Results 61 to 70 of about 18,161 (258)

Construction and optimization of baicalein synthesis pathway from phenylalanine in Saccharomyces cerevisiae [PDF]

Zhongguo niangzao
In order to efficiently prepare baicalein using synthetic biology techniques, a synthesis pathway of baicalein was constructed based on the synthetic chassis cell Ch-9 from Saccharomyces cerevisiae, which synthesizes chrysin.
WANG Shun, WANG Jian, WANG Fangyi, YU Xiaojie, JIANG Huifeng, HE Ruyi, TIAN Yu, LIU Zhiguo
doaj   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Production of Arachidonic Acid by Mortierella alpina I49-N18

Food Technology and Biotechnology, 2002
Arachidonic acid (AA), an essential fatty acid in human body, fermented by Mortierella alpina I49-N18 was investigated in a shake-flask, and a 50-ton fermentor.
Ji Wang, Yun Shang, Guohong Gong, Jianming Yao, Zengling Yu, Chengling Yuan   +5 more
doaj  

Studies on Log Po/w of Quinoxaline di-N-Oxides: A Comparison of RP-HPLC Experimental and Predictive Approaches

Molecules, 2011
As reported in our previous papers, a series of quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives were synthesized and studied as anti-tuberculosis agents. Here, the capability of the shake-flask method was studied and the retention time (expressed as
James A. Platts, Antonio Monge, Ignacio Aldana, Mauro Ravera, Enrique Torres, Silvia Pérez-Silanes, Elisabetta Gabano, Elsa Moreno   +7 more
doaj   +1 more source

Modeling bikaverin production by Fusarium oxysporum CCT7620 in shake flask cultures

Bioresources and Bioprocessing, 2020
Bikaverin is a fungal red pigment that presents antimicrobial and antitumor activities. Therefore, this substance could be used as an alternative additive in the food and pharmaceutical industries.
Marcela Colombo dos Santos, Mayra de Lima Mendonça, Juliano Lemos Bicas   +2 more
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Transparent UV‐Curable Self‐Sanitizing Coatings Applicable to Diverse Surfaces and High‐Touch Screens to Mitigate Deadly Pathogen Transmission

Advanced Functional Materials, EarlyView.
Development of a transparent, self‐sanitizing antimicrobial coating technology applicable to a wide range of materials and surfaces‐including touchscreens, transparent substrates, and metal, plastic, and glass‐regardless of pathogen type. The spray‐coated, UV‐cross‐linked imidazole‐based quaternary ammonium chloride materials provide broad‐spectrum ...
Surjith Kumaran, Sumin Han, Euna Oh, Chunghee Jo, Hyerin Shin, Dae‐Hong Ko, Hyo‐Jick Choi   +6 more
wiley   +1 more source

Sustainable Catalyst‐Free PLG Networks: Recyclability, Biodegradability, and Functional Performance

Advanced Functional Materials, EarlyView.
A catalyst‐additive free covalent adaptable network is developed from star‐shaped poly(lactide‐co‐glycolide) cross‐linked with pyromellitic dianhydride, enabling internal carboxylic acid‐driven transesterification. The resulting biodegradable network exhibits mechanical robustness (Young's modulus ≈1.6 GPa), complete recyclability, rapid biodegradation
Lars Schwarzer, Emilia Fulajtar, Seema Agarwal   +2 more
wiley   +1 more source

Optimization and scale-up of fermentation of glucansucrase and branched glucan by Pediococcus pentosaceus CRAG3 using Taguchi methodology in bioreactor [PDF]

Journal of BioScience and Biotechnology, 2012
The present investigation focuses on screening and optimization of media components to enhance glucansucrase and glucan production by Pediococcus pentosaceus CRAG3 at shake-flask and bioreactor level using Taguchi orthogonal array design.
RISHIKESH SHUKLA, ARUN GOYAL
doaj  

Equilibrium solubility using shake-flask method of JM-20: a synthetic molecule with neuroprotective action [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2020
Context: Drug solubility is one of the most important physicochemical properties for the development of new pharmaceutical products, which, in our study, is a new synthetic molecule, which has been shown to have a potential neuroprotective effect in rat.
Luis O. Martínez Álvarez, Pedro L. Alejo Cisneros, Rionaldo Forte Mesa, Livania Quiñones Hinojosa, Abel Mondelo Rodríguez, Lisandra García Borges, Hugo Guerra Menéndez, Ángela Tuero Iglesias, Estael Ochoa Rodríguez, Miguel A. Cabrera Pérez   +9 more
doaj