Results 61 to 70 of about 11,222 (183)

The Shikimate Pathway as an Entry to Aromatic Secondary Metabolism [PDF]

Plant Physiology, 1995
The shikimate pathway is often referred to as the common aromatic biosynthetic pathway, even though nature does not synthesize all aromatic compounds by this route. This metabolic sequence converts the primary metabolites PEP and erythrose-4-P to chorismate, the last common precursor for the three aromatic amino acids Phe, Tyr, and Trp and for p-amino ...
openaire   +2 more sources

The conserved Lysine69 residue plays a catalytic role in Mycobacterium tuberculosis shikimate dehydrogenase

BMC Research Notes, 2009
Background The shikimate pathway is an attractive target for the development of antitubercular agents because it is essential in Mycobacterium tuberculosis, the causative agent of tuberculosis, but absent in humans. M. tuberculosis aroE-encoded shikimate
Rodrigues Valnês, Breda Ardala, Santos Diógenes, Basso Luiz   +3 more
doaj  

Global genome analysis of the shikimic acid pathway reveals greater gene loss in host-associated than in free-living bacteria

BMC Genomics, 2010
Background A central tenet in biochemistry for over 50 years has held that microorganisms, plants and, more recently, certain apicomplexan parasites synthesize essential aromatic compounds via elaboration of a complete shikimic acid pathway, whereas ...
Amin Bijal, Hammen Lena, Cercelet François, Cullum John, Shick J Malcolm, Dunlap Walter C, Zucko Jurica, Lau Timothy, Williams Jamal, Hranueli Daslav, Long Paul F   +10 more
doaj   +1 more source

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, EarlyView.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

Targeting upstream and downstream arms of the bacterial shikimate metabolic network as an opportunity for antibacterial and antivirulence therapy

Discover Bacteria
The shikimate pathway is an essential metabolic route in bacteria that generates chorismate, a central intermediate linking primary metabolism to the biosynthesis of aromatic amino acids and diverse infection-relevant metabolites.
Reuben S. Maghembe
doaj   +1 more source

Multi‐Subunit Engineering of Photorespiratory Glycine Decarboxylase Refines Photosynthesis, Growth and Metabolic Robustness of Arabidopsis

Plant, Cell &Environment, EarlyView.
ABSTRACT Photorespiration secures oxygenic photosynthesis from metabolic constraints arising from the oxygenation reaction of Rubisco in today's oxygen‐rich atmosphere. Beyond this protective function, it is vital for primary metabolism, cellular redox balance, and stomatal regulation.
Hu Sun, Yannic C. R. Wagner, Wieke‐Marie Rosenfeldt, Rhena Schumann, Stéphanie Arrivault, Guillaume Decros, Rhiannon Page, Elizabete Carmo Silva, Tracy Lawson, Wei Huang, Alisdair R. Fernie, Hermann Bauwe, Martin Hagemann, Stefan Timm   +13 more
wiley   +1 more source

Metabolic engineering of Corynebacterium glutamicum for the production of anthranilate from glucose and xylose

Microbial Biotechnology
Anthranilate and its derivatives are important basic chemicals for the synthesis of polyurethanes as well as various dyes and food additives. Today, anthranilate is mainly chemically produced from petroleum‐derived xylene, but this shikimate pathway ...
Mario Mutz, Vincent Brüning, Christian Brüsseler, Moritz‐Fabian Müller, Stephan Noack, Jan Marienhagen   +5 more
doaj   +1 more source

Glyphosate residues in soil alter herbivore‐induced plant volatiles and affect predatory insect behaviour

Plant Biology, EarlyView.
Herbicide residues in soil disrupt plant–insect signalling, reducing the effectiveness of biological pest control. Abstract Plants under herbivore attack emit distinct blends of herbivore‐induced plant volatiles (HIPVs) which serve as signalling cues for predatory insects.
B. Fuchs, J. D. Blande, V. Weijola
wiley   +1 more source

Genotype‐Dependent Chemical Diversity and Bioactivity in Purple Elephant Grass: A Metabolomics‐Guided Evaluation for Animal Nutrition

Natural Sciences, Volume 6, Issue 4, October 2026.
ABSTRACT Purple elephant grass (Cenchrus purpureus (Schumach.) Morrone) is a valuable forage crop with potential bioactive properties that influence animal health. This study presents a comprehensive metabolomic characterization of two purple elephant grass genotypes (T441 and T515) using high‐resolution mass spectrometry (HRMS), molecular networking ...
Salva Asghar, Erica A. Batista, Eric de Souza Gil, Gracimerio José Guarneire, Ana Mara F. Nunes, Sandra B. R. de Castro, Alessandra P. Carli, Caio César S. Alves, Juarez C. Machado, Abeer M. Alawi Al‐Sakkaf, Teresinha J. A. S. Andrade, Danielle F. Dias, Marisi G. Soares, Nerilson M. Lima   +13 more
wiley   +1 more source

Engineering of Corynebacterium glutamicum for the synthesis of aromatic compounds

Applied Microbiology and Biotechnology
A significant proportion of industrially important small molecules are aromatic, and the majority of these compounds are produced chemically, relying heavily on fossil resources.
Jan Marienhagen
doaj   +1 more source