Results 61 to 70 of about 409,329 (299)

Reproductive hormones and sex chromosomes drive sex differences in the sleep–wake cycle

Frontiers in Neuroscience
There are well-documented gender differences in the risk and severity of sleep disorders and associated comorbidities. While fundamental sex differences in sleep regulatory mechanisms may contribute to gender disparities, biological responses to sleep ...
Micah Ralston, J. Christopher Ehlen, Ketema Paul   +2 more
doaj   +1 more source

Relationship between sex hormones and migraine

مجلة كلية الطب, 2015
Back ground: Migraine is a common chronic episodic disabling primary headache disorder with associated Symptoms. The neuroendocrinological alterations, disorders of the hypothalamic-hypophysial axis are believed to be implicated in the pathogenesis of ...
Gheyath AlGawwam
doaj   +1 more source

2D:4D Suggests a Role of Prenatal Testosterone in Gender Dysphoria [PDF]

, 2020
Gender dysphoria (GD) reflects distress caused by incongruence between one’s experienced gender identity and one’s natal (assigned) gender. Previous studies suggest that high levels of prenatal testosterone (T) in natal females and low levels in natal ...
Fazeli, Nasrin, Honekopp, Johannes, Khorashad, Behzad S., Sadr, Mostafa, Talaei, Ali   +4 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Sex hormones, aging and cardiometabolic syndrome

Biology of Sex Differences, 2019
It is well documented that the metabolic syndrome predisposes patients to increased cardiovascular risk. Emerging data indicates that cardiovascular risk conferred by metabolic syndrome is highly dependent on sex and sex hormone status throughout the ...
Jessica L. Faulkner, Eric J. Belin de Chantemèle   +1 more
doaj   +1 more source

Zygoparity and sex steroid hormone profiles in bluemouth Helicolenus dactylopterus [PDF]

, 2017
Two hundred and seven individuals (103 females and 104 males) of bluemouth Helicolenus dactylopterus (Scorpaeniformes, Sebastidae), a commercially important deep-water species with an unusual reproductive strategy, from the eastern Atlantic Ocean ranging
Barcellos, Brown-Peterson, Canario, Dahle, Eldridge, Grier, Grier, Guerreiro, Howell, Hureau, Kime, Kobayashi, Liley, Matsuyama, Muñoz, Muñoz, Nagahama, Rinchard, Schulz, Scott, Sequeira, Sequeira, Sequeira, Sequeira, Shimizu, Shinomiya, Takano, Vila, Wallace, West, Wourms   +30 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Thyroid hormones correlate with resting metabolic rate, not daily energy expenditure, in two charadriiform seabirds [PDF]

, 2013
K. Woo, M. Le Vaillant, T. van Nus, and especially A. Wesphal, J. Schultner and I. Dorresteijn, assisted with field work, often under unpleasant conditions. K. Wauthier was instrumental in wrestling the gamma counter into submission. P.
Anderson, W. Gary, Elliott, Kyle H., Gaston, Anthony J., Hare, James F., Hatch, Scott A., Palace, Vince, Speakman, John R., Welcker, Jorg   +7 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The association of urinary cadmium with sex steroid hormone concentrations in a general population sample of US adult men [PDF]

, 2008
Background Studies investigating the association of cadmium and sex steroid hormones in men have been inconsistent, but previous studies were relatively small.
Andy Menke, Eliseo Guallar, Meredith S Shiels, Sabine Rohrmann, Shehzad Basaria, Nader Rifai, William G Nelson, Elizabeth A Platz, Agency for Toxic Substances and Disease Registry, S Satarug, V Verougstraete, JW Laskey, EA Zylber-Haran, X Zeng, A Apostoli, O Akinloye, HJ Mason, X Zeng, J Jurasovic, S Telisman, X Zeng, S Satarug, J Svartberg, R Tamimi, WC Chumlea, JT Bernert Jr., S Sassa, SA Lewis, LBG Gunter EW, E Pruszkowska, DC Paschal, GW Comstock, EJ Wickings, S Rinaldi, A Vermeulen, MB Martin   +35 more
core   +1 more source