Pathogenicity and virulence of Shigella sonnei: A highly drug-resistant pathogen of increasing prevalence [PDF]
Virulence, 2023 Shigella spp. are the causative agent of shigellosis (or bacillary dysentery), a diarrhoeal disease characterized for the bacterial invasion of gut epithelial cells.
Xosé M. Matanza, Abigail Clements
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Macrolide-Resistant Shigella sonnei
Emerging Infectious Diseases, 2008 Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2′-phosphotransferase that inactivates macrolides ...
Leyla Boumghar-Bourtchai +7 more
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Comparative Genomic and Phylogenetic Analysis of a Shiga Toxin Producing Shigella sonnei (STSS) Strain [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Shigella strains are important agents of bacillary dysentery, and in recent years Shigella sonnei has emerged as the leading cause of shigellosis in industrialized and rapidly developing countries. More recently, several S.
Domonkos Sváb +4 more
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Extended spectrum β-lactamase and integron genes among Shigella flexneri and Shigella sonnei isolated from children with diarrhea in shiraz, Southwest Iran [PDF]
BMC PediatricsShigellosis, a bacterial infection marked by dysentery, is typically a self-limiting disease and can be effectively managed with oral rehydration. However, antibiotics may help reduce the severity and duration of Shigellosis despite rising antimicrobial ...
Keyvan Farhadi +5 more
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Antimicrobial resistance patterns and prevalence of class 1 and 2 integrons in
Gut Pathogens, 2010 Background Shigella is a frequent cause of bacterial dysentery in the developing world. Treatment with effective antibiotics is recommended for shigellosis, but options become limited due to globally emerging resistance.
Madiyarov Ruslan S +7 more
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Symptomatic Shigella sonnei urinary tract infection [PDF]
Journal of Clinical Microbiology, 1995 The clinical course for a patient with symptomatic urinary tract infection due to Shigella sonnei is described. The role of Shigella spp. as urinary pathogens is reviewed.
Christopher J. Papasian +2 more
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Case of Extensively Drug-Resistant Shigella sonnei Infection, United States [PDF]
Emerging Infectious Diseases, 2023 We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing
Hosoon Choi +6 more
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Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella [PDF]
mSphereShigella is a leading cause of diarrheal morbidity and mortality in young children from low- and middle-income countries. Here, we aimed to verify the ability of the generalized modules for membrane antigens (GMMA)-based Shigella sonnei candidate vaccine
Arlo Z. Randall +21 more
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A Shigella sonnei clone with extensive drug resistance associated with waterborne outbreaks in China [PDF]
Nature Communications, 2022 Shigella sonnei is a major contributor to the global burden of dysenteric diarrhoea in developed countries. In this work, authors report a S. sonnei clone which has caused numerous waterborne shigellosis outbreaks in China from 2015 to 2020.
Shaofu Qiu +21 more
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Cross-comparison study of three ELISA methodologies to measure Shigella Sonnei O-antigen serum IgG [PDF]
mSphereMeasurement of serum immunoglobulin G (IgG) to Shigella lipopolysaccharide (LPS) has been proposed as a correlate of protection against shigellosis, the confirmation of which in the target population of infants in low- and middle-income countries will ...
Paul Stickings +13 more
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