Results 11 to 20 of about 335,942 (340)
Shiga Toxin Therapeutics: Beyond Neutralization [PDF]
Toxins, 2017 Ribotoxic Shiga toxins are the primary cause of hemolytic uremic syndrome (HUS) in patients infected with Shiga toxin-producing enterohemorrhagic Escherichia coli (STEC), a pathogen class responsible for epidemic outbreaks of gastrointestinal disease ...
G. Hall +2 more
semanticscholar +4 more sources
Chemosensors, 2022 Foodborne bacteria have persisted as a significant threat to public health and to the food and agriculture industry. Due to the widespread impact of these pathogens, there has been a push for the development of strategies that can rapidly detect ...
Sabrina Petrucci +3 more
doaj +1 more source
Bacteriophages of Shiga Toxin-Producing Escherichia coli and Their Contribution to Pathogenicity
Pathogens, 2021 Shiga toxins (Stx) of Shiga toxin-producing Escherichia coli (STEC) are generally encoded in the genome of lambdoid bacteriophages, which spend the most time of their life cycle integrated as prophages in specific sites of the bacterial chromosome.
Lorena Rodríguez-Rubio +4 more
semanticscholar +1 more source
Influence of temperature and pH on induction of Shiga toxin Stx1a in Escherichia coli
Frontiers in Microbiology, 2023 Shiga toxin-producing strains represent pathogenic group that is of concern in food production. The present study evaluated forty-eight E. coli isolates (11 with intact stx gene, while remaining isolates presented only stx-fragments) for Shiga toxin ...
Vinicius Silva Castro +2 more
doaj +1 more source
Characterization of Atypical Shiga Toxin Gene Sequences and Description of Stx2j, a New Subtype
Journal of Clinical Microbiology, 2022 Shiga toxin (Stx) is the definitive virulence factor of Shiga toxin-producing Escherichia coli (STEC). Stx variants are currently organized into a taxonomic system of three Stx1 (a, c, and d) and seven Stx2 (a, b, c, d, e, f, and g) subtypes.
A. Gill +9 more
semanticscholar +1 more source
Shiga and Shiga-like toxins [PDF]
Microbiological Reviews, 1987 Introduction . 206 Shiga Toxin in Shigella Spp. . 207 History . 207 Purification and Structure . 207 Mode of Action . 208 Receptor binding and internalization . 208 Inhibition of protein synthesis . 209 Immunology and Immunochemistry . 209 Genetics . 210 Role of Toxin in Disease . 210 Dysentery . 210 Diarrhea .210 HUS . 211 Shiga-like toxins in E. Coli
O'Brien, Alison D., Holmes, Randall K.
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Shiga Toxins as Antitumor Tools [PDF]
Toxins, 2021 Shiga toxins (Stxs), also known as Shiga-like toxins (SLT) or verotoxins (VT), constitute a family of structurally and functionally related cytotoxic proteins produced by the enteric pathogens Shigella dysenteriae type 1 and Stx-producing Escherichia coli (STEC). Infection with these bacteria causes bloody diarrhea and other pathological manifestations
Robert, Aude, Wiels, Joëlle
openaire +3 more sources
Shiga Toxin-Associated Hemolytic Uremic Syndrome: A Narrative Review
Toxins, 2020 The severity of human infection by one of the many Shiga toxin-producing Escherichia coli (STEC) is determined by a number of factors: the bacterial genome, the capacity of human societies to prevent foodborne epidemics, the medical condition of infected
Adrien Joseph +4 more
semanticscholar +1 more source
Shiga Toxin-Producing Escherichia coli: Detection, Differentiation, and Implications for Food Safety
EDIS, 2016 Shiga toxin is a protein found within the genome of a type of virus called a bacteriophage. These bacteriophages can integrate into the genomes of the bacterium E. Coli. Even though most E. coli are benign or even beneficial members of our gut microbial
William J. Zaragoza +2 more
doaj +5 more sources