Results 131 to 140 of about 22,481 (247)

Cytochrome P450 1a (CYP1A)‐Knockout Javanese Medaka Fish Exhibit Diabetic Traits and Reduced Reproductive Capacity

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Analyses of cytochrome P450 1a (CYP1A)‐knockout (KO) Javanese medaka (Oryzias javanicus) revealed that CYP1A is involved in glucose regulation and reproduction. In the KO fish, significant increases in hepatic transcripts of insulin, glucagon, and somatostatin genes, as well as elevated blood glucose, liver mass, and liver triglyceride levels ...
Suhaila Rusni   +10 more
wiley   +1 more source

Draft Genome Sequence of an Escherichia coli O157:H43 Strain Isolated from Cattle

open access: yes, 2013
Here we report the draft genome sequence of an Escherichia coli O157:H43 strain, designated T22, with an atypical virulence gene profile and isolated from healthy cattle.
Maróti, Gergely   +4 more
core   +1 more source

Advances in High‐Throughput Sequencing: Antimicrobial Resistance and Traceability of Foodborne Pathogens

open access: yeseFood, Volume 7, Issue 3, June 2026.
In this graphical abstract, the transfer experiment of antimicrobial resistance genes and metagenomic analysis are presented, and they are the core components of relevant microbial research. ABSTRACT High‐throughput sequencing technology (HTST) can effectively analyze the sequence information in the DNA of samples and provide a comprehensive ...
Kexuan Wu   +8 more
wiley   +1 more source

Deteksi Produksi Toksin Stx-1 dan Stx-2 dari Escherichia coli O157:H7 Isolat Lokal Hasil Isolasi Feses dan Daging Sapi

open access: yesJurnal Veteriner, 2009
Shiga toxin produced by Escherichia coli O157:H7 can cause outbreaks and sporadic cases of serioushuman diseases. The diseases are indicated by hemorrhagic colitis and hemolytic uremic syndrome.
I Wayan Suardana   +3 more
doaj  

Efficacy and safety of eculizumab in children with Shiga-toxin-producing Escherichia coli haemolytic uraemic syndrome: the ECUSTEC RCT

open access: yesEfficacy and Mechanism Evaluation
Background Shiga-toxin-producing Escherichia coli haemolytic uraemic syndrome affects ~100 United Kingdom children each year. Around half need dialysis, a quarter develop serious complications with long-term consequences and ~3% die.
Natalie Ives   +11 more
doaj   +1 more source

Edible Fungus Compound Cordycepin Protects Against Acetaminophen‐Induced Liver Injury

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
This study demonstrates that pretreatment with cordycepin (COR) effectively protects against acetaminophen (APAP)‐induced acute liver injury in mice. COR mitigates liver damage by exerting strong antioxidant, anti‐inflammatory, and anti‐apoptotic effects through the modulation of ER proteostasis, HIF‐1, and PPAR signaling networks.
Chunjin Fu   +5 more
wiley   +1 more source

Sexually Dimorphic Regulation of MiR‐29a/c‐3p in Human Endothelial Cells: Cell Functions and Transcriptome

open access: yesJournal of Cellular Physiology, Volume 241, Issue 6, June 2026.
ABSTRACT Preeclampsia (PE) is a major cause of maternal and fetal morbidity and mortality during pregnancy. PE is characterized by widespread endothelial dysfunction in mothers and fetuses. The etiology of PE remains elusive, but the dysregulation of microRNAs (miRNAs) in endothelial cells may contribute to the pathogenesis of PE. We have reported that
Si‐yan Zhang   +3 more
wiley   +1 more source

Exploiting the retrograde transport of disarmed toxins for the delivery of exogenous antigens into MHC class 1 presentation pathway [PDF]

open access: yes
The targeting of exogenous antigen into the MHC class 1-restricted presentation pathway is required for the induction of cytotoxic T lymphocytes (CTL) which have been shown to be an important component of the protective response to intracellular ...
Noakes, Karen
core  

Emerging Dissemination of blaCTX‐M‐65 in Bovine E. coli in Spain Associated With IncHI2 Plasmids

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The resistome in ESBL/AmpC‐producing E. coli in livestock was diverse and dominated by plasmid‐borne genes Detection of host‐independent dissemination of AMR determinants mediated by shared plasmid types First report in Spanish cattle of blaCTX‐M‐65 on IncHI2 plasmids, an under‐reported ESBL in Europe Identification of potentially zoonotic clones in ...
Medelin Ocejo   +2 more
wiley   +1 more source

GA enhances Shiga toxin localization to the Golgi.

open access: yes, 2015
(A) HEp-2 cells were treated with 10 μM GA for 30 min before ~100 ng/ml Shiga toxin 1 mutant was added and the incubation continued for 30 min. Subsequently, cells were fixed, permeabilized and stained with antibodies against Shiga toxin (magenta) and ...
Ieva Ailte Hjelseth (745961)   +4 more
core   +1 more source

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