Results 51 to 60 of about 8,064,980 (248)

MDL‐800–Induced Sirtuin 6 Activation Decreases Age‐Associated Osteoarthritis in Mice

Arthritis &Rheumatology, EarlyView.
Objective Sirtuin 6 (SIRT6) is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of MDL‐800, a small molecule activator of SIRT6, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez, Pranay Ramteke, Bahiyah Watson, Owen Haslam, Eirene Choi, Susan Chubinskaya, Mandy J. Peffers, William R. Davis, Jacqueline Shine, Brian O. Diekman, Richard F. Loeser, Theresa A. Freeman, Makarand V. Risbud, John A. Collins   +13 more
wiley   +1 more source

Comprehensive Analyses of the Strongly Carbon-chain Depleted Comets in Lowell Observatory’s Narrowband Photometry Database

The Planetary Science Journal
We present measurements, analyses, and results for the 17 strongly carbon-chain depleted comets in Lowell Observatory’s narrowband photometry database.
Allison N. Bair, David G. Schleicher
doaj   +1 more source

Application of Machine Learning Approaches in Electrophoresis—A Comprehensive Review

ELECTROPHORESIS, EarlyView.
This review paper highlights key research on the applications of machine learning tools in electrophoresis. ABSTRACT The electrophoretic technique is widely used to analyze and purify charged molecules based on their size, shape, and charge using an electric field for various applications, including DNA fingerprinting, genetic research, disease ...
Umaeer Al Hammad, Aminul Islam Khan, Prashanta Dutta   +2 more
wiley   +1 more source

Dust On, Dust Off: HST Observations of the Newly Dormant Jupiter Co-orbital Comet P/2023 V6 (PANSTARRS)

The Planetary Science Journal
As the Centaurs of the outer solar system have become better studied, their relationship with the Jupiter-family comets (JFCs) and their connection to the primordial protoplanetary disk have come under deeper scrutiny: which properties of the comets ...
John W. Noonan, Theodore Kareta
doaj   +1 more source

A survey of debris trails from short-period comets [PDF]

We observed 34 comets using the 24 micron camera on the Spitzer Space Telescope. Each image contains the nucleus and covers at least 10^6 km of each comet\u27s orbit.
Sykes, Mark V., Kelley, Michael S., Reach, William T.   +2 more
core   +1 more source

Is Ductal Carcinoma In Situ a Precursor or Low‐Risk Variant of Invasive Breast Cancer? A Population Perspective

International Journal of Cancer, EarlyView.
ABSTRACT Ductal carcinoma in situ (DCIS) is usually detected with mammography screening and assumed to be a precursor of invasive ductal cancer (IDC) of the breast. Yet, despite an approximately 10‐fold increase in the rate of DCIS detection and treatment within 20 years following implementation of mammography screening in the United States, IDC ...
Ismail Jatoi, Adalberto M. Filho, Gretchen Gierach, Hyuna Sung, Philip S. Rosenberg   +4 more
wiley   +1 more source

Comparing the reflectivity of ungrouped carbonaceous chondrites with those of short-period comets like 2P/Encke

, 2020
Aims. The existence of asteroid complexes produced by the disruption of these comets suggests that evolved comets could also produce high-strength materials able to survive as meteorites.
Trigo-Rodríguez, Josep María, Jordi Llorca, Jürgen Blum, Blum, Jürgen, Safoura Tanbakouei, Josep M. Trigo-Rodríguez, Tanbakouei, S., Williams, Iwan P., Iwan Williams, Llorca, Jordi, Llorca Piqué, Jordi   +10 more
core   +2 more sources

On the Motion of Short-Period Comets in the Neighbourhood of Jupiter [PDF]

Symposium - International Astronomical Union, 1972
An intermediate orbit is developed for studying the hyperbolic jovicentric motion of a comet in the vicinity of Jupiter, where the effect of Jupiter's oblateness may become significant. A comparison is made with some of the results obtained by other investigators on the motions of specific periodic comets.
openaire   +1 more source

Statistical and numerical studies of the orbital evolution of short-period comets [PDF]

International Astronomical Union Colloquium, 1985
AbstractThe evolutionary paths connecting cometary reservoirs in the outer solar system and the population of periodic comets involve stellar and planetary perturbations. Close planetary encounters play a special role, making the dynamical evolution slow or fast depending on the orbital elements of the comet at various stages of the process.
A. Carusi, G. B. Valsecchi
openaire   +1 more source

Nongravitational forces on comets [PDF]

, 1976
Methods are presented and discussed for determining the effects of nongravitational forces on the orbits of comets. These methods are applied to short-period and long-period comets.
Marsden, B. G.
core