Results 91 to 100 of about 974,120 (307)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Generalising knowledge and matching patterns is a basic human trait in re-using past experiences. We often cluster (group) knowledge of similar attributes as a process of learning and or aid to manage the complexity and re-use of experiential knowledge ...
Duffy, Alex H.B. +2 more
core
Computer-Aided Conceptual Design Through TRIZ-based Manipulation of Topological Optimizations [PDF]
Organised by: Cranfield UniversityIn a recent project the authors proposed the adoption of Optimization Systems [1] as a bridging element between Computer-Aided Innovation (CAI) and PLM to identify geometrical contradictions [2], a particular case of ...
Cascini, G. +3 more
core
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Numerical study of different shape design of piston bowl for diesel engine combustion in a light duty single-cylinder engine. [PDF]
Deresso H +3 more
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The use of early design tools in engineering processes : a comparative case study [PDF]
Nowadays, product design is increasingly complex: not only must it answer customer needs through complex functions; it must also ensure traceability throughout the design process, keeping in mind that standards and stringent regulations must be complied ...
AOUSSAT, Améziane +4 more
core
This study compares fashion design processes involving shape memory textiles (SMTs) compared to ones involving conventional textiles (CTs). The primary objectives were to identify barriers to the adoption of SMTs in the fashion industry from designers ...
Shin Young Jang, Chahong Chung, Jisoo Ha
doaj +1 more source
A Product Shape Design and Evaluation Model Based on Morphology Preference and Macroscopic Shape Information. [PDF]
Lu P, Hsiao SW, Wu F.
europepmc +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source

