Results 41 to 50 of about 366,885 (264)
Elevated fetal steroidogenic activity in autism [PDF]
, 2014 Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor.
Abdallah, M W +9 more
core +1 more source
Advanced Sensor Research, EarlyView.A wearable capacitive eye tracker for chronic fatigue assessment is presented, utilizing cylindrically shaped capacitive sensors made of a carbon nanotube‐paper composite. By integrating a novel fatigue‐induction protocol with machine learning, the device achieves 0.75‐sensitivity and 0.73‐specificity, providing a practical alternative to existing ...
Tianyi Li +6 more
wiley +1 more source
Advanced Science, EarlyView.This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu +38 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu +13 more
wiley +1 more source
Advanced Science, EarlyView.In people with overweight or obesity, regular exercise even without weight loss or vitamin D supplementation completely prevents the usual winter decline in the vitamin D metabolite that maintains health at a cellular level, 1,25(OH)2D3, and ameliorates the decline in the vitamin D status marker 25(OH)D.
Oliver J. Perkin +11 more
wiley +1 more source
The Role of Sex and Sex Hormones in Neurodegenerative Diseases [PDF]
Endocrine Reviews, 2019 AbstractNeurodegenerative diseases (NDs) are a wide class of disorders of the central nervous system (CNS) with unknown etiology. Several factors were hypothesized to be involved in the pathogenesis of these diseases, including genetic and environmental factors.
Vegeto, Elisabetta +8 more
openaire +3 more sources
Advanced Science, EarlyView.The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi +8 more
wiley +1 more source
Sex hormones and hypertension [PDF]
, 2017 Gender has an important influence on blood pressure, with premenopausal women having a lower arterial blood pressure than age-matched men. Compared with premenopausal women, postmenopausal women have higher blood pressures, suggesting that ovarian ...
Dubey, Raghvendra K. +3 more
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Advanced Science, EarlyView.It is shown that obesity is associated with increases in hepatic METTL14 and m6A methylation of G6pc transcript. YTHDF1 and YTHDF3 bind to m6A‐marked G6pc mRNA to increase its synthesis. Hepatocyte‐specific deletion of Mettl14 decreases G6pc m6A methylation, G6pc biosynthesis, and G6pc‐mediated gluconeogenesis, alleviating glucose metabolic defects in ...
Qiantao Zheng +6 more
wiley +1 more source
Pesticide Exposure Alters Follicle-Stimulating Hormone Levels in Mexican Agricultural Workers [PDF]
, 2005 Organophosphorous pesticides (OPs) are suspected of altering reproductive function by reducing brain acetylcholinesterase activity and monoamine levels, thus impairing hypothalamic and/or pituitary endocrine functions and gonadal processes. Our objective
Baldi I +12 more
core +2 more sources