Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Partially Regular Microreliefs Formed by Rotation
Construction MaterialsA new scheme for forming partially regular microreliefs by rotational rolling is proposed. A new transcendental curve-shaped, partially regular microrelief (of a trochoid type) is discussed; the shape and geometric parameters of its grooves are ...
Volodymyr Dzyura +3 more
doaj +1 more source
Incremental value of left ventricular shape parameters measured by gated SPECT MPI in predicting the super-response to CRT. [PDF]
J Nucl Cardiol, 2022 He Z +5 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Parametric finite-element studies on the effect of tool shape in friction stir welding
, 2010 The success of the Friction Stir Welding (FSW) process, and the weld quality produced, depends significantly on the design of the welding tool. In this paper the effect of variation in various tool geometry parameters on FSW process outcomes, during the ...
D Mackenzie +5 more
core +1 more source
Immediate Effects of Myofascial Release on the Thoracolumbar Fascia and Osteopathic Treatment for Acute Low Back Pain on Spine Shape Parameters: A Randomized, Placebo-Controlled Trial. [PDF]
Life (Basel), 2021 Brandl A, Egner C, Schleip R.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Shape Preserving Data Interpolation Using Rational Cubic Ball Functions
Journal of Applied Mathematics, 2015 A smooth curve interpolation scheme for positive, monotone, and convex data is developed. This scheme uses rational cubic Ball representation with four shape parameters in its description. Conditions of two shape parameters are derived in such a way that
Ayser Nasir Hassan Tahat +2 more
doaj +1 more source
Comment on Brandl et al. Immediate Effects of Myofascial Release on the Thoracolumbar Fascia and Osteopathic Treatment for Acute Low Back Pain on Spine Shape Parameters: A Randomized, Placebo-Controlled Trial. Life 2021, 11, 845. [PDF]
Life (Basel), 2022 Kudus AL.
europepmc +1 more source