Results 61 to 70 of about 4,685,864 (234)

Comparative Pathogenicity of Wildlife and Bovine Escherichia coli O157:H7 Strains in Experimentally Inoculated Neonatal Jersey Calves

Veterinary Sciences, 2018
Shiga toxin-producing Escherichia coli, like E. coli O157:H7, are important human and animal pathogens. Naturally-acquired E. coli O157:H7 infections occur in numerous species but, particularly, cattle have been identified as a significant reservoir for ...
Elizabeth M. Antaki-Zukoski, Xunde Li, Patricia A. Pesavento, Tran H. B. Nguyen, Bruce R. Hoar, Edward R. Atwill   +5 more
doaj   +1 more source

ArcA positively regulates the expression of virulence genes and contributes to virulence of porcine Shiga toxin-producing enterotoxigenic Escherichia coli

Microbiology Spectrum, 2023
Enterotoxigenic Escherichia coli (ETEC) cause severe diarrhea in humans and animals. These bacteria encode two major classes of virulence factors, adhesins that promote colonization of the small intestine and enterotoxins that induce fluid secretion and ...
Fengwei Jiang, Yan Yang, Zhao Mao, Wentong Cai, Ganwu Li   +4 more
doaj   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Expression and purification of Shiga-like toxin II B subunits [PDF]

Infection and Immunity, 1995
Shiga-like toxins (SLTs), which are produced by certain strains of Escherichia coli, are composed of enzymatically active A and B subunit multimers responsible for the toxin's binding. We have previously purified large amounts of the SLT-I B subunit by using a hyperexpression vector in Vibrio cholerae under the control of the trc promoter.
D W, Acheson, S A, De Breucker, M, Jacewicz, L L, Lincicome, A, Donohue-Rolfe, A V, Kane, G T, Keusch   +6 more
openaire   +2 more sources

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Design of targeted B cell killing agents. [PDF]

PLoS ONE, 2011
B cells play an important role in the pathogenesis of both systemic and organ-specific autoimmune diseases. Autoreactive B cells not only produce autoantibodies, but also are capable to efficiently present specific autoantigens to T cells. Furthermore, B
Alexey V Stepanov, Alexey A Belogurov, Natalia A Ponomarenko, Oleg A Stremovskiy, Leonid V Kozlov, Anna M Bichucher, Sergey E Dmitriev, Ivan V Smirnov, Olga G Shamborant, Dmitry S Balabashin, Lidia P Sashchenko, Alexander G Tonevitsky, Alain Friboulet, Alexander G Gabibov, Sergey M Deyev   +14 more
doaj   +1 more source

Detection of Shiga-like toxin producing Escherichia coli from raw milk cheeses produced in Wallonia [Belgium]. [PDF]

Biotechnologie, Agronomie, Société et Environnement, 1999
Shiga-like toxin Escherichia coli (STEC) implicated in aqueous diarrhoea, haemorrhagic colitis and haemolytic uraemic syndrome, has become a serious health problem in various countries. In Belgium, all cases are sporadic and no outbreak has been detected
El-Lioui M., Vivegnis J., Leclercq A., Lambert B., Decallonne J.   +4 more
doaj  

Charged and hydrophobic surfaces on the a chain of shiga-like toxin 1 recognize the C-terminal domain of ribosomal stalk proteins. [PDF]

PLoS ONE, 2012
Shiga-like toxins are ribosome-inactivating proteins (RIP) produced by pathogenic E. coli strains that are responsible for hemorrhagic colitis and hemolytic uremic syndrome.
Andrew J McCluskey, Eleonora Bolewska-Pedyczak, Nick Jarvik, Gang Chen, Sachdev S Sidhu, Jean Gariépy   +5 more
doaj   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

Aplikasi Kandidat Pemindai untuk Diagnosis Gen Shiga like toxin-2 dari Escherichia coli O157:H7 (PROBE APLICATION TO DIAGNOSTIC PROGRAME OF SHIGA LIKE TOXIN-2 (STX2) GEN FROM ESCHERICHIA COLI O157:H7)

Jurnal Veteriner, 2013
A Shiga-like toxin producing Escherichia coli O157:H7 has been detected in cattle fecal sample, atbeef, and human as well as in beef and indicating that the agent is a harmful zoonosis bacteria. Geneticanalysis of Shiga toxin Escherichia coli (STEC) gene
I Wayan Suardana, I Nengah Sujaya, Wayan Tunas Artama   +2 more
doaj