Results 61 to 70 of about 1,328,040 (201)

Multiplexed neurochemical transmission emulated using a dual-excitatory synaptic transistor

npj 2D Materials and Applications, 2021
The ability to emulate multiplexed neurochemical transmission is an important step toward mimicking complex brain activities. Glutamate and dopamine are neurotransmitters that regulate thinking and impulse signals independently or synergistically ...
Mingxue Ma, Yao Ni, Zirong Chi, Wanqing Meng, Haiyang Yu, Jiangdong Gong, Huanhuan Wei, Hong Han, Xinran Wang, Wentao Xu   +9 more
doaj   +1 more source

Age-related deficits in synaptic plasticity rescued by activating PKA or PKC in sensory neurons of Aplysia californica

Frontiers in Aging Neuroscience, 2015
Brain aging is associated with declines in synaptic function that contribute to memory loss, including reduced postsynaptic response to neurotransmitters and decreased neuronal excitability.
Andrew T Kempsell, Lynne A Fieber
doaj   +1 more source

Inositol hexakisphosphate kinase-1 is a key mediator of prepulse inhibition and short-term fear memory

Molecular Brain, 2020
Inositol phosphate metabolism has emerged as one of the key players in synaptic transmission. Previous studies have shown that the deletion of inositol hexakisphosphate kinase 1 (IP6K1), which is responsible for inositol pyrophosphate biosynthesis ...
Min-Gyu Kim, Seungjae Zhang, Hoyong Park, Seung Ju Park, Seyun Kim, ChiHye Chung   +5 more
doaj   +1 more source

A Mathematical model for Astrocytes mediated LTP at Single Hippocampal Synapses

, 2012
Many contemporary studies have shown that astrocytes play a significant role in modulating both short and long form of synaptic plasticity. There are very few experimental models which elucidate the role of astrocyte over Long-term Potentiation (LTP ...
A Araque, A Destexhe, AG Nikonenko, AL Hodgkin, AM Weber, AM Zhabotinsky, B Katz, B Mouillac, B Sahin, BL Bloodgood, BL Sabatini, BL Sabatini, C Agulhon, C Agulhon, C Fall, C Henneberger, C Koch, CLM Bon, D Dumitriu, D Sochivko, DJ Hagler Jr, DX Keller, E Neher, EB Malarkey, ER Higgins, F Erler, F Helmchen, F Taqatqeh, G Perea, GA Rameau, GL Collingridge, GW Young De, H-K Lee, HJ Koester, HV McCue, I Nikonenko, I Wenker, J Bai, J Boehm, J Garthwaite, J Kang, J Keener, J Lisman, J Marchaland, J Sneyd, J-W Shuai, JA Bibb, JE Lisman, JH Bollmann, JH Bollmann, JT Porter, Kaushik Majumdar, KD Micheva, KG Phillips, KM Franks, KT Blackwell, L-C Ching, L-Y Wang, LC Griffith, M Mazzanti, M Pittà De, M Tsodyks, MS Jafri, N Aslam, NC Danbolt, NJ Emptage, P Bezzi, P Miller, PP Atluri, R Anwyl, R Bertram, R Llinas, R Schneggenburger, R Schneggenburger, R Vargas, RA Hopper, RC Malenka, RF Fox, RP Munton, S Ben Achour, S Nadkarni, S Nadkarni, Shivendra Tewari, SJ Taylor, T Ishikawa, TA Fiacco, TP Jensen, TVP Bliss, TVP Bliss, V Calabrese, V Montana, V Parpura, V Parpura, V Volman, WT Coffey, Y Watanabe, Y-X Li, Z Nusser   +97 more
core   +1 more source

Protein kinase C is a calcium sensor for presynaptic short-term plasticity [PDF]

, 2014
In presynaptic boutons, calcium (Ca2+) triggers both neurotransmitter release and short-term synaptic plasticity. Whereas synaptotagmins are known to mediate vesicle fusion through binding of high local Ca2+ to their C2 domains, the proteins that sense ...
Chu, YunXiang, de Jong, Arthur PH, Fioravante, Diasynou, Kaeser, Pascal S, Leitges, Michael, Regehr, Wade G   +5 more
core   +3 more sources

Green's functions for reflectionless potentials and addition of boundstates to powerlaw potentials to find Supersymmetric partners [PDF]

arXiv, 2021
Green's functions for reflectionless potentials are constructed and analyzed. Green's functions for power law potentials, their Super Symmetric partners and sum rules for eigenvalues are examined. The SUSY partner potentials to power law potentials which have an additional bound state at $E=0$ are constructed.
arxiv  

A Mathematical Model of Tripartite Synapse: Astrocyte Induced Synaptic Plasticity

, 2012
In this paper we present a biologically detailed mathematical model of tripartite synapses, where astrocytes modulate short-term synaptic plasticity. The model consists of a pre-synaptic bouton, a post-synaptic dendritic spine-head, a synaptic cleft and ...
Majumdar, Kaushik, Tewari, Shivendra
core   +1 more source

Concentrations for nonlinear Schrodinger equation with magnetic potentials and constant electric potentials [PDF]

arXiv, 2022
This paper studies the concentration phenomena to nonlinear Schrodinger equations with magnetic potentials and constant electric potentials. We find that the magnetic field plays an important role in the location of concentrations if the electric potential is constant.
arxiv  

Optimal stimulation protocol in a bistable synaptic consolidation model

, 2018
Consolidation of synaptic changes in response to neural activity is thought to be fundamental for memory maintenance over a timescale of hours. In experiments, synaptic consolidation can be induced by repeatedly stimulating presynaptic neurons.
Gastaldi, Chiara, Gerstner, Wulfram, Muscinelli, Samuel P.   +2 more
core   +1 more source

Synaptic tagging and capture : differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation [PDF]

, 2010
Weakly tetanized synapses in area CA1 of the hippocampus that ordinarily display long-term potentiation lasting ~3 h (called early-LTP) will maintain a longer-lasting change in efficacy (late-LTP) if the weak tetanization occurs shortly before or after ...
Bito, Haruhiko, Frenguelli, Bruno G., Morris, R. G. M. (Richard G. M.), Okuno, Hiroyukki, Dr., Redondo, Roger L., Spooner, Patrick A.   +5 more
core   +2 more sources