Results 11 to 20 of about 350,633 (266)

Endophytic bacteria from Euphorbia antiquorum L. protect Solanum lycopersicum L. against bacterial wilt caused by Ralstonia solanacearum

open access: yesEgyptian Journal of Biological Pest Control, 2022
Background Bacterial wilt caused by Ralstonia solanacearum (syn. Pseudomonas solanacearum) is the most devastating bacterial disease of tomato (Solanum lycopersicum L.) occurring in tropical zones with consequential substantial yield losses in production
Diane Yimta Youmbi   +6 more
doaj   +1 more source

Microbioassay of Antimicrobial Agents [PDF]

open access: yesApplied Microbiology, 1970
A previously described agar-diffusion technique for microbioassay of antimicrobial agents has been modified to increase sensitivity of the technique and to extend the range of antimicrobial agents to which it is applicable. This microtechnique requires only 0.02 ml of an unknown test sample for assay, and is capable of measuring minute concentrations ...
H J, Simon, E J, Yin
openaire   +2 more sources

Pharmacogenomics of Antimicrobial Agents [PDF]

open access: yesPharmacogenomics, 2014
Antimicrobial efficacy and toxicity varies between individuals owing to multiple factors. Genetic variants that affect drug-metabolizing enzymes may influence antimicrobial pharmacokinetics and pharmacodynamics, thereby determining efficacy and/or toxicity.
Aung, A.K.   +3 more
openaire   +2 more sources

A Mitochondrial Perspective on Noncommunicable Diseases

open access: yesBiomedicines, 2023
Mitochondria are the center of energy metabolism in eukaryotic cells and play a central role in the metabolism of living organisms. Mitochondrial diseases characterized by defects in oxidative phosphorylation are the most common congenital diseases ...
Yifan Zheng   +6 more
doaj   +1 more source

Lectins as antimicrobial agents [PDF]

open access: yesJournal of Applied Microbiology, 2018
The resistance of micro-organisms to antimicrobial agents has been a challenge to treat animal and human infections, and for environmental control. Lectins are natural proteins and some are potent antimicrobials through binding to carbohydrates on microbial surfaces.
L.C. Breitenbach Barroso Coelho   +8 more
openaire   +2 more sources

Polymyxin resistance caused by large-scale genomic inversion due to IS26 intramolecular translocation in Klebsiella pneumoniae

open access: yesActa Pharmaceutica Sinica B, 2023
Polymyxin B and polymyxin E (colistin) are presently considered the last line of defense against human infections caused by multidrug-resistant Gram-negative organisms such as carbapenemase-producer Enterobacterales, Acinetobacter baumannii, and ...
Haibin Li   +15 more
doaj   +1 more source

Potent antiplasmodial extracts and fractions from Terminalia mantaly and Terminalia superba

open access: yesMalaria Journal, 2018
Background The emergence and spread of malaria parasites resistant to artemisinin-based combination therapy stresses the need for novel drugs against malaria.
Cedric D. J. Mbouna   +7 more
doaj   +1 more source

Synthesis and Evolution of Berberine Derivatives as a New Class of Antiviral Agents against Enterovirus 71 through the MEK/ERK Pathway and Autophagy

open access: yesMolecules, 2018
Taking berberine (BBR) as the lead, 23 new BBR derivatives were synthesized and examined for their antiviral activities against four different genotype enterovirus 71 (EV71) strains with a cytopathic effect (CPE) assay.
Yan-Xiang Wang   +8 more
doaj   +1 more source

Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori

open access: yesMolecules, 2020
Taking palmatine (PMT) as the lead, 20 new PMT derivatives were synthesized and examined for their antibacterial activities against six tested metronidazole (MTZ)-resistant Helicobacter pylori (H. pylori) strains.
Tianyun Fan   +7 more
doaj   +1 more source

Characterization of a hypervirulent multidrug-resistant ST23 Klebsiella pneumoniae carrying a blaCTX-M-24 IncFII plasmid and a pK2044-like plasmid

open access: yesJournal of Global Antimicrobial Resistance, 2020
Objective: To characterise a multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKp) strain (Kpn1693) isolated from the sputum of a 67-year-old male patient diagnosed as having bronchiectasis with infection in Northern China.
Yan Yang   +9 more
doaj   +1 more source

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