Results 1 to 10 of about 350,633 (266)

Impact of Skin Disinfection on Cutaneous Microbiota, before and after Peripheral Venous Catheter Insertion

Antibiotics, 2022
Introduction. Patients with invasive medical devices are at high risk for infection. Skin colonization is the initial stage of these infections, leading to the recommendation of practices requiring disinfection using antiseptics.
Manon Prat, Jeremy Guenezan, Bertrand Drugeon, Christophe Burucoa, Olivier Mimoz, Maxime Pichon   +5 more
doaj   +1 more source

Emergence of optrA-mediated linezolid resistance in clinical isolates of Enterococcus faecalis from Argentina

Journal of Global Antimicrobial Resistance, 2023
: Objectives: The aim of this study was to characterize the first 14 optrA-carrying linezolid resistant E. faecalis clinical isolates recovered in seven Argentinian hospitals between 2016 and 2021.
Paula Gagetti, Diego Faccone, Paola Ceriana, Celeste Lucero, Alejandra Menocal, Grupo LRE Argentina, Alejandra Corso   +6 more
doaj   +1 more source

Co-integrate Col3m bla NDM-1-harboring plasmids in clinical Providencia rettgeri isolates from Argentina

Microbiology Spectrum, 2023
The first cases of bla NDM in Argentina were detected in three Providencia rettgeri (Pre) recovered from two hospitals in Buenos Aires city in 2013. The isolates were genetically related, but the plasmid profile was different.
Denise De Belder, Florencia Martino, Nathalie Tijet, Roberto G. Melano, Diego Faccone, Juan Manuel De Mendieta, Melina Rapoport, Ezequiel Albornoz, Alejandro Petroni, Ezequiel Tuduri, Laura Derdoy, Sandra Cogut, Laura Errecalde, Fernando Pasteran, Alejandra Corso, Sonia A. Gomez   +15 more
doaj   +1 more source

Effect of Different Tolerable Levels of Constitutive mcr-1 Expression on Escherichia coli

Microbiology Spectrum, 2022
To study the effect of different tolerable levels of constitutive mcr-1 expression on Escherichia coli, and to provide direct evidence for moderate resistance mediated by mcr-1, construction of E.
Han Qiao, Jie Yu, Xiukun Wang, Tongying Nie, Xinxin Hu, Xinyi Yang, Congran Li, Xuefu You   +7 more
doaj   +1 more source

Evolution and development of potent monobactam sulfonate candidate IMBZ18g as a dual inhibitor against MDR Gram-negative bacteria producing ESBLs

Acta Pharmaceutica Sinica B, 2023
A series of new monobactam sulfonates is continuously synthesized and evaluated for their antimicrobial efficacies against Gram-negative bacteria. Compound 33a (IMBZ18G) is highly effective in vitro and in vivo against clinically intractable multi-drug ...
Zhiwen Li, Zhihao Guo, Xi Lu, Xican Ma, Xiukun Wang, Rui Zhang, Xinxin Hu, Yanxiang Wang, Jing Pang, Tianyun Fan, Yonghua Liu, Sheng Tang, Haigen Fu, Jingpu Zhang, Yinghong Li, Xuefu You, Danqing Song   +16 more
doaj   +1 more source

Fluoroquinolone Antimicrobial Agents [PDF]

New England Journal of Medicine, 1989
The fluoroquinolones, a new class of potent orally absorbed antimicrobial agents, are reviewed, considering structure, mechanisms of action and resistance, spectrum, variables affecting activity in vitro, pharmacokinetic properties, clinical efficacy, emergence of resistance, and tolerability. The primary bacterial target is the enzyme deoxyribonucleic
D C, Hooper, J S, Wolfson
openaire   +3 more sources

Evaluation of Agar Dilution Method in Susceptibility Testing of Polymyxins for Enterobacteriaceae and Non-Fermentative Rods: Advantages Compared to Broth Microdilution and Broth Macrodilution

Antibiotics, 2022
An accurate and reliable susceptibility testing method for polymyxins is urgently needed not only for the clinical laboratory but also for new polymyxin-like lipopeptide development.
Xinxin Hu, Lilan Sun, Tongying Nie, Yan Yang, Xiukun Wang, Jing Pang, Xi Lu, Xue Li, Yun Lu, Congran Li, Xinyi Yang, Yao Meng, Guoqing Li, Xuefu You   +13 more
doaj   +1 more source

The combined antibacterial effects of sodium new houttuyfonate and berberine chloride against growing and persistent methicillin-resistant and vancomycin-intermediate Staphylococcus aureus

BMC Microbiology, 2020
Background Infections caused by drug-resistant Staphylococcus aureus, especially vancomycin-intermediate Staphylococcus aureus (VISA), leave clinicians with limited therapeutic options for treatment.
Xue Li, Penghe Wang, Xinxin Hu, Youwen Zhang, Xi Lu, Congran Li, Tongying Nie, Guoqing Li, Xiukun Wang, Jing Pang, Yun Lu, Xinyi Yang, Xuefu You   +12 more
doaj   +1 more source

Antibacterial Activity of an FtsZ Inhibitor Celastrol and Its Synergistic Effect with Vancomycin against Enterococci In Vitro and In Vivo

Microbiology Spectrum, 2023
Enterococci can cause various infectious diseases, including urinary tract infection, wound infection, and life-threatening endocarditis and meningitis.
Xi Lu, Yanxiang Wang, Wei Guo, Zhimeng Zhang, Xinxin Hu, Tongying Nie, Xinyi Yang, Congran Li, Xiukun Wang, Xue Li, Yun Lu, Guoqing Li, Youwen Zhang, Lang Sun, Jing Pang, Xuefu You   +15 more
doaj   +1 more source

Plasmidic resistance to colistin mediated by mcr-1 gene in Escherichia coli clinical isolates in Argentina: A retrospective study, 2012–2018

Revista Panamericana de Salud Pública, 2020
Objective. To describe the resistance profile and the genetic characteristics of Escherichia coli isolates that harbor the mobilizable colistin resistance gene mcr-1 in Argentina. Methods. This was a retrospective study of 192 E.
Diego Faccone, Melina Rapoport, Ezequiel Albornoz, Federico Celaya, Juan De Mendieta, Denise De Belder, Celeste Lucero, Sonia Gomez, Diego Danze, Fernando Pasteran, Alejandra Corso, Mobilizable Colistin Resistance Group   +11 more
doaj   +1 more source