Results 61 to 70 of about 8,554 (295)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Measures of de facto employment protection legislation
Management, 2019 Research Question: The aim of this paper is to construct a numerical measure of EPL which takes into consideration the implementation of legislation and employment structure.
Maja Jandric
doaj +1 more source
Problem of shadow employment in the context of the labour market structural transformation
Skhid, 2017 У статті досліджується сучасна проблема тіньової зайнятості в контексті структурних трансформацій ринку праці. В ході дослідження встановлено основні прояви, причини виникнення (економічні, інституційні, фінансові та соціальні) та наслідки поширення тіньової зайнятості на державному рівні, на рівні підприємства та індивіда.
Shaulska, Larysa, Yakymova, Nataliia
openaire +3 more sources
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Underground Economy in Croatia [PDF]
Financial Theory and Practice, 2009 The subject of this paper is to estimate the size of underground economy in the period 2001-2007 using labour approach. Two types of data are used: administrative and survey. The main questions are: How did the activity rates move?
Marija Švec
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The Shadow Economy and Shadow Economy Labor Force: What Do We (Not) Know? [PDF]
In this paper the main focus lies on the development and the size of the shadow economy and of undeclared work (or shadow economy labor force) in OECD, developing and transition countries.
Schneider, Friedrich
core
STRATEGIC ORIENTARIES OF LEGALIZATION OF THE ECONOMY OF UKRAINE: ECONOMIC AND LEGAL ASPECTS
Фінансово-кредитна діяльність: проблеми теорії та практики, 2019 The processes of globalization and integration of economy ofUkraineto outer economic space provoke an origin in the country of a number of the crisis phenomena and destabilizing factors that negatively influence on socio-economic development of country.
M. M. Blikhar +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Economic impacts of landslides and floods on a road network
Acta Universitatis Carolinae Geographica, 2019 Even in the absence of serious injuries and fatalities, landslide and flood events can have significant socio-economic impacts. These include the severance of access to and from relatively remote communities for services and markets for goods; employment,
Mike G. Winter +3 more
doaj +1 more source