Results 181 to 190 of about 1,680,257 (302)

Associations between circulating sex hormones and anterior urethral stricture disease. [PDF]

Transl Androl Urol
Lozano LP, Luo Y, Gutierrez WR, Zorn AN, Breyer BN, Elliott SP, Myers JB, Vanni AJ, Erickson BA.   +8 more
europepmc   +1 more source

SCTR–Expressing Astrocyte–Serotonergic Neuron Signaling Drives Sexual Dimorphism in Depression Through KAT7/H4ac–Foxc2 Epigenetic Axis in an AMPK‐Dependent Manner

Advanced Science, EarlyView.
Astrocytic SCTR modulates depressive‐related phenotypes via AMPKα1, whereas lowered Mt1 blunts Megalin‐dependent AMPKα2 signaling in serotonergic neurons. Diminished AMPKα2 hinders KAT7 nuclear translocation, curtails KAT7 occupancy and H4K8ac at the Foxc2 promoter, and represses Foxc2 transcription, revealing cell‐type‐specific AMPK‐linked epigenetic ...
Fantao Meng, Jing Liu, Juanjuan Dai, Min Wu, Wentao Wang, Mengdi Zhang, Shujun Jiang, Yifan Cao, Lihong Xu, Lin Du, Dan Wang, Di Zhao, Gaofeng Qin, Dong Wang, Wei Li, Chen Li   +15 more
wiley   +1 more source

Sex Hormones and Keratoconus: In Search of the Link. [PDF]

J Clin Med
Makrypoulias I, Chatziralli I, Papaconstantinou D, Panagiotopoulos K, Kandarakis SA, Petrou P, Messerschmidt-Roth A, Droutsas K.   +7 more
europepmc   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

Advanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li, Zhuoqiong Qiu, Xiaoyu Pan, Geyang Xu, Shanshan Peng, Ronghui Zhu, Qiuyang Luo, Xiaokai Fang, Xu Yao, Wei Li   +9 more
wiley   +1 more source

When CO₂ sensing fails: Protective effects of sex hormones and potential mechanisms. [PDF]

J Neuroendocrinol
Janes TA, Cardani S, Pagliardini S.
europepmc   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source

Mapping of sex hormones in the testicular vein of healthy men.

J Clin Endocrinol Metab
Hufnagel A, Frederiksen H, Albrethsen J, Johannsen TH, Juul A, Jensen RJ, Rehfeld A, Barrès R.   +7 more
europepmc   +1 more source

Effect of sex hormones, garlic and fennel extracts in layers' breeders diet on inherited offspring sex. [PDF]

PLoS One
Bardel Z, Saki AA, Mirzaie-Asl A, Zamani P.   +3 more
europepmc   +1 more source

EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2‐Mediated µ‐Opioid Receptor Internalization

Advanced Science, EarlyView.
Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng, Xiaqing Lin, Hongyu Yao, Cheng Li, Huabao Liao, Yuexin Liu, Boxu Cao, Xue‑Jun Song   +7 more
wiley   +1 more source

Editorial: Sex hormones and cardiovascular-renal health: mechanisms, consequences, and therapeutic insights. [PDF]

Front Endocrinol (Lausanne)
Kumar P, Deer E, Shawky Elsayed N.
europepmc   +1 more source