Results 81 to 90 of about 4,685,864 (234)

Lack of specific binding of Shiga-like toxin (verocytotoxin) and non-specific interaction of Shiga-like toxin 2 antibody with human polymorphonuclear leucocytes [PDF]

Nephrology Dialysis Transplantation, 2007
After gastrointestinal infection with Shiga-like toxin (Stx) producing Escherichia coli, the toxin is transported from the intestine to the renal microvascular endothelium. This is the main target for Stx in humans. Previous studies indicated that polymorphonuclear leucocytes (PMN) could serve as carriers for Stx in the systemic circulation.
Geelen, J.M., Velden, T.J.A.M. van der, Loo, D.M.W.M. te, Boerman, O.C., Heuvel, L.P.W.J. van den, Monnens, L.A.H.   +5 more
openaire   +3 more sources

Identifikasi Escherichia coli O157:H7 serta Deteksi Gen Shiga Like Toxin 1 dan 2 Asal Feses Hewan, Daging, dan Feses Manusia

Jurnal Veteriner, 2016
Escherichia coli O157:H7 with the ability to produce shiga-like toxin was isolated from beef, cattle,chicken, and human feces. Due to its importance to human health, it is necessary to identify the genesencoding the production of shiga-like toxin, stx1 ...
I Wayan Suardana, Wayan Tunas Artama, Widya Asmara, Budi Setiadi Daryono   +3 more
doaj  

Typical and Atypical Enteropathogenic Escherichia coli

Emerging Infectious Diseases, 2002
Typical and atypical enteropathogenic Escherichia coli (EPEC) strains differ in several characteristics. Typical EPEC, a leading cause of infantile diarrhea in developing countries, is rare in industrialized countries, where atypical EPEC seems to be a ...
Luiz R. Trabulsi, Rogéria Keller, Tânia A. Tardelli Gomes   +2 more
doaj   +1 more source

Schisandrin C Targets PPARγ to Induce Ferroptosis in Colorectal Cancer Cells and Promote M1 Macrophage Polarization

Phytotherapy Research, EarlyView.
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei, Hong‐Ping Wen, Jian‐Bo Song, Jin‐Fang Xu, Hong‐Rui Guo   +4 more
wiley   +1 more source

A mutant Shiga-like toxin IIe bound to its receptor Gb 3 : structure of a group II Shiga-like toxin with altered binding specificity [PDF]

Structure, 2000
Shiga-like toxins (SLTs) are produced by the pathogenic strains of Escherichia coli that cause hemorrhagic colitis and hemolytic uremic syndrome. These diseases in humans are generally associated with group II family members (SLT-II and SLT-IIc), whereas SLT-IIe (pig edema toxin) is central to edema disease of swine.
Ling, Hong, Pannu, Navraj S, Boodhoo, Amechand, Armstrong, Glen D, Clark, Clifford G, Brunton, James L, Read, Randy J   +6 more
openaire   +2 more sources

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +2 more sources

Regulatory elements of stx2 gene and the expression level of Shiga-like toxin 2 in Escherichia coli O157:H7

Journal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Shiga-like toxin (Stx) is an important factor in the pathogenesis of Escherichia coli O157:H7 infection and is responsible for some severe complications. Stx2 is usually associated with hemolytic uremic syndrome in humans.
I Wayan Suardana, Komang Januartha Putra Pinatih, Dyah Ayu Widiasih, Wayan Tunas Artama, Widya Asmara, Budi Setiadi Daryono   +5 more
doaj   +1 more source

Synthesis of Chiral Gold Nanostructures on Gold‐Coral‐Coated Transparent Conductive Oxide Substrates via [AuCl4]– and Cysteine Interactions for Enhanced Chiral Sensing

Small, EarlyView.
We developed hierarchical chiral Au nanostructures on Au coral structures on transparent conductive oxide substrates using only electrochemical methods. By controlling the interaction between [AuCl4]– and cysteine, we successfully tuned the morphology and circular dichroism of the resulting Au nanostructures.
Kenta Nakagawa, Junhe Wang, Tianji Zhang, Yuta Shiga, Olga Guselnikova, Takuya Nakanishi, Yusuke Yamauchi, Toru Asahi   +7 more
wiley   +1 more source

Comparative analysis of two complete Corynebacterium ulcerans genomes and detection of candidate virulence factors [PDF]

, 2011
Trost E, Al-Dilaimi A, Papavasiliou P, et al. Comparative analysis of two complete Corynebacterium ulcerans genomes and detection of candidate virulence factors. BMC Genomics.
Viehöver, Prisca, Sabbadini, Priscila, Trost, Eva ; https://orcid.org/, Santos, Louisy S., Burkovski Andreas, Cíntia S Santos, Viehoever Prisca, Burkovski, Andreas, Soares Siomar C, Dias, Alexandre A., Schneider, Jessica, Ana L Mattos-Guaraldi, Schneider Jessica, Silva, Artur, Almeida, Sintia S., Jessica Schneider, Papavasiliou, Panagiotis, Dorella, Fernanda A., Tauch Andreas, Andreas Burkovski, Santos Cíntia S, Azevedo, Vasco, Eva Trost, Louisy S Santos, Hirata, Raphael Jr, Silva Artur, Sabbadini Priscila, Azevedo Vasco, Tauch, Andreas, Prisca Viehoever, Santos, Cintia S., Schneider Maria P, Miyoshi Anderson, Soares, Siomar C., Siomar C Soares, Vasco Azevedo, Mattos-Guaraldi, Ana L., Fernanda A Dorella, Schneider, Maria P., Maria P Schneider, Miyoshi, Anderson, Al-Dilaimi Arwa, Dorella Fernanda A, Raphael Hirata, Alexandre A Dias, Arwa Al-Dilaimi, Anderson Miyoshi, Al-Dilaimi, Arwa, Hirata Raphael, Almeida Sintia S, Mattos-Guaraldi Ana L, Andreas Tauch, Panagiotis Papavasiliou, Santos Louisy S, Sintia S Almeida, Priscila Sabbadini, Papavasiliou Panagiotis, Artur Silva, Dias Alexandre A, Trost Eva   +59 more
core   +2 more sources

Exploiting Phase Partitioning of a Giant Trimeric Fibrous Protein Scaffold to Potentiate Chitinase‐Driven Antifungal Activity

Small, EarlyView.
Cstalk, a giant fibrous protein, selectively partitions into the dextran‐rich phase in polyethylene glycol/dextran aqueous two‐phase systems, functioning as a recruiter for proteins of interest. This phase‐selective recruitment can be extended to fungal cell walls, enabling the targeted localization of enzymes and enhancing antifungal activity through ...
Ayasa Nagatani, Shogo Yoshimoto, Toki Taira, Rie Wakabayashi, Masahiro Goto, Katsutoshi Hori, Noriho Kamiya   +6 more
wiley   +1 more source