Results 51 to 60 of about 209,673 (304)

Sex steroid hormones and allergic diseases in children: a pilot birth cohort study in the Japan Environment and Children’s Study cohort

BMC Pediatrics, 2023
Background Numerous studies suggest that sex steroids might play a role in sex disparity observed in allergic diseases in adults. However, whether sex hormones influence allergic diseases in children remains unclear.
Yumiko Miyaji, Kiwako Yamamoto-Hanada, Limin Yang, Mayako Saito-Abe, Miori Sato, Hidetoshi Mezawa, Minaho Nishizato, Masayuki Ochiai, Shouichi Ohga, Masako Oda, Hiroshi Mitsubuchi, Masayuki Shimono, Reiko Suga, Nathan Mise, Makiko Sekiyama, Shoji F. Nakayama, Yukihiro Ohya, the Japan Environment and Children’s Study (JECS)   +17 more
doaj   +1 more source

The association between sex hormones and periodontitis among American adults: A cross-sectional study

Frontiers in Endocrinology, 2023
IntroductionAfter adulthood, as a person grows older, the secretion of sex hormones in the body gradually decreases, and the risk of periodontitis increases.
Xingyang Su, Kun Jin, Xianghong Zhou, Zilong Zhang, Chichen Zhang, Yifan Li, Mi Yang, Xinyi Huang, Shishi Xu, Qiang Wei, Xu Cheng, Lu Yang, Shi Qiu, Shi Qiu   +13 more
doaj   +1 more source

Prenatal versus postnatal sex steroid hormone effects on autistic traits in children at 18 to 24 months of age

, 2012
Background Studies of prenatal exposure to sex steroid hormones predict autistic traits in children at 18 to 24 and at 96 months of age. However, it is not known whether postnatal exposure to these hormones has a similar effect.
Simon Baron-Cohen, Kevin Taylor, Thomson, Lynn, O’donnell, Kieran J, Jag Ahluwalia, Bonnie Auyeung, Thomson Lynn, Hackett Gerald, Lynn Thomson, Gerald Hackett, Ahluwalia Jag, Hackett, Gerald, Ahluwalia, Jag, Baron-cohen, Simon, O’Donnell Kieran J, Auyeung Bonnie, Kieran J O’Donnell, Baron-Cohen Simon, Auyeung, Bonnie; id_orcid, Taylor, Kevin, Taylor Kevin   +20 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Relationship between sex hormones and migraine

مجلة كلية الطب, 2015
Back ground: Migraine is a common chronic episodic disabling primary headache disorder with associated Symptoms. The neuroendocrinological alterations, disorders of the hypothalamic-hypophysial axis are believed to be implicated in the pathogenesis of ...
Gheyath AlGawwam
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Reproductive hormones and sex chromosomes drive sex differences in the sleep–wake cycle

Frontiers in Neuroscience
There are well-documented gender differences in the risk and severity of sleep disorders and associated comorbidities. While fundamental sex differences in sleep regulatory mechanisms may contribute to gender disparities, biological responses to sleep ...
Micah Ralston, J. Christopher Ehlen, Ketema Paul   +2 more
doaj   +1 more source

A sex allocation cost to polyandry in a parasitoid wasp

, 2015
R.A.B. is supported by a NERC DTG studentship.The costs and benefits of polyandry are central to understanding the near-ubiquity of female multiple mating. Here, we present evidence of a novel cost of polyandry: disrupted sex allocation.
Boulton, Rebecca, Shuker, David Michael
core   +1 more source