Results 21 to 30 of about 21,035 (216)
Biotechnology for Biofuels, 2021 Background Hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT) is a central enzyme of the so-called “esters” pathway to monolignols. As originally envisioned, HCT functions twice in this pathway, to form coumaroyl shikimate and then, in ...
Juan Carlos Serrani-Yarce +6 more
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The acanthamoeba shikimate pathway has a unique molecular arrangement and is essential for aromatic amino acid biosynthesis [PDF]
, 2015 The shikimate pathway is the only known biosynthetic route for de novo synthesis of aromatic compounds. It is described as an ancient eukaryotic innovation that has been retained in a subset of eukaryotes, replaced in plants through the acquisition of ...
Campbell, Sara J. +5 more
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EPSP Synthase-Depleted Cells Are Aromatic Amino Acid Auxotrophs in Mycobacterium smegmatis
Microbiology Spectrum, 2021 The epidemiological importance of mycobacterial species is indisputable, and the necessity to find new molecules that can inhibit their growth is urgent.
Mario Alejandro Duque-Villegas +15 more
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Shikimate hydroxycinnamoyl transferase (HCT) activity assays in Populus nigra [PDF]
, 2013 Lignin is a complex phenolic polymer deposited in secondarily-thickened plant cell walls. The polymer is mainly derived from the three primary monolignols: p-coumaryl, coniferyl and sinapyl alcohol which give rise to p-hydroxyphenyl, guaiacyl and ...
Boerjan, Wout +4 more
core +2 more sources
Shikimate Metabolic Pathway Engineering in Corynebacterium glutamicum
Journal of Microbiology and Biotechnology, 2021 Shikimate is a key high-demand metabolite for synthesizing valuable antiviral drugs, such as the anti-influenza drug, oseltamivir (Tamiflu). Microbial-based strategies for shikimate production have been developed to overcome the unstable and expensive supply of shikimate derived from traditional plant extraction processes.
Park, Eunhwi +6 more
openaire +3 more sources
Systemic suppression of the shoot metabolism upon rice root nematode infection [PDF]
, 2014 Hirschmanniella oryzae is the most common plant-parasitic nematode in flooded rice cultivation systems. These migratory animals penetrate the plant roots and feed on the root cells, creating large cavities, extensive root necrosis and rotting.
Bauters, Lander +4 more
core +9 more sources
Microbial Cell Factories, 2017 Shikimate is an important intermediate in the aromatic amino acid pathway, which can be used as a promising building block for the synthesis of biological compounds, such as neuraminidase inhibitor Oseltamivir (Tamiflu®).
Pengfei Gu +4 more
doaj +1 more source
Nature Communications, 2023 Plant-sourced aromatic amino acid (AAA) derivatives are a vast group of compounds with broad applications. Here, we present the development of a yeast consortium for efficient production of (S)-norcoclaurine, the key precursor for benzylisoquinoline ...
Meirong Gao +5 more
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Synergetic engineering of Escherichia coli for efficient production of l-tyrosine
Synthetic and Systems Biotechnology, 2023 l-Tyrosine, an aromatic non-essential amino acid, is the raw material for many important chemical products, including levodopa, resveratrol, and hydroxytyrosol. It is widely used in the food, drug, and chemical industries.
Jurong Ping +4 more
doaj +1 more source
A 5-Enolpyruvylshikimate 3-Phosphate Synthase Functions as a Transcriptional Repressor in Populus. [PDF]
, 2018 Long-lived perennial plants, with distinctive habits of inter-annual growth, defense, and physiology, are of great economic and ecological importance.
Barros-Rios, Jaime +28 more
core +1 more source