Results 51 to 60 of about 65,971 (285)

RF: A method for filtering short reads with tandem repeats for genome mapping

, 2013
Next-generation sequencing platforms generate short (50–150bp) reads that can be mapped onto the reference genome. Repetitive sequences in the genome, because of the presence of similar or identical sequences, cause mapping errors in the case of the ...
Misawa, Kazuharu
core   +1 more source

NanoRepeat: quantification of Short Tandem Repeats (STRs) from Oxford Nanopore sequencing data

, 2022
NanoRepeat is a software tool for quantification of Short Tandem Repeats (STRs) from Oxford Nanopore sequencing data. The software is released under the MIT License For more information, please visit the GitHub repository: https://github.com/WGLab ...
Fang, Li, Wang, Kai
core   +1 more source

Comprehensive Insights Into Forensic Features and Genetic Background of Chinese Northwest Hui Group Using Six Distinct Categories of 231 Molecular Markers

Frontiers in Genetics, 2021
The Hui minority is predominantly composed of Chinese-speaking Islamic adherents distributed throughout China, of which the individuals are mainly concentrated in Northwest China.
Chong Chen, Chong Chen, Xiaoye Jin, Xingru Zhang, Xingru Zhang, Wenqing Zhang, Yuxin Guo, Ruiyang Tao, Anqi Chen, Anqi Chen, Qiannan Xu, Qiannan Xu, Min Li, Min Li, Yue Yang, Yue Yang, Bofeng Zhu, Bofeng Zhu, Bofeng Zhu   +18 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

An efficient algorithm for finding short approximate non-tandem repeats

, 2001
We study the problem of approximate non-tandem repeat †extraction. Given a long subject string S of length N over a finite alphabet Σ and a threshold D, we would like to find all short substrings of S of length P that repeat with at most D differences, i.
Tao Jiang, Michael Kaufmann, Ezekiel F. Adebiyi   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Mutational dynamics of short tandem repeats in human genome

, 2004
The evolutionary dynamics of short tandem repeats of nucleotide sequences of the human genome is studied. It is shown that a model due to which the evolutionary repeat dynamics consists of elongations and shortenings of the repeats, combined with point ...
B. Borštnik, D. Pumpernik
core   +1 more source

ExpansionHunter Denovo: a suite of tools for detecting novel expansions of short tandem repeats

, 2020
ExpansionHunter Denovo (EHdn) is a suite of tools for detecting novel expansions of short tandem repeats. EHdn is intended for analysis of a collection of BAM/CRAM files containing alignments of short (100-200bp ...
Lajoie, Bryan, Scherer, Stephen, Dolzhenko, Egor, Wasserman, Wyeth, Bennett, Mark, Trost, Brett, Nguyen, Charlotte, Bahlo, Melanie, Chen, Sai, Bentley, David, Taft, Ryan, Richmond, Phillip, Eberle, Michael, Narzisi, Giuseppe, van Vugt, Joke, Gainullin, Vladimir, Gross, Andrew, Veldink, Jan, Yuen, Ryan   +18 more
core   +1 more source

Dataset of 21 autosomal short tandem repeats in the population of Sardinia

, 2021
In this dataset we provide, for the first time, allele frequencies of 21 autosomal short tandem repeats (STRs) on a sample of 500 individuals, both male and female, from Sardinian population (Italy)
Calo, C (via Mendeley Data)
core   +1 more source

Short tandem repeats genotyping of gestational choriocarcinoma – our experiences

Taiwanese Journal of Obstetrics & Gynecology
Objective: This short communication demonstrates how short tandem repeat genotyping can identify the origin of gestational choriocarcinoma. Materials and methods: The origin of gestational choriocarcinoma in our three cases was determined using the short
Lajos Gergely, Vanda Repiska, Robert Petrovic, Miroslav Korbel, Ludovit Danihel, Jozef Sufliarsky, Michaela Kubickova, Helena Gbelcova, Petra Priscakova   +8 more
doaj   +1 more source