Results 81 to 90 of about 5,225,716 (254)

DNA marker-assisted sex conversion in elite papaya genotype (Carica papaya L.)

Crop Breeding and Applied Biotechnology, 2007
Papaya is a genetically narrow-based crop, with few genetically distinct cultivars available for planting. This study aimed at the sex conversion of genotype “Cariflora', from the dioecious to the gynoecious - andromonoecious stage, by means of RAPD ...
Messias Gonzaga Pereira, Francisco Filho da Silva, Wellington Ferreira Campos, Pedro Corrêa Damasceno Junior, Telma Nair Santana Pereira, Gonçalo Apolinário de Souza Filho, Helaine Christine Cancela Ramos, Alexandre Pio Viana, Geraldo Antônio Ferreguetti   +8 more
doaj  

Independent stratum formation on the avian sex chromosomes reveals inter-chromosomal gene conversion and predominance of purifying selection on the w chromosome [PDF]

, 2014
We used a comparative approach spanning three species and 90 million years to study the evolutionary history of the avian sex chromosomes. Using whole transcriptomes, we assembled the largest cross-species dataset of W-linked coding content to date.
Wright, Alison E, Harrison, Peter W, Mank, JE, Wright, AE, Montgomery, SH, Mank, Judith E, Pointer, Marie A, Harrison, PW, Pointer, MA, Montgomery, Stephen H   +9 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Somatic sex-specific transcriptome differences in Drosophila revealed by whole transcriptome sequencing

BMC Genomics, 2011
Background Understanding animal development and physiology at a molecular-biological level has been advanced by the ability to determine at high resolution the repertoire of mRNA molecules by whole transcriptome resequencing. This includes the ability to
Arbeitman Michelle N, Nuzhdin Sergey V, Dunham Joseph P, Chang Peter L   +3 more
doaj   +1 more source

Cape Town talks about sex workers [PDF]

, 2000
On Monday 25 September,, as- part of the One City Festival, the Black Arts Collective hosted a debate about sex work. Natasha from SWEAT spoke about the why the government should decriminalize sex work.
Sex Workers’ Education & Advocacy Taskforce (SWEAT)
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Relationship between sex biases in gene expression and sex biases in autism and Alzheimer’s disease

Biology of Sex Differences
Background Sex differences in the brain may play an important role in sex-differential prevalence of neuropsychiatric conditions. Methods In order to understand the transcriptional basis of sex differences, we analyzed multiple, large-scale, human ...
Stuart B. Fass, Bernard Mulvey, Rebecca Chase, Wei Yang, Din Selmanovic, Sneha M. Chaturvedi, Eric Tycksen, Lauren A. Weiss, Joseph D. Dougherty   +8 more
doaj   +1 more source

Selection shapes turnover and magnitude of sex-biased expression in Drosophila gonads

BMC Evolutionary Biology, 2019
Background Sex-biased gene expression is thought to drive the phenotypic differences in males and females in metazoans. Drosophila has served as a primary model for studying male-female differences in gene expression, and its effects on protein sequence ...
Carrie A. Whittle, Cassandra G. Extavour
doaj   +1 more source