Results 51 to 60 of about 22,481 (247)

Shiga Toxins: Intracellular Trafficking to the ER Leading to Activation of Host Cell Stress Responses

Toxins, 2010
Despite efforts to improve hygenic conditions and regulate food and drinking water safety, the enteric pathogens, Shiga toxin-producing Escherichia coli (STEC) and Shigella dysenteriae serotype 1 remain major public health concerns due to widespread ...
Moo-Seung Lee, Rama P. Cherla, Vernon L. Tesh   +2 more
doaj   +1 more source

Annexin Induces Cellular Uptake of Extracellular Vesicles and Delays Disease in Escherichia coli O157:H7 Infection

Microorganisms, 2021
Enterohemorrhagic Escherichia coli secrete Shiga toxin and lead to hemolytic uremic syndrome. Patients have high levels of circulating prothrombotic extracellular vesicles (EVs) that expose phosphatidylserine and tissue factor and transfer Shiga toxin ...
Ashmita Tontanahal, Ida Arvidsson, Diana Karpman   +2 more
doaj   +1 more source

Characterization of Purified Shiga Toxin from Shigella dysenteriae 1 [PDF]

Microbiology and Immunology, 1986
AbstractShiga toxin was purified from the culture supernatant of Shigella dysenteriae 1 by ammonium sulfate fractionation, DEAE‐cellulose column chromatography and repeated chromatofocusing column chromatography. About 1.6 mg of purified Shiga toxin was obtained from 15 liters of culture with a yield of about 27%. The molecular weight of purified Shiga
T, Yutsudo, T, Honda, T, Miwatani, Y, Takeda   +3 more
openaire   +2 more sources

Pathogenic Potential to Humans of Bovine Escherichia coli O26, Scotland [PDF]

, 2012
Escherichia coli O26 and O157 have similar overall prevalences in cattle in Scotland, but in humans, Shiga toxin–producing E. coli O26 infections are fewer and clinically less severe than E. coli O157 infections.
Low, JC, Mary F. Hanson, Matthews, L., Alfredo Caprioli, Pollock, K.J., J. Chris Low, Chase-Topping, ME, Caprioli, A, Chase-Topping, M.E., Pearce, M.C., Evans, J., Allison, L.J., Matthews, L, Emily Courcier, Pearce, MC; id_orcid, Michael C. Pearce, David L. Gally, Judith Evans, Courcier, E, Caprioli, A., Locking, M.E., Woolhouse, M.E.J., Allison, LJ, Rosser, T., Handel, I., Louise Matthews, Iain J. McKendrick, Helge Karch, Rosser, T, Gally, DL, Margo E. Chase-Topping, Courcier, E., Tracy Rosser, Gally, D.L., McKendrick, IJ, Evans, J, Karch, H., Hanson, MF, Hanson, Mary, Lesley J. Allison, Low, J.C., Pollock, KGJ, Woolhouse, M.E.; id_orcid, Hanson, M.F., Woolhouse, MEJ, Ian Handel, Pollock, K.G., Mary E. Locking, Karch, H, Kevin G.J. Pollock, Locking, ME, Mark E.J. Woolhouse, Handel, I, McKendrick, I.J.   +53 more
core   +1 more source

Cover 1 - Mesenchymal–Epithelial Transition Response to Shiga Toxin

Cellular and Molecular Gastroenterology and Hepatology, 2020
doaj   +2 more sources

Cytotoxic effect of Shiga toxin-1 on human glomerular epithelial cells [PDF]

Kidney International, 2000
Shiga toxin-1 (Stx-1) has been implicated in the pathogenesis of postdiarrheal hemolytic-uremic syndrome (Stx HUS). Endothelial cells had been felt to be the primary renal target of Stx-1; however, recent studies suggest that renal epithelial cells may also be responsive.
A K, Hughes, P K, Stricklett, D, Schmid, D E, Kohan   +3 more
openaire   +2 more sources

Development of MoSe2 Nano-Urchins as a Sensing Platform for a Selective Bio-Capturing of Escherichia coli Shiga Toxin DNA

Biosensors, 2018
The present study was aimed to develop “fluorine doped” tin oxide glass electrode with a MoSe2 nano-urchin based electrochemical biosensor for detection of Escherichia coli Shiga toxin DNA.
Jagriti Narang, Annu Mishra, Roberto Pilloton, Alekhya VV, Shikha Wadhwa, Chandra Shekhar Pundir, Manika Khanuja   +6 more
doaj   +1 more source

Molecular Characterization of Shiga Toxin-Producing Escherichia coli Strains Isolated in Poland [PDF]

Polish Journal of Microbiology, 2016
Shiga toxin-producing Escherichia coli (STEC) strains also called verotoxin-producing E. coli (VTEC) represent one of the most important groups of food-borne pathogens that can cause several human diseases such as hemorrhagic colitis (HC) and hemolytic ...
Aleksandra Januszkiewicz, Waldemar Rastawicki   +1 more
doaj   +1 more source

Isolation and molecular characterization of Shiga-toxin producing Escherichia coli from betel leaf (Piper betel L.)

Veterinary Research Notes, 2021
Objectives: This study was designed to determine the Shiga-toxin producing genes and investigate antibiotic sensitivity patterns of the Escherichia (E.) coli isolated from ready-to-eat betel leaf from different roadside vendors. Materials and Methods: A
Jafrul Hasan Ripon, Md. Ahosanul Haque Shahid, Md. Muket Mahmud, Shanta Das, Md. Bahanur Rahman, KHM Nazmul Hussain Nazir   +5 more
doaj   +1 more source

Shiga Toxin 1 Targets Bovine Leukemia Virus-Expressing Cells [PDF]

Infection and Immunity, 2004
ABSTRACT Direct evidence that Escherichia coli Shiga toxin (Stx) acts against bovine leukemia virus (BLV)-expressing cells was obtained. The active A subunit of Stx type 1 (StxA1) targeted a selected population of permeable cells expressing BLV and inhibited BLV replication in a culture of bovine ...
Witold A, Ferens, Luke J, Grauke, Carolyn J, Hovde   +2 more
openaire   +2 more sources