Results 111 to 120 of about 22,441 (226)

Shiga Toxin Profiles of Poultry-origin Escherichia coli Isolates with Low Levels of Antimicrobial Resistance to the Clinical and Laboratory Standard Institute-recommended Antibiotics for Surveillance in Human Beings

Indian Journal of Public Health
Background: Escherichia coli are the reservoirs of antimicrobial resistance (AMR) genes. Shiga toxin-producing E. coli of animal origin can cause severe life-threatening infections in man.
Maansi Soodan, Kavita Rana, Ashok Kumar Panda, Krishanender Dinesh, Rajesh Kumar, Rajesh Kumar Vaid, Varun Sankhyan, Sidharath Dev Thakur   +7 more
doaj   +1 more source

Toxin Gene Expression by Shiga Toxin-Producing Escherichia coli: the Role of Antibiotics and the Bacterial SOS Response

Emerging Infectious Diseases, 2000
Toxin synthesis by Shiga toxin-producing Escherichia coli (STEC) appears to be coregulated through induction of the integrated bacteriophage that encodes the toxin gene.
Patrick T. Kimmitt, Colin R. Harwood, Michael R. Barer   +2 more
doaj   +1 more source

Zelluläre Funktionsstudien zum Wirkungsmechanismus von Shiga Toxinen bei mikro- und makrovaskulären Endothelzelllinien [PDF]

, 2010
Bauwens A. Zelluläre Funktionsstudien zum Wirkungsmechanismus von Shiga Toxinen bei mikro- und makrovaskulären Endothelzelllinien. Bielefeld (Germany): Bielefeld University; 2010.Enterohämorrhagische Escherichia coli, die humanpathogene Subgruppe der ...
Bauwens, Andreas
core   +1 more source

GA treatment does not alter Shiga toxin recycling. [PDF]

, 2015
HEp-2 cells were preincubated with 10 μM GA for 30 min at 37°C and subsequently incubated with 40 ng/ml biotinylated Shiga toxin 1 mutant for 30 min. Signals from cell surface-associated Shiga toxin were removed and the toxin chased for another 30 min in
Ieva Ailte Hjelseth (745961), Roger Simm (164068), Maria Lyngaas Torgersen (745962), Anne Berit Dyve Lingelem (745960), Kirsten Sandvig (153014)   +4 more
core   +1 more source

A Poly-N-acetylglucosamine-Shiga toxin broad-spectrum conjugate vaccine for Shiga toxin-producing Escherichia coli. [PDF]

, 2020
Many pathogens produce the β-(1-6)-linked poly-N-acetylglucosamine (PNAG) surface polysaccharide that is being developed as a broadly protective antimicrobial vaccine. However, it is unknown whether systemically injected PNAG vaccines or antibodies would
Roux, D, Gening, ML, Nifantiev, NE, Cywes-Bentley, C, Ritchie, JM, Pier, GB, Munera, D, Skurnik, D, Pozzi, C, Tsvetkov, YE, Lu, X, Waldor, MK   +11 more
core   +1 more source

A Three‐Dimensional Culture–Drug Sensitivity Test Predicts MDM2 Inhibitor–Sensitivity in SMARCB1/INI1‐Deficient Tumors

Cancer Science, EarlyView.
This study aimed to determine whether personalized selection of effective drugs for SMARCB1/INI1‐deficient tumors is feasible using in vitro drug sensitivity profiling. Drug sensitivity was assessed using a short‐term collagen gel–embedded three‐dimensional drug sensitivity test (3D‐DST) in tumors derived from SMARCB1/INI1‐deficient tumor cell line ...
Hiroaki Goto, Chiyoko Nishime, Takashi Ohtsu, Mieko Ito, Maiko Sagisaka, Takuya Naruto, Norihiko Kitagawa, Mio Tanaka, Masakatsu Yanagimachi, Yukihiko Hiroshima, Junko Takita, Yasuhide Hayashi, Yohei Miyagi   +12 more
wiley   +1 more source

Shiga toxin type-2 (Stx2) induces glutamate release via phosphoinositide 3-kinase (PI3K) pathway in murine neurons.

Frontiers in Molecular Neuroscience, 2015
Shiga toxin-producing Escherichia coli (STEC) can cause central nervous system (CNS) damage resulting in paralysis, seizures, and coma. The key STEC virulence factors associated with systemic illness resulting in CNS impairment are Shiga toxins (Stx ...
Fumiko eObata, Fumiko eObata, Lauren M Hippler, Progyaparamita eSaha, Dakshina M Jandhyala, Olga eLatinovic, Olga eLatinovic   +6 more
doaj   +1 more source

Influence of the Escherichia coli oxyR gene function on lambda prophage maintenance [PDF]

, 2010
In Escherichia coli hosts, hydrogen peroxide is one of the factors that may cause induction of lambda prophage. Here, we demonstrate that H2O2-mediated lambda prophage induction is signiWcantly enhanced in the oxyR mutant host. The mRNA levels for cI
Łoś, Marcin, Anna Herman-Antosiewicz, Grzegorz Węgrzyn, Wróbel, Borys, Węgrzyn, Alicja, Szambowska, Anna, Łoś, Joanna, Joanna Całkiewicz, Agata Czyż, Borys Wróbel, Herman-Antosiewicz, Anna, Marcin Łoś, Całkiewicz, Joanna, Joanna M. Łoś, Anna Szambowska, Glinkowska, Monika, Czyż, Agata, Węgrzyn, Grzegorz, Alicja Węgrzyn, Monika Glinkowska   +19 more
core   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Immunomodulation by shiga toxin 2 [PDF]

, 2010
The Shiga-like toxins have DNA sequence homology to the toxins accountable for the dysentery brought about by the Shigella species. Escherichia coli which encode and produce shiga-like toxins are referred to as shiga toxin-producing E.
Chu, Audrey
core