Results 121 to 130 of about 478 (154)
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Effects of microbial elicitor on production of hypocrellin by Shiraia bambusicola
Folia Microbiologica, 2012Some endophyte isolates were isolated in a bamboo pole sample parasitized the fungus Shiraia bambusicola from Zhejiang Province. After screening through hypocrellin bacteriostatic effect and fermentation test, we got the isolate TX4 of bacterial elicitor and GZUIFR-TT1 of fungal elicitor which had certain effect to promote S.
Wen, Du +8 more
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Bamboo polysaccharides elicit hypocrellin A biosynthesis of a bambusicolous fungus Shiraia sp. S9
World Journal of Microbiology and Biotechnology, 2023Hypocrellin A (HA), a fungal perylenequinone from bambusicolous Shiraia species, is a newly developed photosensitizer for photodynamic therapy in cancer and other infectious diseases. The lower yield of HA is an important bottleneck for its biomedical application. This study is the first report of the enhancement of HA production in mycelium culture of
Wen Hao, Shen +6 more
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Phylogenetic study on Shiraia bambusicola by rDNA sequence analyses
Journal of Basic Microbiology, 2004AbstractIn this study, 18S rDNA and ITS‐5.8S rDNA regions of four Shiraia bambusicola isolates collected from different species of bamboos were amplified by PCR with universal primer pairs NS1/NS8 and ITS5/ITS4, respectively, and sequenced. Phylogenetic analyses were conducted on three selected datasets of rDNA sequences.
Tian-Fan, Cheng +4 more
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Improved hypocrellin A production in Shiraia bambusicola by light-dark shift
Journal of Photochemistry and Photobiology B: Biology, 2018Hypocrellin A (HA) is a major bioactive perylenequinone from the fruiting body of Shiraia bambusicola used for the treatment of skin diseases and developed as a photodynamic therapy (PDT) agent against cancers and viruses. The mycelial culture of S. bambusicola under dark is a biotechnological alternative for HA production but with low yield.
Chun Xiao, Sun +2 more
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Gentic overexpression increases production of hypocrellin A in Shiraia bambusicola S4201
Journal of Microbiology, 2019Hypocrellin A (HA) is a perylenequinone (PQ) isolated from Shiraia bambusicola that shows antiviral and antitumor activities, but its application is limited by the low production from wild fruiting body. A gene overexpressing method was expected to augment the production rate of HA in S. bambusicola.
Dan, Li +5 more
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High-efficiency biosynthesis of hypocrellin A in Shiraia sp. using gamma-ray mutagenesis
Applied Microbiology and Biotechnology, 2016Hypocrellin A (HA), well known as one of the best natural pigments and bioactive agent to treat skin diseases, is further anticipated to play a vital role in photodynamic therapy (PDT) in anticancer and antiviral treatments. In this study, an HA-producing strain ZZZ816 (Shiraia sp.) was isolated from the moso bamboo (Phyllostachys edulis) seeds, and ...
Hou Cheng-Lin, Xiao-Ye Shen
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Influences of light on growth, reproduction and hypocrellin production by Shiraia sp. SUPER-H168
Archives of Microbiology, 2018Light is a very important signal for fungi since it influences many different physiological responses. The effects of dark or light at different wavelengths on growth, reproduction and hypocrellins of Shiraia sp. SUPER-H168 were studied: dark, white, red, yellow, green, blue and purple.
Xiangru Liao +2 more
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Purification and characterization of a new laccase from Shiraia sp.SUPER-H168
Process Biochemistry, 2013Abstract A new laccase from Shiraia sp.SUPER-H168 was purified by ion exchange column chromatography and gel permeation chromatography and the apparent molecular mass of this enzyme was 70.78 kDa, as determined by MALDI/TOF-MS. The optimum pH value of the purified laccase was 4, 6, 5.5 and 3 with 2,6-dimethoxyphenol (DMP), syringaldazine, guaiacol ...
Yuchun Yang +3 more
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International Journal of Biological Macromolecules, 2020
Shiraia bambusicola exhibits an excellent capability to produce high-value pharmacological drugs, such as hypocrellin. However, less effective molecular tools hamper the processes to discover or exploit these metabolites. To address this issue, the more effective CRISPR/Cas9 system was constructed by optimizing the sgRNA transcription elements and ...
Huaxiang, Deng +4 more
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Shiraia bambusicola exhibits an excellent capability to produce high-value pharmacological drugs, such as hypocrellin. However, less effective molecular tools hamper the processes to discover or exploit these metabolites. To address this issue, the more effective CRISPR/Cas9 system was constructed by optimizing the sgRNA transcription elements and ...
Huaxiang, Deng +4 more
openaire +2 more sources
Journal of Basic Microbiology, 2022
AbstractShiraia bambusicola is a fungus with high economic value widely used in medicine, agriculture, and food. We wished to understand the genes and metabolites changes involved in the different developmental stages of S. bambusicola. So, to reveal key genes and metabolites in the main active metabolite, the were analyzed in different developmental ...
Xiyi Ren +6 more
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AbstractShiraia bambusicola is a fungus with high economic value widely used in medicine, agriculture, and food. We wished to understand the genes and metabolites changes involved in the different developmental stages of S. bambusicola. So, to reveal key genes and metabolites in the main active metabolite, the were analyzed in different developmental ...
Xiyi Ren +6 more
openaire +2 more sources