Results 121 to 130 of about 1,229,463 (349)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Short-term Fluctuations Of The Mesospheric Na Layer Observed By High-time-resolution Lidar
E3S Web of Conferences, 2018 Based on the 6-s resolution Na lidar measurements during ~395 hours on 47 different nights from May to November 2011 in Beijing(40.2°N, 116°E), China, it was found that the Na density at altitude 83-98 km always exhibited strong short-term fluctuations ...
Wang Xiaodong, Yi Fan
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The free energy cost of reducing noise while maintaining a high sensitivity
, 2015 Living systems need to be highly responsive, and also to keep fluctuations low. These goals are incompatible in equilibrium systems due to the Fluctuation Dissipation Theorem (FDT).
Sartori, Pablo, Tu, Yuhai
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Short range correlation of the erythrocyte membrane fluctuations [PDF]
, 2009 Luiza Buimagă-Iarinca, V. V. Morariu
openalex +1 more source
Superconducting fluctuations of the specific heat in the short wavelength fluctuation regime
Physics Procedia, 2012 AbstractEffects of the short wavelength fluctuations on the specific heat ΔC in a superconductor are studied within the scheme of the Aslamazov-Larkin (AL) theory. By imposing the momentum cutoff in the fluctuation spectrum, formulae for ΔC are derived in a layered system as well as in n-dimensional (nD) systems (n=1, 2 and 3).
Mori, N. +4 more
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
, 1999 It is natural for a Mott antiferromagnetism in RVB description to become a superconductor in doped metallic regime. But the issue of superconducting transition temperature is highly nontrivial, as the AF fluctuations in the form of RVB pair-breaking are ...
Weng, Z. Y.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source