Results 171 to 180 of about 187,730 (264)

Cognitive impairment in bipolar disorder associated with abnormal serum short-chain fatty acids and cytokines. [PDF]

BMC Psychiatry
Fan Y, Zhao B, Jia M, Qi Z, Gao Y, Wen B, Dong Y, Wang W, Feng J, Ma X, Ma Q.   +10 more
europepmc   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Deciphering the role of short-chain fatty acids (SCFAs) in diabetic nephropathy: protective or pathogenic mediators? [PDF]

Ann Med Surg (Lond)
Yaseen K, Khalid M, Asif A, Amin MHJ.
europepmc   +1 more source

Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression

Advanced Science, EarlyView.
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang, Tingting Tong, Pengxi Shi, Xiaofan Chen, Chenhao Wang, Qingyuan Weng, Sihan Chen, Linli Que, Qi Chen, Yuehua Li, Qiang Zhu, Jiantao Li   +11 more
wiley   +1 more source

Feasibility of Treating Eosinophilic Chronic Rhinosinusitis Using Short-Chain Fatty Acids. [PDF]

Laryngoscope
Gozawa R, Imoto Y, Sonoda Y, Maegawa A, Shimizu A, Kidoguchi M, Koyama K, Adachi N, Morikawa T, Miyazaki Y, Saito K, Sakashita M, Fujieda S.   +12 more
europepmc   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Commensal-derived short-chain fatty acids disrupt lipid membrane homeostasis in <i>Staphylococcus aureus</i>. [PDF]

mBio
Fletcher JR, Hansen LA, Hoyser JR, Hanna AE, Martinez R, Freeman CD, Thorns NT, Penningroth MR, Villarreal AR, Vogt GA, Tyler MA, Hines KM, Hunter RC.   +12 more
europepmc   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source

Members of Lachnospiraceae produce valerate and caproate in response to short-chain fatty acids. [PDF]

Microbiome
Fitzgerald BG, Govind M, Firth IJ, Herold L, Froment J, Vancuren SJ, Allen-Vercoe E, Kimber MS, Sorbara MT.   +8 more
europepmc   +1 more source