Results 221 to 230 of about 586,736 (276)

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

Biomechanics of Tooth-Supported Fixed Dental Prostheses: Material Systems, Connector Design, Retainer Design, and Abutment Stress Distribution-A Systematic Review of In Vitro and Finite Element Evidence. [PDF]

open access: yesMaterials (Basel)
Babiuc I   +11 more
europepmc   +1 more source

Perforated shear connectors

Steel and Composite Structures, 2002
Perforated shear connectors currently used in composite steel and concrete structures are described and evaluated. Modifications of the perforated connector suitable for common use injavascript:confirm_mark(`abe`, `1`); civil and bridge engineering are proposed. The connectors were tested in laboratories of CTU Prague for shear load capacity.
Josef Machacek, Jiri Studnicka
openaire   +1 more source

New Shear Connectors Based on PBL Shear Connector For Composite Arch Members

Structural Engineering International, 2014
Perfobond Hoop (PBH) is a newly proposed shear connector based on the perfobond Leisten (PBL) connectors aiming at steel box–concrete composite sections for composite arch members, which has been p...
Liang Fan, Zhixiang Zhou
openaire   +1 more source

Shear Capacity Assessment of Steel-To-CLT Connectors

2023
In modern prefabricated wooden buildings, CLT elements (Cross Laminated Timber, also known as Xlam, CrossLam or BSP) are assembled into macro elements (e.g., walls and slabs) and anchored by means of steel brackets and fasteners. A wide variety of such elements, in the shape of nails, screws and bolts, has been used in the construction market in recent
Matteo Salvalaggio   +2 more
openaire   +2 more sources

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