expression Patterns in Heart Disease [PDF]

Mayo Clinic Proceedings, 2020
Satsuki, Yamada, Andre, Terzic
openaire   +2 more sources

MAP7D2 is a brain expressing X-linked maternal imprinted gene in humans [PDF]

, 2011
Increasing evidence suggests imprinted genes influence mouse and human behaviors and cognitive functions. Unlike autosomal imprinted genes, X-linked imprinted genes are expressed in a sex-dependent manner because of male hemizygosity.
Yo Niida, Akihiro Yachie
core  

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Tissue Specificity of Sex-biased Gene Expression and the Development of Sexual Dimorphism [PDF]

, 2018
One prominent form of phenotypic diversity in nature is the dramatic difference between males and females within a single species. A central genetic obstacle which must be overcome is that two distinct phenotypes must be produced from a single, shared ...
Chung, Albert K
core  

Model for X-linked trans-regulation of sex-biased gene expression.

, 2015
Black bars represent genes, coloured bars trans-factors, length of arrows from genes indicate amount of gene expression, and colours of arrows match the colour of the trans-factor that regulates the expression.
Rebecca Dean (109545), Urban Friberg (209170), Michael Stocks (587988), Björn Rogell (697529)   +3 more
core   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Reference genes to study the sex-biased expression of genes regulating Drosophila metabolism

Scientific Reports
AbstractSex is an important variable in biology. Notable differences have been observed between male and female Drosophila in regulation of metabolism, in response to nutritional challenges, and in phenotypes relevant for obesity and metabolic disorders.
De Groef, Sofie, Lopes, Melanie Ribeiro, Winant, Mattias, Rosschaert, Emily, Wilms, Tom, Bolckmans, Lenz, Calevro, Federica, Callaerts, Patrick   +7 more
openaire   +6 more sources

Positive selection and relaxed purifying selection contribute to rapid evolution of male-biased genes in a dioecious flowering plant

eLife
Sex-biased genes offer insights into the evolution of sexual dimorphism. Sex-biased genes, especially those with male bias, show elevated evolutionary rates of protein sequences driven by positive selection and relaxed purifying selection in animals ...
Lei Zhao, Wei Zhou, Jun He, De-Zhu Li, Hong-Tao Li   +4 more
doaj   +1 more source

General clustering of sex-biased gene expression depending on their “regulation of gene expression” functional category.

, 2016
male-biaises are represented in blue, female-biaises in pink and non-significant differences (Padj>0.05) in black. Three stages are considered: (a) cercariae, (b) schistosomula s#2 and (c) adults.
Marion A. L. Picard (787314), David Roquis (496526), Conor R. Caffrey (113916), Eve Toulza (48148), Christoph Grunau (269384), David Duval (178941), Thavy Long (154323), Jean-François Allienne (843746), Nathalie Arancibia (696247), Marine Rohmer (3139818), Jérôme Boissier (183774), Sabine Nidelet (3139821), Céline Cosseau (269408)   +12 more
core   +1 more source