Shiga Toxins as Multi-Functional Proteins: Induction of Host Cellular Stress Responses, Role in Pathogenesis and Therapeutic Applications [PDF]
Toxins, 2016 Shiga toxins (Stxs) produced by Shiga toxin-producing bacteria Shigella dysenteriae serotype 1 and select serotypes of Escherichia coli are primary virulence factors in the pathogenesis of hemorrhagic colitis progressing to potentially fatal systemic ...
Moo-Seung Lee +3 more
doaj +4 more sources
Shiga Toxins Induce Apoptosis and ER Stress in Human Retinal Pigment Epithelial Cells [PDF]
Toxins, 2017 Shiga toxins (Stxs) produced by Shiga toxin-producing bacteria Shigella dysenteriae serotype 1 and select serotypes of Escherichia coli are the most potent known virulence factors in the pathogenesis of hemorrhagic colitis progressing to potentially ...
Jun-Young Park +11 more
doaj +4 more sources
Shiga Toxins and the Pathophysiology of Hemolytic Uremic Syndrome in Humans and Animals [PDF]
Toxins, 2012 Food-borne diseases are estimated at 76 million illnesses and 5000 deaths every year in the United States with the greatest burden on young children, the elderly and immunocompromised populations.
Deborah J. Stearns-Kurosawa +3 more
doaj +4 more sources
P1PK blood group antigens in birds: implications for veterinary blood transfusion, human and pet health [PDF]
BMC Veterinary ResearchBackground The P1PK blood group system in humans, composed of three glycosphingolipid antigens, plays a significant role in transfusion medicine. These antigens are synthesized by the enzyme α1,4-galactosyltransferase, encoded by the A4GALT gene, and ...
Anna Bereznicka +9 more
doaj +2 more sources
The Effect of Mitomycin C on Induction of Shiga Toxin Production in Clinical STEC Isolates [PDF]
ToxinsEarly determination of the Shiga toxin type of Shiga toxin-producing Escherichia coli (STEC) is crucial for guiding STEC-infected patients for proper and timely treatment and patient care.
Surangi H. Thilakarathna +2 more
doaj +2 more sources
Detection of Shiga Toxins by Lateral Flow Assay [PDF]
Toxins, 2015 Shiga toxin-producing Escherichia coli (STEC) produce shiga toxins (Stxs) that can cause human disease and death. The contamination of food products with STEC represents a food safety problem that necessitates rapid and effective detection strategies to ...
Kathryn H. Ching +5 more
doaj +2 more sources
The Interactions of Human Neutrophils with Shiga Toxins and Related Plant Toxins: Danger or Safety?
Toxins, 2012 Shiga toxins and ricin are well characterized similar toxins belonging to quite different biological kingdoms. Plant and bacteria have evolved the ability to produce these powerful toxins in parallel, while humans have evolved a defense system that ...
Maurizio Brigotti
doaj +3 more sources
Shiga Toxins: An Update on Host Factors and Biomedical Applications. [PDF]
Toxins (Basel), 2021 Liu Y, Liu Y, Tian S, Thaker H, Dong M.
europepmc +2 more sources
Проблемы особо опасных инфекций, 2021 Objective – obtaining and characterization of hybrid cell lines producing monoclonal antibodies against I and II types of shiga-like toxins.Materials and methods.
G. V. Kuklina +6 more
doaj +1 more source
Chemosensors, 2022 Foodborne bacteria have persisted as a significant threat to public health and to the food and agriculture industry. Due to the widespread impact of these pathogens, there has been a push for the development of strategies that can rapidly detect ...
Sabrina Petrucci +3 more
doaj +1 more source