Results 81 to 90 of about 209,673 (304)

Sex Bias in Asthma Prevalence and Pathogenesis

Frontiers in Immunology, 2018
Sex-related differences in asthma prevalence are well established and change through the reproductive phases of life. As children, boys have increased prevalence of asthma compared to girls.
Ruchi Shah, Dawn C. Newcomb, Dawn C. Newcomb   +2 more
doaj   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies

, 2008
Background: Sex hormones in serum have been hypothesized to influence the risk of prostate cancer. We performed a collaborative analysis of the existing worldwide epidemiologic data to examine these associations in a uniform manner and to provide more ...
Roddam, AW, Key, TJ, Holly, Jeffrey M P, Donovan, Jenny L, Allen, NE, Appleby, P, Endogenous Hormones & Prostate Cancer Collaborative, Group   +6 more
core   +1 more source

A Pilot Study on Sex Hormones and Cognition Men with Multiple Sclerosis

, 2023
Objective: The presence of sexual dysfunction in male patients further exacerbates the adverse impressions of multiple sclerosis (MS) on the quality of life. The goal of our study was to evaluate the relationship between sex hormons and disease severity,
Sibel Çekiç, Bilge Piri Çınar, Serkan Özakbaş, Önder Çinar, Ulufer Çelebi, H. Tuğrul Atasoy, Mustafa Açıkgöz, Esra Acıman Demirel, Önder Çınar   +8 more
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

CYP3A variation, premenopausal estrone levels, and breast cancer risk.

, 2012
BACKGROUND: Epidemiological studies have provided strong evidence for a role of endogenous sex steroids in the etiology of breast cancer. Our aim was to identify common variants in genes involved in sex steroid synthesis or metabolism that are associated
Gibson, Lorna J, Jones, M, Tomlinson, IP, Ross, G, Folkerd, Elizabeth, Hillier, Stephen G, Schoemaker, M, Sawyer, Elinor, Folkerd, E, Kerin, M, Ross, Gillian, Peto, Julian, Swerdlow, A, Johnson, Nichola, Tomlinson, Ian P., Coupland, Ben, Fletcher, Olivia, Haynes, Ben, Kerin, Michael J, Williamson, Jill, Schoemaker, Minouk, Coupland, B, Simpson, Gemma, Palles, Claire, Ashworth, A, Dowsett, M, Houlston, RS, Johnson, N, Swerdlow, Anthony, Jones, Michael, Chilcott-Burns, S, Dos-Santos-Silva, Isabel, Williamson, J, Broderick, P, Zvelebil, M, Dowsett, Mitch, Walker, Kate, Fletcher, O, Houlston, Richard S, Dos Santos Silva, I, Kerin, Michael, Tomczyk, K, Walker, K, Palles, C, Zvelebil, Marketa, Gibson, Lorna J., Ashworth, Alan, Tomlinson, Ian P, Tomczyk, Katarzyna, Simpson, G, Orr, Nick; id_orcid, Orr, Nick, Orr, N, Swerdlow, Anthony J, Houlston, Richard S., Peto, J, Dos Santos Silva, Isabel, Hillier, Stephen G., Haynes, B, Hillier, SG, Sawyer, E, Broderick, Peter, Chilcott-Burns, Sarah, Gibson, LJ, Walker-Springett, Kate   +64 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Sex Hormones and Competitive Bidding [PDF]

Management Science, 2012
We correlate competitive bidding and profits in symmetric independent private value first-price auctions with salivary testosterone, estradiol, progesterone, and cortisol in more than 200 subjects. Bids are significantly positively correlated and profits are significantly negatively correlated with basal salivary progesterone, but only for females who
openaire   +6 more sources

The organisational effects of adolescent gonadal hormones on behavioural development in rats

, 2015
Gonadal steroid hormones play an important role in adolescent neural and behavioural development, causing changes that can be seen throughout life. Endogenous hormones have a direct impact on behaviour in both immediate and permanent ways by acting on ...
Kulbarsh, Kyle D.
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