Results 81 to 90 of about 366,512 (248)

Locus of Adhesion and Autoaggregation (LAA), a pathogenicity island present in emerging Shiga Toxin–producing Escherichia coli strains

Scientific Reports, 2017
Shiga Toxin-producing Escherichia coli (STEC) are a group of foodborne pathogens associated with diarrhea, dysentery, hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS).
D. Montero, Juliana Velasco, Felipe Del Canto, J. Puente, N. Padola, D. Rasko, M. Farfán, J. Salazar, R. Vidal   +8 more
semanticscholar   +1 more source

Flagellin induces β-defensin 2 in human colonic ex vivo infection with enterohemorrhagic Escherichia coli [PDF]

, 2016
Enterohemorrhagic E. coli (EHEC) is an important foodborne pathogen in the developed world and can cause life-threatening disease particularly in children.
Chan, Simon, Cook, Vivienne, Ellis, Samuel, Gelson, William, Lewis, Steven, Prior, Alison, Schuller, Stephanie   +6 more
core   +1 more source

Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy

Toxins, 2020
Shiga toxin (STx) produced by Shigella and closely related Shiga toxin 1 and 2 (STx1 and STx2) synthesized by Shiga toxin-producing Escherichia coli (STEC) are bacterial AB5 toxins.
Danyang Li, Andrey Selyunin, Somshuvra Mukhopadhyay   +2 more
doaj   +1 more source

Transforming Shiga toxin-producing Escherichia coli surveillance through whole genome sequencing in food safety practices

Frontiers in Microbiology, 2023
IntroductionShiga toxin-producing Escherichia coli (STEC) is a gastrointestinal pathogen causing foodborne outbreaks. Whole Genome Sequencing (WGS) in STEC surveillance holds promise in outbreak prevention and confinement, in broadening STEC epidemiology
Stéphanie Nouws, Stéphanie Nouws, Bavo Verhaegen, Sarah Denayer, Florence Crombé, Denis Piérard, Bert Bogaerts, Kevin Vanneste, Kathleen Marchal, Kathleen Marchal, Nancy H. C. Roosens, Sigrid C. J. De Keersmaecker   +11 more
doaj   +1 more source

A preliminary study of the use of MinION sequencing to specifically detect Shiga toxin-producing Escherichia coli in culture swipes containing multiple serovars of this species

Scientific Reports, 2023
An important challenge relating to clinical diagnostics of the foodborne pathogen Shiga toxin-producing E. coli (STEC), is that PCR-detection of the shiga-toxin gene (stx) in DNA from stool samples can be accompanied by a failure to identify an STEC ...
Hege S. Tunsjø, Ingvild Falkum Ullmann, Colin Charnock   +2 more
doaj   +1 more source

Isolation of Shiga toxin-producing Escherichia coli harboring variant Shiga toxin genes from seafood [PDF]

Veterinary World, 2018
Background and Aim: Shiga toxin-producing Escherichia coli (STEC) are important pathogens of global significance. STEC are responsible for numerous food-borne outbreaks worldwide and their presence in food is a potential health hazard.
Sreepriya Prakasan, Parmanand Prabhakar, Manjusha Lekshmi, Binaya Bhusan Nayak, Sanath Kumar   +4 more
doaj   +1 more source

C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

iScience, 2022
Summary: The development of anti-infectives against a large range of AB-like toxin-producing bacteria includes the identification of compounds disrupting toxin transport through both the endolysosomal and retrograde pathways.
Yu Wu, Nassim Mahtal, Eléa Paillares, Léa Swistak, Sara Sagadiev, Mridu Acharya, Caroline Demeret, Sylvie Van Der Werf, Florence Guivel-Benhassine, Olivier Schwartz, Serena Petracchini, Amel Mettouchi, Lucie Caramelle, Pierre Couvineau, Robert Thai, Peggy Barbe, Mathilde Keck, Priscille Brodin, Arnaud Machelart, Valentin Sencio, François Trottein, Martin Sachse, Gaëtan Chicanne, Bernard Payrastre, Florian Ville, Victor Kreis, Michel-Robert Popoff, Ludger Johannes, Jean-Christophe Cintrat, Julien Barbier, Daniel Gillet, Emmanuel Lemichez   +31 more
doaj   +1 more source

Applying phylogenomics to understand the emergence of Shiga Toxin producing Escherichia coli O157:H7 strains causing severe human disease in the United Kingdom [PDF]

, 2015
Shiga Toxin producing Escherichia coli (STEC) O157:H7 is a recently emerged zoonotic pathogen with considerable morbidity. Since the serotype emerged in the 1980s, research has focussed on unravelling the evolutionary events from the E.
Allison, Lesley, Ashton, Philip M., Byrne, Lisa, Chase-Topping, Margo E., Dallman, Timothy J., Ellis, Richard, Gally, David L., Grant, Kathie A., Gunn, George G., Hanson, Mary, Holmes, Anne, Jenkins, Claire, Perry, Neil T., Petrovska, Liljana, Wain, John, Woolhouse, Mark E.J.   +15 more
core   +2 more sources

Sub-Lethal Dose of Shiga toxin 2 from Enterohemorrhagic Escherichia coli Affects Balance and Cerebellar Cythoarquitecture.

Frontiers in Microbiology, 2016
Shiga toxin producing Escherichia coli may damage the central nervous system before or concomitantly to manifested hemolytic uremic syndrome symptoms.
Luciana eD’Alessio, Alipio ePinto, Adriana eCangelosi, Patricia eGeoghegan, Carla eTironi-Farinati, Gabriela eBrener, Jorge eGoldstein   +6 more
doaj   +1 more source

Non-O157 Shiga Toxin–producing Escherichia coli Associated with Venison

Emerging Infectious Diseases, 2012
We investigated an outbreak of non-O157 Shiga toxin–producing Escherichia coli at a high school in Minnesota, USA, in November 2010. Consuming undercooked venison and not washing hands after handling raw venison were associated with illness. E. coli O103:
Joshua M. Rounds, Carrie E. Rigdon, Levi J. Muhl, Matthew Forstner, Gregory T. Danzeisen, Bonnie S. Koziol, Charlott Taylor, Bryanne T. Shaw, Ginette L. Short, Kirk Smith   +9 more
doaj   +1 more source