Results 111 to 120 of about 3,086,991 (246)

POSTPRANDIAL TRIGLYCERIDE AND TESTOSTERONE IN WOMEN WITH CARDIOVASCULAR DISEASES

The Iraqi Journal of Medical Sciences, 2016
Background:High androgen levels may increase cardiovascular disease (CVD) risk in women through adverse effects on lipids, blood pressure, and glucose metabolism. Lipid abnormalitiesare often found in women with CVD.
Shaymaa Z. Al-Saedi, Ghassan A. Al-Shamma, Hashim M. Hashim   +2 more
doaj   +4 more sources

Preclinical Target Animal Safety Evaluation of Veterinary Monoclonal Antibodies: Principles, Methods, and Interpretation

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Monoclonal antibodies (mAbs) represent a rapidly expanding pharmaceutical class in veterinary medicine, with several products now authorized for use in dogs and cats. Limited published articles and veterinarian exposure to the principles of drug development present challenges in interpreting published safety evaluations that inform product ...
Adam Werts, Matthew Kuhn, Lauren Bessey, Alicia Braxton Hickman, Emily Chory, John Mitchell, Kirby Pasloske   +6 more
wiley   +1 more source

Sex hormone-binding globulin levels predict insulin sensitivity, disposition index, and cardiovascular risk during puberty

, 2009
Early puberty is associated with increased risk of subsequent cardiovascular disease. Low sex hormone-binding globulin (SHBG) levels are a feature of early puberty and of conditions associated with increased cardiovascular risk.
Aksglaede, Lise, Munch-Andersen, Thor, Petersen, Joergen Holm, Juul, Anders, Aachmann-Andersen, Niels Jacob, Hilsted, Linda, Sørensen, Kaspar, Helge, Jørn Wulff   +7 more
core   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

ASSOCATION OF SERUM SEX HORMONE BINDING GLOBULIN WITH TYPE 2 DIABETES MELLITUS

Pakistan Armed Forces Medical Journal, 2016
Objective: To investigate the association of circulating levels of sex hormone binding globulin with type 2 diabetes mellitus. Study Design: Case control study. Place and Duration of Study: The study was conducted at the Department of Chemical Pathology,
Mehnaz Khattak, Jawwad Anis Khan, Asma Hayat, Tariq Mahmood Ahmad   +3 more
doaj   +2 more sources

Summarizing the Experiences of Individuals Who Have Obesity or Larger Bodies Seeking Fertility Care: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Females who have larger bodies or obesity may be at an increased risk for experiencing infertility. Problematically, both weight or body size and infertility are stigmatized, harming quality of care. We conducted a scoping review to understand the lived experiences of patients who may be subjected to intersecting stigmas of weight and ...
Brooke J. Hebert, Hanna Randhawa, Virginie Blanchette, Kristi B. Adamo, Angela Alberga, Jean‐Patrice Baillargeon, Marilou Côté, Julia Craig, Ariadne Daniel, Liz Dennett, Nicola Heslehurst, Sarah Nutter, Ian Patton, Helena Piccinini‐Vallis, Ximena Ramos Salas, Katie Wadden, Taniya S. Nagpal   +16 more
wiley   +1 more source

Isoflavone supplementation reduced serum sex hormone-binding globulin concentration in postmenopausal women [PDF]

Universa Medicina, 2012
Introduction The bone loss that occurs with ageng in postmenopausal women is related to a decrease in serum levels of bioavailable estrogen and testosterone, which are mainly bound to sex hormone-binding globulin (SHBG) and albumin.
ML. Edy Parwanto, Yanti Indrawati, Herman Setiawan   +2 more
doaj  

Menopause and vascular endothelial health: Is it all about the oestrogen?

Experimental Physiology, EarlyView.
Abstract Cardiovascular disease (CVD) is a leading cause of mortality in women, and CVD risk is accelerated during the menopause transition. This acceleration has traditionally been attributed to the hallmark decline in oestradiol with menopause. However, the menopause transition is also characterized by changes in other sex hormones that exert effects
Virginia R. Nuckols, Allyson I. Schwab, Lyndsey E. DuBose, Kerrie L. Moreau, Megan M. Wenner   +4 more
wiley   +1 more source

Testosterone, sex hormone-binding globulin and risk of cardiovascular events : A report from the Outcome Reduction with an Initial Glargine Intervention trial

, 2019
Aims: Testosterone and its binding protein sex hormone-binding globulin have been associated with cardiovascular disease and dysglycaemia. However, information on the prognostic implication in patients at high cardiovascular risk with dysglycaemia is ...
Boman, Kurt,, Ryden, Lars, Mellbin, Linda G., Wang, Anne, Hess, Sibylle, Arver, Stefan, Lee, Shun Fu, Gerstein, Hertzel C.   +7 more
core   +1 more source

Exploring lifestyle management in polycystic ovary syndrome through implementation frameworks

Experimental Physiology, EarlyView.
Abstract Polyendocrine metabolic ovarian syndrome [PMOS; previously known as polycystic ovary syndrome (PCOS)] is an endocrine condition affecting 10%–13% of women of reproductive age, with cardiometabolic, reproductive and psychological features. The PMOS guidelines have established recommendations for its management, which can include pharmacological,
Margaret McGowan, Stephanie Cowan, Chau Thien Tay, Lisa J. Moran, Ashley H. Ng   +4 more
wiley   +1 more source