Results 41 to 50 of about 3,537,585 (186)

Profiling the Genome-Wide Landscape of Short Tandem Repeats by Long-Read Sequencing

Frontiers in Genetics, 2022
Background: Short tandem repeats (STRs) are highly variable elements that play a pivotal role in multiple genetic diseases and the regulation of gene expression. Long-read sequencing (LRS) offers a potential solution to genome-wide STR analysis. However,
Zhenhua Liu, Guihu Zhao, Yuhui Xiao, Sheng Zeng, Yanchun Yuan, Xun Zhou, Zhenghuan Fang, Runcheng He, Bin Li, Yuwen Zhao, Hongxu Pan, Yige Wang, Guoliang Yu, I-Feng Peng, Depeng Wang, Qingtuan Meng, Qian Xu, Qiying Sun, Xinxiang Yan, Lu Shen, Lu Shen, Hong Jiang, Hong Jiang, Kun Xia, Junling Wang, Jifeng Guo, Fan Liang, Jinchen Li, Jinchen Li, Jinchen Li, Beisha Tang, Beisha Tang, Beisha Tang, Beisha Tang   +33 more
doaj   +1 more source

Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory complexes [PDF]

, 2010
peer-reviewedBackground: About forty human diseases are caused by repeat instability mutations. A distinct subset of these diseases is the result of extreme expansions of polymorphic trinucleotide repeats; typically CAG repeats encoding poly-glutamine ...
Herman Raadsma, Raadsma Herman, Lynn David J, Hobbs, Matthew, Whan Vicki, McWilliam, Sean, Lynn, David J, Tellam, Ross L, Barendse William, Tellam Ross L, Ross L Tellam, Vicki Whan, McWilliam Sean, Khatkar Mehar, Lutzow Ylva, David J Lynn, William Barendse, Ylva Lutzow, Whan, Vicki, Khatkar, Mehar, Raadsma, Herman, Tellam, Ross L., Ylva Strandberg Lutzow, Barendse, William, Lutzow, Ylva Strandberg, Sean McWilliam, Lynn, David J., Lutzow, Ylva S, Matthew Hobbs, Hobbs Matthew, Mehar Khatkar   +30 more
core   +1 more source

The challenge of small-scale repeats for indel discovery

Frontiers in Bioengineering and Biotechnology, 2015
Repetitive sequences are abundant in the human genome. Different classes of repetitive DNA sequences, including simple repeats, tandem repeats, segmental duplications, interspersed repeats and other elements, collectively span more than 50% of the genome.
Giuseppe eNarzisi, Michael C Schatz
doaj   +1 more source

Multiple-locus variable-number tandem-repeat analysis of the swine dysentery pathogen, Brachyspira hyodysenteriae [PDF]

, 2010
The spirochete Brachyspira hyodysenteriae is the causative agent of swine dysentery, a severe colonic infection of pigs that has a considerable economic impact in many swine-producing countries.
Rubio, P., Phillips, N.D., Ana Carvajal, Hidalgo, A., Germán Naharro, Tom La, Hampson, D.J., Álvaro Hidalgo, Pedro Rubio, Carvajal, A., La, T., David J. Hampson, Naharro, G., Nyree D. Phillips   +13 more
core   +1 more source

Short Tandem Repeats (STR) in cattle genomics and breeding [PDF]

Biotechnology in Animal Husbandry, 2018
Molecular markers are essential tool for determining the specific genetic makeup of an individual and are valuable approach for genetic improvement of farm animals.
Teneva Atanaska, Todorovska Elena, Petrović Milan P., Kusza Szilvia, Perriassamy Kathiravan, Caro-Petrović Violeta, Ostojić-Andrić Dušica, Gadjev Dimitar   +7 more
doaj  

Link between short tandem repeats and translation initiation site selection

Human Genomics, 2018
Background Despite their vast biological implication, the relevance of short tandem repeats (STRs)/microsatellites to the protein-coding gene translation initiation sites (TISs) remains largely unknown.
Masoud Arabfard, Kaveh Kavousi, Ahmad Delbari, Mina Ohadi   +3 more
doaj   +1 more source

Comprehensive Insights Into Forensic Features and Genetic Background of Chinese Northwest Hui Group Using Six Distinct Categories of 231 Molecular Markers

Frontiers in Genetics, 2021
The Hui minority is predominantly composed of Chinese-speaking Islamic adherents distributed throughout China, of which the individuals are mainly concentrated in Northwest China.
Chong Chen, Chong Chen, Xiaoye Jin, Xingru Zhang, Xingru Zhang, Wenqing Zhang, Yuxin Guo, Ruiyang Tao, Anqi Chen, Anqi Chen, Qiannan Xu, Qiannan Xu, Min Li, Min Li, Yue Yang, Yue Yang, Bofeng Zhu, Bofeng Zhu, Bofeng Zhu   +18 more
doaj   +1 more source

Primers and Short Tandem Repeats genomic position.

, 2015
Primers and Short Tandem Repeats genomic position.
Pierre Hainaut (15065), Juliana Giacomazzi (128241), Rui Manoel Reis (831638), Sidney Emanuel Batista dos Santos (187708), Diego Davila Paskulin (831636), Patricia Ashton-Prolla (128262), Maria Isabel Achatz (831637), Sandra Costa (455401)   +7 more
core   +1 more source

lobSTR: A Short Tandem Repeat Profiler for Personal Genomes [PDF]

Genome Research, 2012
Short tandem repeats (STRs) have a wide range of applications, including medical genetics, forensics, and genetic genealogy. High-throughput sequencing (HTS) has the potential to profile hundreds of thousands of STR loci. However, mainstream bioinformatics pipelines are inadequate for the task.
Melissa Gymrek, David Golan, Saharon Rosset, Yaniv Erlich   +3 more
openaire   +2 more sources

Short tandem repeats genotyping of gestational choriocarcinoma – our experiences

Taiwanese Journal of Obstetrics & Gynecology
Objective: This short communication demonstrates how short tandem repeat genotyping can identify the origin of gestational choriocarcinoma. Materials and methods: The origin of gestational choriocarcinoma in our three cases was determined using the short
Lajos Gergely, Vanda Repiska, Robert Petrovic, Miroslav Korbel, Ludovit Danihel, Jozef Sufliarsky, Michaela Kubickova, Helena Gbelcova, Petra Priscakova   +8 more
doaj   +1 more source