Results 61 to 70 of about 1,582,592 (296)

Kcne4 deletion sex- and age-specifically impairs cardiac repolarization in mice. [PDF]

, 2015
Myocardial repolarization capacity varies with sex, age, and pathology; the molecular basis for this variation is incompletely understood. Here, we show that the transcript for KCNE4, a voltage-gated potassium (Kv) channel β subunit associated with human
Abbott, Geoffrey W, Crump, Shawn M, Goldstein, Steve AN, Hu, Zhaoyang, Kant, Ritu, Levy, Daniel I   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Efficacy of Ethephon Doses on Vegetative and Reproductive Attributes of Watermelon [(Citrullus lanatus (Thunb.) Matsum. & Nakai]

Turkish Journal of Agriculture: Food Science and Technology
Watermelon is a widely cultivated cucurbitaceous crop with economic and dietary significance. The plant's ability to reproduce effectively relies on the harmonious growth and maturation of both its male and female flowers.
Ashish Pangeni, Sandip Kathayat, Pankaj Karki Dholi, Sujan Khanal, Garima Parajuli, Bharat Bimarsa   +5 more
doaj   +1 more source

Sex-Specific Differences in MicroRNA Expression During Human Fetal Lung Development

Frontiers in Genetics, 2022
Background: Sex-specific differences in fetal lung maturation have been well described; however, little is known about the sex-specific differences in microRNA (miRNA) expression during human fetal lung development. Interestingly, many adult chronic lung
Nancy W. Lin, Nancy W. Lin, Cuining Liu, Cuining Liu, Ivana V. Yang, Ivana V. Yang, Lisa A. Maier, Lisa A. Maier, Dawn L. DeMeo, Cheyret Wood, Shuyu Ye, Margaret H. Cruse, Vong L. Smith, Carrie A. Vyhlidal, Katerina Kechris, Sunita Sharma   +15 more
doaj   +1 more source

MAP7D2 is a brain expressing X-linked maternal imprinted gene in humans [PDF]

, 2011
Increasing evidence suggests imprinted genes influence mouse and human behaviors and cognitive functions. Unlike autosomal imprinted genes, X-linked imprinted genes are expressed in a sex-dependent manner because of male hemizygosity.
Akihiro Yachie, Yo Niida
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The Differences Between Products Of Gene Expression In Male, Female And Hermaphrodite Cucumber Floral Buds (Cucumis Sativus L.) [PDF]

, 2011
Cucumber is a species in which sex expression has been extensively studied. Sexual differentiation is controlled by genotypic and environmental factors.
Ewa Siedlecka, Magdalena Pawelkowicz, Zbigniew Przybecki   +2 more
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

6-Benzylaminopurine (BAP) and Methyl Jasmonate (MeJa) Affect Sex Expression, Flowering Time and Flowering Intensity in Cultivated Yam Dioscorea rotundata (Poir.)

Applied Biosciences
Cultivated yam (Dioscorea rotundata) is a staple tuber crop in West Africa which is mainly vegetatively propagated. Although the majority of yam cultivars flower, the control of their sexual reproduction remains largely unknown despite its importance for
Narcisse Denadi, Aline Vanhove, Jeanne Zoundjihékpon, Christophe Gandonou, Muriel Quinet   +4 more
doaj   +1 more source

Recent sex chromosome divergence despite ancient dioecy in the willow Salix viminalis. [PDF]

, 2017
Sex chromosomes can evolve when recombination is halted between a pair of chromosomes, and this can lead to degeneration of the sex-limited chromosome.
Berlin, S., Liu Conze, L., Mank, J.E., Pucholt, P., Wright, A.E.   +4 more
core   +2 more sources