Results 101 to 110 of about 6,626,969 (302)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Shape Machine and Architecture Theory
Presented as part of the Shape Machine Symposium on April 11, 2019 at 11:30 a.m. in theJohn & Joyce Caddell Building, Flex Space.Heather Ligler is an architect and design researcher interested in how generative and parametric design both provide a new ...
Ligler, Heather
core
Robust Rigid Shape Registration Method Using a Level Set Formulation
This paper presents a fast algorithm for robust registration of shapes implicitly represented by signed distance functions(SDF). The proposed algorithm aims to recover the transformation parameters( scaling, rotation, and translation) by minimizing the ...
Nixon, Mark +2 more
core +2 more sources
The optimal combination of size and shape parameters for classifying structural elements with the lowest percentage error is determined. For this purpose, logical sequences and a series of micrographs of tissues of the pumpkin Cucurbita pepo L.
Jimy Frank Oblitas-Cruz +2 more
doaj +1 more source
The shape parameters of coal and gangue particles derived from 3D scanning. [PDF]
Yang D +5 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
A framework for mutational signature analysis based on DNA shape parameters. [PDF]
Karolak A, Levatić J, Supek F.
europepmc +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Interactive Introduction to Shape Machine
Presented as part of the Shape Machine Symposium on April 11, 2019 at 9:10 a.m. in the John & Joyce Caddell Building, Flex Space.Athanassios (Thanos) Economou is Professor in the College of Design at Georgia Institute of Technology.
Economou, Athanassios +1 more
core
One-Sided Confidence Interval Estimation for Weibull Shape and Scale Parameters
In this paper, we consider the problem of one-sided conditional and unconditional interval estimation for the scale and shape parameters in a two-parameter Weibull model. The statistical inference is based upon the pivots advocated in Bain and Engelhardt,
Smail Mahdi
doaj +1 more source

