Results 71 to 80 of about 1,097,275 (327)

Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2020
Importance The combination of ascorbic acid, corticosteroids, and thiamine has been identified as a potential therapy for septic shock. Objective To determine whether the combination of ascorbic acid, corticosteroids, and thiamine attenuates organ ...
A. Moskowitz   +20 more
semanticscholar   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song   +6 more
wiley   +1 more source

Cutoff Values of Hemodynamic Parameters in Pediatric Refractory Septic Shock

open access: yesChildren, 2022
Background: Refractory septic shock can cause severe morbidities and mortalities in children. Resuscitation based on hemodynamics is important in children with critical illness.
En-Pei Lee   +5 more
doaj   +1 more source

A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]

open access: yes, 2012
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J   +2 more
core   +2 more sources

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

open access: yesArthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler   +8 more
wiley   +1 more source

Management and Outcome of Severe Sepsis and Septic Shock Patients

open access: yesJournal of Nepal Health Research Council, 2018
Background: Severe sepsis and septic shock are major causes of morbidity and mortality worldwide and need immediate medical attention. Early recognition, fluid resuscitation and early antimicrobials are the mainstays of sepsis therapy.
Sabitri Lamichhane   +3 more
doaj   +1 more source

Usefulness of ischemia-modified albumin in the diagnosis of sepsis/septic shock in the emergency department [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2020
Objective No studies have evaluated the diagnostic value of ischemia-modified albumin (IMA) for the early detection of sepsis/septic shock in patients presenting to the emergency department (ED).
Seung Hwa Choo   +6 more
doaj   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Diagnostic and Prognostic Significance of the Prothrombin Time/International Normalized Ratio in Sepsis and Septic Shock

open access: yesClinical and Applied Thrombosis/Hemostasis, 2022
Objective The study investigates the diagnostic and prognostic significance of the prothrombin time/international normalized ratio (PT/INR) in patients with sepsis and septic shock.
Tobias Schupp MD   +12 more
doaj   +1 more source

The prevalence of severe sepsis or septic shock in an Irish emergency department [PDF]

open access: yes, 2018
Severe sepsis and septic shock are among the leading causes of death globally. Despite the central role the emergency department (ED) plays in the early identification of patients presenting to hospital with sepsis, the prevalence of severe sepsis and ...
Fitzpatrick, Fidelma   +4 more
core  

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