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Shikimic Acid Pathway

2014
Of the identified biosynthetic paths, shikimic acid pathway plays a very important role in providing precursors of a large number of aromatic compounds of diverse skeletal patterns and substitutions. Chorismic acid, an important branching point product in the shikimic acid pathway also serves as an important precursor. Natural products with C 6 –C 1 or
Sunil Kumar Talapatra, Bani Talapatra
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Shikimate-derived metabolites. 14.1 chiral synthesis of 5-enolpyruvyl-shikimate-3-phosphate

Tetrahedron Letters, 1985
Abstract The title compound, a key biosynthetic intermediate in the shikimate metabolic pathway, has been synthesized in good yield from (−)-shikimic acid ( 1 ).
Chia-Yu P. Teng   +2 more
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Shikimic Acid in Grass

Nature, 1955
IN a paper describing, inter alia, the isolation of quinic acid from grass1, it was suggested that one of the acids (termed ‘acid B’) present in the grass extracts might be shikimic acid or a closely allied acid. Acid B appeared to be identical with ‘acid G’ found by Davies and Hughes2 in grass and stated by them to be a monobasic acid of relatively ...
A. RICHARDSON, A. C. HULME
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Carcinogenicity of bracken and shikimic acid

Nature, 1974
SINCE our initial reports of the carcinogenic potential of bracken for rats and mice1,2 part of our work has been directed towards the isolation of the causative factor(s). The assays used have included acute toxicity testing in mice (orally and intraperitoneally (i.p.)) and mutagen trials with Drosophila and mice, as well as long term cancer induction
I A, Evans, M A, Osman
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Shikimic Acid Pathway: Phenols

2023
Plant metabolites having one or more hydroxyl groups attached to an aromatic ring are known as phenols. Phenols are a heterogeneous group of compounds. One of the most important functions of phenols is in plant communication e.g., allelopathy, attracting pollinating and disseminating agents, attracting symbiotic bacteria, and inhibiting pathogens and ...
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Creation of a Shikimate Pathway Variant

Journal of the American Chemical Society, 2004
The competition between the Escherichia coli carbohydrate phosphotransferase system and 3-deoxy-d-arabino-heptulosonate 7-phosphate (DAHP) synthase for phosphoenolpyruvate limits the concentration and yield of natural products microbially synthesized via the shikimate pathway.
Ningqing, Ran, K M, Draths, J W, Frost
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Genetic analysis of Triticeae shikimate dehydrogenase

Biochemical Genetics, 1988
Starch gel electrophoresis and polyacrylamide gel isoelectric focusing (IEF) were used to investigate the genetic control of Triticeae shikimate dehydrogenase-1 (SKDH-1). Studies of wheat-alien species chromosome addition lines established that Skdh-1 of Hordeum vulgare cv.
BENEDETTELLI, STEFANO, G. E. Hart
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Shikimic Acid Pathway Metabolites

1981
Benzenoid compounds in plants are biosynthesised by two main pathways: the shikimic acid pathway and the acetate-malonate pathway (Chapter 4). In higher plants, a large number of aromatic compounds are derived from phenylalanine, tyrosine and tryptophan, end-products of the shikimic acid pathway.
Margaret L. Vickery, Brian Vickery
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Shikimic Acid Pathway

1998
Most aromatic compounds in plants are derived from shikimic acid metabolism; many of these substances are phenols. Compounds derived from this pathway are extensively modified and considered under other classes of plant secondary metabolites. Although many types of secondary compounds are produced from intermediates of the shikimic acid pathway (e.g ...
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The Shikimate Pathway

1979
The shikimate pathway is the major metabolic route leading to the formation of aromatic compounds in living systems. It operates in microorganisms and in higher plants, but not in animals, which is why the latter are dependent on a dietary supply of the aromatic amino acids phenylalanine, tyrosine and tryptophan.
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