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Profiling Short Tandem Repeats from Short Reads

2013
Short tandem repeats (STRs), also known as microsatellites, have a wide range of applications, including medical genetics, forensics, and population genetics. High-throughput sequencing has the potential to profile large numbers of STRs, but cumbersome gapped alignment and STR-specific noise patterns hamper this task. We recently developed an algorithm,
Melissa, Gymrek, Yaniv, Erlich
openaire   +2 more sources

A genomic view of short tandem repeats

Current Opinion in Genetics & Development, 2017
Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for accurately profiling STRs from high-throughput sequencing data have enabled genome-wide interrogation of more than a million STRs across hundreds of individuals.
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DNA Short Tandem Repeat Profiling of Morocco

Journal of Forensic Sciences, 2003
Abstract Blood samples were randomly collected on 186 unrelated males coming from all regions of Morocco. DNA was extracted using a Nucleon extraction kit (Amersham Life Science) and was genotyped with the Powerplex 16 kit (Promega) containing markers D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta
Alban, Jauffrit   +9 more
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The genomic landscape of short tandem repeats in cattle

Animal Genetics
AbstractShort tandem repeats (STRs) are abundant and have high mutation rates across cattle genomes; however, comprehensive exploration of cattle STRs is needed. Here, we constructed a comprehensive map of 467 553 polymorphic STRs (pSTRs) constructed from 423 cattle genomes representing 59 breeds worldwide.
Pengfei Wang   +8 more
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Short tandem repeat analysis in Japanese population

Electrophoresis, 2000
Short tandem repeats (STRs), known as microsatellites, are one of the most informative genetic markers for characterizing biological materials. Because of the relatively small size of STR alleles (generally 100-350 nucleotides), amplification by polymerase chain reaction (PCR) is relatively easy, affording a high sensitivity of detection.
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Instability of short tandem repeats (microsatellites) in human cancers

Nature Genetics, 1994
The allele sizes of polymorphic microsatellite repeats in DNA from human cancers were compared to normal DNA from the same patients. In 16 out of 196 paired samples (8%), we found evidence of an extra allele of a different size in the tumour which was not present in the normal DNA.
Wooster, R.   +12 more
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Short Tandem Repeat Analysis for Human Identity Testing

Current Protocols in Human Genetics, 2004
AbstractShort tandem repeat (STR) typing has become the workhorse of modern forensic DNA analysis. The most common form of STR typing uses laser‐induced fluorescence detection of dye‐labeled polymerase chain reaction (PCR) products following capillary electrophoresis (CE) size‐based separation. This unit describes the techniques and marker systems most
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Short tandem repeats and tandem repeat disorders

SCIENTIA SINICA Vitae
RunZe MA, TianCheng LIU, Bing ZHU
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Genetic analysis of 12 X-short tandem repeats loci in a northern Thai population

Medicine, Science and the Law, 2021
Supakit Khacha-Ananda
exaly  

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