Results 61 to 70 of about 1,129,834 (295)

Economic impacts of landslides and floods on a road network

open access: yesActa Universitatis Carolinae Geographica, 2019
Even in the absence of serious injuries and fatalities, landslide and flood events can have significant socio-economic impacts. These include the severance of access to and from relatively remote communities for services and markets for goods; employment,
Mike G. Winter   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

STRATEGIC ORIENTARIES OF LEGALIZATION OF THE ECONOMY OF UKRAINE: ECONOMIC AND LEGAL ASPECTS

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики, 2019
The processes of globalization and integration of economy ofUkraineto outer economic space provoke an origin in the country of a number of the crisis phenomena and destabilizing factors that negatively influence on socio-economic development of country.
M. M. Blikhar   +3 more
doaj   +1 more source

Problem of shadow employment in the context of the labour market structural transformation

open access: yesSkhid, 2017
У статті досліджується сучасна проблема тіньової зайнятості в контексті структурних трансформацій ринку праці. В ході дослідження встановлено основні прояви, причини виникнення (економічні, інституційні, фінансові та соціальні) та наслідки поширення тіньової зайнятості на державному рівні, на рівні підприємства та індивіда.
Shaulska, Larysa, Yakymova, Nataliia
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The German labour markets: the case for more flexibility

open access: yesNotas Económicas, 2016
A framework of different labour market segments is introduced to describe the stylised facts of the German labour market. Two processes, the outsourcing of production to Middle and Eastern Europe and the transfer of jobs to the shadow economy, are ...
Peter Rühmann
doaj   +1 more source

Informal population employment as a factor of shadowing and economic danger

open access: yesSocio-Economic Research Bulletin, 2020
The article investigates the current trends of informal labor market development in Ukraine during 2016–2018, based on a synthesis of statistical data. The object of study is informal employment, which acts as a factor of economic danger for the country as a whole and its business entities.
openaire   +3 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Impact of the Shadow Economy on Tax Buoyancy in Central Java

open access: yesEconomics Development Analysis Journal
Taxation plays a strategic role as the primary source of government revenue, supporting fiscal stability and sustainable economic growth. In this context, tax buoyancy serves as an important indicator for evaluating the responsiveness of tax revenues to
Fazriel Alfathan, Agus Arifin
doaj   +1 more source

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