Results 41 to 50 of about 45,602 (183)

Endocannabinoid dynamics gate spike-timing dependent depression and potentiation

eLife, 2016
Synaptic plasticity is a cardinal cellular mechanism for learning and memory. The endocannabinoid (eCB) system has emerged as a pivotal pathway for synaptic plasticity because of its widely characterized ability to depress synaptic transmission on short-
Yihui Cui, Ilya Prokin, Hao Xu, Bruno Delord, Stephane Genet, Laurent Venance, Hugues Berry   +6 more
doaj   +1 more source

The Antidepressant Sertraline Reduces Synaptic Transmission Efficacy and Synaptogenesis Between Identified Lymnaea Neurons

Frontiers in Marine Science, 2020
The incidence of depression among humans is growing worldwide, and so is the use of selective serotonin reuptake inhibitors (SSRIs), such as sertraline hydrochloride.
Jennifer Chow, Andrew J. Thompson, Andrew J. Thompson, Fahad Iqbal, Wali Zaidi, Naweed I. Syed, Naweed I. Syed   +6 more
doaj   +1 more source

Short‐term monocular deprivation alters early components of visual evoked potentials [PDF]

The Journal of Physiology, 2015
Key points Short‐term monocular deprivation in adult humans produces a perceptual boost of the deprived eye reflecting homeostatic plasticity. Visual evoked potentials (VEPs) to transient stimuli change after 150 min of monocular deprivation in adult humans.
LUNGHI, CLAUDIA, Berchicci, Marika, MORRONE, MARIA CONCETTA, Di Russo, Francesco   +3 more
openaire   +4 more sources

Programmable Electrofluidics for Ionic Liquid Based Neuromorphic Platform

Micromachines, 2019
Due to the limit in computing power arising from the Von Neumann bottleneck, computational devices are being developed that mimic neuro-biological processing in the brain by correlating the device characteristics with the synaptic weight of neurons. This
Walker L. Boldman, Cheng Zhang, Thomas Z. Ward, Dayrl P. Briggs, Bernadeta R. Srijanto, Philip Brisk, Philip D. Rack   +6 more
doaj   +1 more source

Multiplexed neurochemical transmission emulated using a dual-excitatory synaptic transistor

npj 2D Materials and Applications, 2021
The ability to emulate multiplexed neurochemical transmission is an important step toward mimicking complex brain activities. Glutamate and dopamine are neurotransmitters that regulate thinking and impulse signals independently or synergistically ...
Mingxue Ma, Yao Ni, Zirong Chi, Wanqing Meng, Haiyang Yu, Jiangdong Gong, Huanhuan Wei, Hong Han, Xinran Wang, Wentao Xu   +9 more
doaj   +1 more source

Age-related deficits in synaptic plasticity rescued by activating PKA or PKC in sensory neurons of Aplysia californica

Frontiers in Aging Neuroscience, 2015
Brain aging is associated with declines in synaptic function that contribute to memory loss, including reduced postsynaptic response to neurotransmitters and decreased neuronal excitability.
Andrew T Kempsell, Lynne A Fieber
doaj   +1 more source

Inositol hexakisphosphate kinase-1 is a key mediator of prepulse inhibition and short-term fear memory

Molecular Brain, 2020
Inositol phosphate metabolism has emerged as one of the key players in synaptic transmission. Previous studies have shown that the deletion of inositol hexakisphosphate kinase 1 (IP6K1), which is responsible for inositol pyrophosphate biosynthesis ...
Min-Gyu Kim, Seungjae Zhang, Hoyong Park, Seung Ju Park, Seyun Kim, ChiHye Chung   +5 more
doaj   +1 more source

Artificial Synapses Based on an Optical/Electrical Biomemristor

Nanomaterials, 2023
As artificial synapse devices, memristors have attracted widespread attention in the field of neuromorphic computing. In this paper, Al/polymethyl methacrylate (PMMA)/egg albumen (EA)–graphene quantum dots (GQDs)/PMMA/indium tin oxide (ITO) electrically ...
Lu Wang, Shutao Wei, Jiachu Xie, Yuehang Ju, Tianyu Yang, Dianzhong Wen   +5 more
doaj   +1 more source

Hippocampal network activity is transiently altered by induction of long-term potentiation in the dentate gyrus of freely behaving rats

Frontiers in Behavioral Neuroscience, 2007
A role for oscillatory activity in hippocampal neuronal networks has been proposed in sensory encoding, cognitive functions and synaptic plasticity.
Arthur Bikbaev, Denise Manahan-Vaughan, Denise Manahan-Vaughan   +2 more
doaj   +1 more source

Potential Short-Term Economic Benefits of Improved Glycemic Control [PDF]

Diabetes Care, 2001
OBJECTIVE— There are limited data relating glycemic control to medical costs among patients with diabetes. The goal of this study was to examine the potential impact of improved glycemic control on selected short-term complications of diabetes and associated costs in a managed care setting.
Joseph Menzin, Clare Langley-Hawthorne, Mark Friedman, Luke Boulanger, Robert Cavanaugh   +4 more
openaire   +1 more source