Pathogenicity and virulence of Shigella sonnei: A highly drug-resistant pathogen of increasing prevalence [PDF]
Virulence, 2023 Shigella spp. are the causative agent of shigellosis (or bacillary dysentery), a diarrhoeal disease characterized for the bacterial invasion of gut epithelial cells.
Xosé M. Matanza, Abigail Clements
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Genetic relatedness among isolates of
BMC Infectious Diseases, 2007 Background Shigella spp. are major cause of diarrhoeal disease in both developing and developed countries. Shigella sonnei is the serogroup of Shigella most frequently responsible for sporadic and epidemic enteritis in developed countries.
Sadeghifard Nourkhoda +5 more
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Macrolide-Resistant Shigella sonnei
Emerging Infectious Diseases, 2008 Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2′-phosphotransferase that inactivates macrolides ...
Leyla Boumghar-Bourtchai +7 more
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Extended spectrum β-lactamase and integron genes among Shigella flexneri and Shigella sonnei isolated from children with diarrhea in shiraz, Southwest Iran [PDF]
BMC PediatricsShigellosis, a bacterial infection marked by dysentery, is typically a self-limiting disease and can be effectively managed with oral rehydration. However, antibiotics may help reduce the severity and duration of Shigellosis despite rising antimicrobial ...
Keyvan Farhadi +5 more
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Case of Extensively Drug-Resistant Shigella sonnei Infection, United States [PDF]
Emerging Infectious Diseases, 2023 We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing
Hosoon Choi +6 more
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Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella [PDF]
mSphereShigella is a leading cause of diarrheal morbidity and mortality in young children from low- and middle-income countries. Here, we aimed to verify the ability of the generalized modules for membrane antigens (GMMA)-based Shigella sonnei candidate vaccine
Arlo Z. Randall +21 more
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Cross-comparison study of three ELISA methodologies to measure Shigella Sonnei O-antigen serum IgG [PDF]
mSphereMeasurement of serum immunoglobulin G (IgG) to Shigella lipopolysaccharide (LPS) has been proposed as a correlate of protection against shigellosis, the confirmation of which in the target population of infants in low- and middle-income countries will ...
Paul Stickings +13 more
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IgG Serum Antibodies to Shigella sonnei Lipopolysaccharide Are Inversely Associated with the Incidence of Culture-Proven S. sonnei Shigellosis in Israeli Children and Adolescents [PDF]
VaccinesBackground: Shigella is a leading cause of moderate-to-severe diarrhea globally, with young children most affected. The burden of shigellosis drops increasingly with age, inferring the acquisition of natural immunity.
Valeria Asato +6 more
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The occurrence of extended-spectrum β-lactamase producing Shigella spp. in Tehran, Iran [PDF]
Iranian Journal of Microbiology, 2013 Background and Objectives: The emergence of extended-spectrum β-lactamase (ESBL)-producing Shigella spp. is of increasing clinical concern specially in children worldwide.
Reza Ranjbar +8 more
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Frontiers in Cellular and Infection Microbiology, 2022 Shigella sonnei is the most common Shigella spp. in developed areas and the second most common in undeveloped regions. In this study, a multiple cross displacement amplification (MCDA) assay was used in combination with a lateral flow biosensor (LFB ...
Yonglu Wang +5 more
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