Results 71 to 80 of about 14,812 (194)
The FEBS Journal, EarlyView.We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
Shiga Toxins and the Pathophysiology of Hemolytic Uremic Syndrome in Humans and Animals
Toxins, 2012 Food-borne diseases are estimated at 76 million illnesses and 5000 deaths every year in the United States with the greatest burden on young children, the elderly and immunocompromised populations.
Deborah J. Stearns-Kurosawa +3 more
doaj +1 more source
Ligand binding represses bacterial histidine kinase activity by inhibiting its dimerization
The FEBS Journal, EarlyView.PdtaS is a kinase in the pathogen Mycobacterium tuberculosis that senses copper and nitric oxide and controls virulence gene expression, but how the kinase senses these compounds was unclear. We show that PdtaS is active as a dimer with each monomer phosphorylating the other in trans.
Gaurav D. Sankhe +6 more
wiley +1 more source
Indian Journal of Pathology and Microbiology, 2010 Purpose: This study was conducted to study the prevalence of diarrheagenic Escherichia coli (DEC) in dysentery cases with special reference to Shiga-like toxin producing Escherichia coli (STEC).
Lanjewar Mrudul, De Anuradha, Mathur M
doaj
Preventing Foodborne Illness: Shigellosis
EDIS, 2005 Shigella is a Gram-negative, nonmotile, non-sporeforming, rod-shaped bacterium capable of causing disease in humans. Disease occurs when virulent Shigella organisms are consumed and invade the intestinal mucosa, resulting in tissue destruction.
Keith R. Schneider +3 more
doaj +1 more source
International Endodontic Journal, EarlyView.ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa +5 more
wiley +1 more source
Beraprost Attenuates Starvation‐Induced Apoptosis and Protects Feline Endothelial Cells
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.This study established a feline endothelial cell starvation model to test the anti‐apoptotic effects of beraprost and its stereoisomers. Beraprost and beraprost‐314d reduced starvation‐induced apoptosis by inhibiting caspase‐3/7 activity and modulating Bax expression, while beraprost‐315d was less potent.
Takumi Matsuura +2 more
wiley +1 more source
Jurnal Veteriner, 2010 Escherichia coli O157:H7 with the ability to produce shiga-like toxin was isolated from beef, cattle, chicken, and human feces. Due to its importance to human health, it is necessary to identify the genes encoding the production of shiga-like toxin, stx1
I Wayan Suardana +3 more
doaj
Assessment of Cell Cycle and Induction of Apoptosis by Shiga-like Toxin Produced by Escherichia coli O157:H7 in T47D Breast Cancer Cells Using Flow Cytometry. [PDF]
Asian Pac J Cancer Prev, 2022 Suardana IW +4 more
europepmc +1 more source
Identification of Potential Vaccine Strains of Escherichia coli Isolates From Diarrhoeic Calves
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.This study aimed to identify vaccine candidate Escherichia coli strains isolated from diarrheic calves. Faecal samples collected from 500 calves were analysed, and E. coli strains were isolated and characterized phenotypically and genotypically. Antibiotic resistance profiles, virulence‐associated genes and MLVA genotyping were used to select 20 ...
Yasemin Erdoğan +16 more
wiley +1 more source