Subtractive hybridization identifies stem cell-associated genes in an acute myeloid leukemia with poor prognosis [PDF]
Introduction: Current prognostic markers have improved survival prediction, however, it has not advanced treatment strategies. Gene expression profiling may identify biological markers suitable as therapeutic targets.
Abdullah, Maha+4 more
core
Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms
Mario Cazzola+2 more
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The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia [PDF]
Aymerich, Marta+12 more
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Design of SF3B1 subunit modulators of the SF3B spliceosome complex
The subject of this dissertation is the search for new therapeutic strategies for pancreatic cancer and aims to implement a Drug Discovery process for the rational design and synthesis of molecules active in the modulation of pathways related to the regulation of pre-mRNA splicing process.
openaire +3 more sources
SF3B1 and EIF1AX mutations in uveal melanoma: a protective factor, or not?
Emine Kılıç+6 more
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Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers [PDF]
Samar Alsafadi+11 more
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Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations [PDF]
Abigael Cheruiyot+18 more
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P735: THE ROLE OF SF3B1 MUTATIONS IN MYELODYSPLASTIC SYNDROMES
S. Huber+8 more
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A reduced panel of eight genes (ATM, SF3B1, NOTCH1, BIRC3, XPO1, MYD88, TNFAIP3, and TP53) as an estimator of the tumor mutational burden in chronic lymphocytic leukemia [PDF]
Jasmine Chauzeix+6 more
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