The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Influence of the shape on the consumers perception of the packaging attributes
Packaging for fast moving consumer goods (FMCG) demands constant attention in order to stay competitive in modern dynamic markets. FMCG consumers do not think about the purchasing product until they enter the place of purchase. This emphasizes importance
Gojko Vladić +4 more
doaj
Multi-objective design optimisation of a 3D-rail stamping process using a robust multi-objective optimisation platform (RMOP) [PDF]
The paper investigates the multi-objective design optimisation of a stamping process to control the final shape and the final quality using advanced high strength steels. The design problem of the stamping process is formulated to minimise the difference
Coma Company, Martí +4 more
core +1 more source
Shaped Hierarchical Architectural Design
AbstractArchitectural design of software systems deals with high level configuration structuring. Checking that a system belongs to a software architecture style (or shape) implies that the architecture is an instance of a structurally defined class.
Hirsch, Dan, Montanari, Ugo
openaire +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Numerical study of different shape design of piston bowl for diesel engine combustion in a light duty single-cylinder engine. [PDF]
Deresso H +3 more
europepmc +1 more source
Hybrid Evolutionary Shape Manipulation for Efficient Hull Form Design Optimisation [PDF]
‘Eco-friendly shipping’ and fuel efficiency are gaining much attention in the maritime industry due to increasingly stringent environmental regulations and volatile fuel prices.
Goh, Cindy, Hock, Joo, Li, Yun
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
This study compares fashion design processes involving shape memory textiles (SMTs) compared to ones involving conventional textiles (CTs). The primary objectives were to identify barriers to the adoption of SMTs in the fashion industry from designers ...
Shin Young Jang, Chahong Chung, Jisoo Ha
doaj +1 more source
A Product Shape Design and Evaluation Model Based on Morphology Preference and Macroscopic Shape Information. [PDF]
Lu P, Hsiao SW, Wu F.
europepmc +1 more source

