Results 41 to 50 of about 21,035 (216)

Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans

Life Science Alliance, 2022
Structural characterization of shikimate pathway multi-enzyme Aro1 from opportunistic fungal pathogen Candida albicans provides the first molecular image of all five domains.
Peter J Stogios, Sean D Liston, Cameron Semper, Bradley Quade, Karolina Michalska, Elena Evdokimova, Shane Ram, Zbyszek Otwinowski, Dominika Borek, Leah E Cowen, Alexei Savchenko   +10 more
doaj   +1 more source

Targeting Shikimate Kinase Pathway of Acinetobacter baumannii: A Structure-Based Computational Approach to Identify Antibacterial Compounds

Journal of Tropical Medicine, 2023
Acinetobacter baumannii (A. baumannii) is an opportunistic bacterium that has developed multidrug resistance (MDR) to most of today’s antibiotics, posing a significant risk to human health.
Aparna Shil, Most. Afrin Akter, Arafin Sultana, Sajal Kumar Halder, Mahbubul Kabir Himel   +4 more
doaj   +1 more source

The formation of homogentisate in the biosynthesis of tocopherol and plastoquinone in spinach chloroplasts [PDF]

, 1982
Homogentisate is the precursor in the biosynthesis of -tocopherol and plastoquinone-9 in chloroplasts. It is formed of 4-hydroxyphenylpyruvate of the shikimate pathway by the 4-hydroxyphenylpyruvate dioxygenase.
B. Buchholz, B. Buchholz, B. Lindblad, D.J. Arnon, Erich Fiedler, G.R. Whistance, Gernot Schultz, H. Beevers, H. Bickel, H. Bickel, H. Bickel, H. Bickel, H.Y. Nakatani, J. Soll, Jürgen Soll, K.G. Hutson, N.E. Tolbert, N.E. Tolbert, O.H. Lowry, P.H. McNeil, R. Douce, R. Douce, R. Douce, R. Douce, R. Hass, T.W. Goodwin, W. Löffelhardt, W. Löffelhardt   +27 more
core   +1 more source

Targeted modulation of the shikimate pathway enhances bacterial wilt resistance through NbMEE32 suppression in tobacco

Industrial Crops and Products
The shikimate pathway serves as a central metabolic route for the biosynthesis of aromatic amino acids and diverse secondary metabolites involved in plant growth and defense.
Dong Cheng, Dan Zhou, Jiahui Wu, Bingsen Wang, Yuhan Li, Botao Song, Huilan Chen, Juan Du   +7 more
doaj   +1 more source

Quinate-enhanced glyphosate toxicity is related to the accumulation of quinate derivatives

Plant Stress
Glyphosate is the most widely used herbicide and works by inhibiting the enzyme 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS) of the shikimate pathway, preventing the aromatic amino acid biosynthesis.
Ainhoa Zulet-Gonzalez, Miriam Gil-Monreal, Karin Gorzolka, Mercedes Royuela, Ana Zabalza   +4 more
doaj   +1 more source

Biosynthesis of α-Tocopherol and Plastoquinone-9 in spinach chloroplasts [PDF]

, 1980
Prenylation and methylation reaction in al biosynthesis is localized in the envelope membranes of the chloroplasts, while PQ-9 biosynthesis takes place in the envelope membranes and also in the thylakoid membranes.
Mazliak, P., Schultz, Gernot, Soll, Jürgen   +2 more
core   +1 more source

Unraveling Shikimate Dehydrogenase Inhibition by 6-Nitroquinazoline-2,4-diol and Its Impact on Soybean and Maize Growth

Agronomy
The shikimate pathway is crucial for the biosynthesis of aromatic amino acids in plants and represents a promising target for developing new herbicides.
Aline Marengoni Almeida, Josielle Abrahão, Flavio Augusto Vicente Seixas, Paulo Sergio Alves Bueno, Marco Aurélio Schüler de Oliveira, Larissa Fonseca Tomazini, Rodrigo Polimeni Constantin, Wanderley Dantas dos Santos, Rogério Marchiosi, Osvaldo Ferrarese-Filho   +9 more
doaj   +1 more source

Biosynthesis of Rifamycins (Ansamycins) and Microbial Production of Shikimate Pathway Precursors, Intermediates, and Metabolites

CHIMIA, 1985
Is the elucidation of biosynthetic pathways of academic interest only, or are there enough valuable spin-offs to make biogenetic studies attractive for a research laboratory in a pharmaceutical company?
Oreste Ghisalba
doaj   +1 more source

Bacteria isolated from Bengal cat (Felis catus × Prionailurus bengalensis) anal sac secretions produce volatile compounds potentially associated with animal signaling. [PDF]

, 2019
In social animals, scent secretions and marking behaviors play critical roles in communication, including intraspecific signals, such as identifying individuals and group membership, as well as interspecific signaling.
Cho, Adrienne W, Coil, David A, Davis, Cristina E, Eisen, Jonathan A, Ganz, Holly H, Jospin, Guillaume, McCartney, Mitchell M, Yamaguchi, Mei S, Zaw, Thant H   +8 more
core   +1 more source

On the mechanism of Dehydroquinate synthase : a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science in Chemistry [PDF]

, 2001
The aim of this thesis is to investigate the influence of fluorine substitution on the second reaction of the shikimate pathway catalysed by the enzyme 3-dehydroquinate synthase.
Kathirgamanathan, Kalyani
core