Results 41 to 50 of about 144,950 (282)

The challenge of small-scale repeats for indel discovery

Frontiers in Bioengineering and Biotechnology, 2015
Repetitive sequences are abundant in the human genome. Different classes of repetitive DNA sequences, including simple repeats, tandem repeats, segmental duplications, interspersed repeats and other elements, collectively span more than 50% of the genome.
Giuseppe eNarzisi, Michael C Schatz
doaj   +1 more source

Multiple Locus Variable number of tandem repeat Analysis : a molecular genotyping tool for Paenibacillus larvae [PDF]

, 2016
American Foulbrood, caused by Paenibacillus larvae, is the most severe bacterial disease of honey bees (Apis mellifera). To perform genotyping of P.larvae in an epidemiological context, there is a need of a fast and cheap method with a high resolution ...
Alippi, Alippi, Antunez, Ash, Ash, Bassi, Belkum, Belkum, Buhlmann, Bui, Chan, Djordjevic, Djukic, Dobbelaere, Gelfand, Genersch, Genersch, Genersch, Genersch, Girard, Graaf, Graaf, Heyndrickx, Katznelson, Klevytska, Lindstedt, Lindstrom, Lindstrom, Loncaric, Malachowa, Mazars, Morrissey, Neuendorf, Qin, Schafer, Stratilo, Techaruvichit, Torres-Cruz, U'Ren, Vogler, Wu   +40 more
core   +2 more sources

Inferring short tandem repeat variation from paired-end short reads [PDF]

Nucleic Acids Research, 2013
The advances of high-throughput sequencing offer an unprecedented opportunity to study genetic variation. This is challenged by the difficulty of resolving variant calls in repetitive DNA regions. We present a Bayesian method to estimate repeat-length variation from paired-end sequence read data.
Cao, Minh Duc, Tasker, Edward, Willadsen, Kai, Imelfort, Michael, Vishwanathan, Sailaja, Sureshkumar, Sridevi, Balasubramanian, Sureshkumar, Bodén, Mikael   +7 more
openaire   +3 more sources

Short Tandem Repeats (STR) in cattle genomics and breeding [PDF]

Biotechnology in Animal Husbandry, 2018
Molecular markers are essential tool for determining the specific genetic makeup of an individual and are valuable approach for genetic improvement of farm animals.
Teneva Atanaska, Todorovska Elena, Petrović Milan P., Kusza Szilvia, Perriassamy Kathiravan, Caro-Petrović Violeta, Ostojić-Andrić Dušica, Gadjev Dimitar   +7 more
doaj  

Measuring microsatellite conservation in mammalian evolution with a phylogenetic birth-death model. [PDF]

, 2012
Microsatellites make up ∼3% of the human genome, and there is increasing evidence that some microsatellites can have important functions and can be conserved by selection.
Buschiazzo, Emmanuel, Gemmell, Neil, Lennon, Dustin, Minin, Vladimir N, Sawaya, Sterling M   +4 more
core   +1 more source

Link between short tandem repeats and translation initiation site selection

Human Genomics, 2018
Background Despite their vast biological implication, the relevance of short tandem repeats (STRs)/microsatellites to the protein-coding gene translation initiation sites (TISs) remains largely unknown.
Masoud Arabfard, Kaveh Kavousi, Ahmad Delbari, Mina Ohadi   +3 more
doaj   +1 more source

Core promoter short tandem repeats as evolutionary switch codes for primate speciation [PDF]

, 2015
Alteration in gene expression levels underlies many of the phenotypic differences across species. Because of their highly mutable nature, proximity to the +1 transcription start site (TSS), and the emerging evidence of functional impact on gene ...
Bagheri, A., Darvish, H., Ghadimi-Haddadan, S., Kazeminasab, S., Kowsari, A., Namdar-Aligoodarzi, P., Ohadi, M., Rezazadeh, M., Valipour, E.   +8 more
core  

Indels, structural variation, and recombination drive genomic diversity inPlasmodium falciparum [PDF]

, 2016
The malaria parasite Plasmodium falciparum has a great capacity for evolutionary adaptation to evade host immunity and develop drug resistance. Current understanding of parasite evolution is impeded by the fact that a large fraction of the genome is ...
Campino, Susana, Drury, Eleanor, Ferdig, Michael, Gould, Kelda, Hayton, Karen, Iqbal, Zamin, Kwiatkowski, Dominic, MacInnis, Bronwyn, McVean, Gil, Mead, Daniel, Miles, Alistair, Mwangi, Jonathan, O'Brien, John, Pearson, Richard, Ranford-Cartwright, Lisa, Rayner, Julian, Ruano Rubio, Valentin, Samarakoon, Upeka, Su, Xin-zhuan, Theron, Michel, Vauterin, Paul, Wellems, Thomas   +21 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Comprehensive Insights Into Forensic Features and Genetic Background of Chinese Northwest Hui Group Using Six Distinct Categories of 231 Molecular Markers

Frontiers in Genetics, 2021
The Hui minority is predominantly composed of Chinese-speaking Islamic adherents distributed throughout China, of which the individuals are mainly concentrated in Northwest China.
Chong Chen, Chong Chen, Xiaoye Jin, Xingru Zhang, Xingru Zhang, Wenqing Zhang, Yuxin Guo, Ruiyang Tao, Anqi Chen, Anqi Chen, Qiannan Xu, Qiannan Xu, Min Li, Min Li, Yue Yang, Yue Yang, Bofeng Zhu, Bofeng Zhu, Bofeng Zhu   +18 more
doaj   +1 more source