Results 31 to 40 of about 144,950 (282)

Short tandem repeat polymorphism evolution in humans [PDF]

European Journal of Human Genetics, 1998
Forty-five dinucleotide short tandem repeat polymorphisms were typed in ten large samples of a globally distributed set of populations. Although these markers had been selected for high heterozygosity in European populations, we found them to be sufficiently informative for linkage analysis in non-Europeans.
F, Calafell, A, Shuster, W C, Speed, J R, Kidd, K K, Kidd   +4 more
openaire   +2 more sources

Relatively semi-conservative replication and a folded slippage model for short tandem repeats

BMC Genomics, 2020
Background The ubiquitous presence of short tandem repeats (STRs) in virtually all genomes implicates their functional relevance, while a widely-accepted definition of STR is yet to be established. Previous studies majorly focus on relatively longer STRs,
Hongxi Zhang, Douyue Li, Xiangyan Zhao, Saichao Pan, Xiaolong Wu, Shan Peng, Hanrou Huang, Ruixue Shi, Zhongyang Tan   +8 more
doaj   +1 more source

Retrospective cell lineage reconstruction in humans by using short tandem repeats

Cell Reports: Methods, 2021
Summary: Cell lineage analysis aims to uncover the developmental history of an organism back to its cell of origin. Recently, novel in vivo methods utilizing genome editing enabled important insights into the cell lineages of animals.
Liming Tao, Ofir Raz, Zipora Marx, Manjusha S. Ghosh, Sandra Huber, Julia Greindl-Junghans, Tamir Biezuner, Shiran Amir, Lilach Milo, Rivka Adar, Ron Levy, Amos Onn, Noa Chapal-Ilani, Veronika Berman, Asaf Ben Arie, Guy Rom, Barak Oron, Ruth Halaban, Zbigniew T. Czyz, Melanie Werner-Klein, Christoph A. Klein, Ehud Shapiro   +21 more
doaj   +1 more source

Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS Complex

Cell Reports, 2016
Summary: Tandem repetitive DNA is highly abundant in eukaryotic genomes and contributes to transcription control and genome stability. However, how the individual sequences within tandem repeats behave remains largely unknown.
Haijin He, Shu Zhang, Danni Wang, Andreas Hochwagen, Fei Li   +4 more
doaj   +1 more source

Profiling the Genome-Wide Landscape of Short Tandem Repeats by Long-Read Sequencing

Frontiers in Genetics, 2022
Background: Short tandem repeats (STRs) are highly variable elements that play a pivotal role in multiple genetic diseases and the regulation of gene expression. Long-read sequencing (LRS) offers a potential solution to genome-wide STR analysis. However,
Zhenhua Liu, Guihu Zhao, Yuhui Xiao, Sheng Zeng, Yanchun Yuan, Xun Zhou, Zhenghuan Fang, Runcheng He, Bin Li, Yuwen Zhao, Hongxu Pan, Yige Wang, Guoliang Yu, I-Feng Peng, Depeng Wang, Qingtuan Meng, Qian Xu, Qiying Sun, Xinxiang Yan, Lu Shen, Lu Shen, Hong Jiang, Hong Jiang, Kun Xia, Junling Wang, Jifeng Guo, Fan Liang, Jinchen Li, Jinchen Li, Jinchen Li, Beisha Tang, Beisha Tang, Beisha Tang, Beisha Tang   +33 more
doaj   +1 more source

The mitochondrial genome of the venomous cone snail conus consors [PDF]

, 2012
Cone snails are venomous predatory marine neogastropods that belong to the species-rich superfamily of the Conoidea. So far, the mitochondrial genomes of two cone snail species (Conus textile and Conus borgesi) have been described, and these feed on ...
Baden-Tillson, Holly, Brauer, Age, Heidler, Juliana, Kauferstein, Silke, Kurz, Alexander, Mebs, Dietrich, Remm, Maido, Stockwell, Tim, Stöcklin, Reto, Wittig, Ilka   +9 more
core   +3 more sources

Hot and crispy : CRISPR-Cas systems in the hyperthermophile Sulfolobus solfataricus [PDF]

, 2013
The CRISPR (clustered regularly interspaced short palindromic repeats) and Cas (CRISPR-associated) genes are widely spread in bacteria and archaea, representing an intracellular defence system against invading viruses and plasmids.
White, Malcolm F., Zhang, Jing
core   +2 more sources

Genetic investigation of the origin of an allograft ureteral carcinoma with short tandem repeats: From recipient or donor?

Urological Science, 2023
Purpose: The purpose of this study was to demonstrate the usefulness of genetic analysis with short tandem repeats (STRs) to identify the cellular origin of an unusual allograft urothelial carcinoma (UC).
Jia-Yuh Sheu, Jeff Shih-Chieh Chueh, Chao-Yuan Huang, Hsiao-Lin Hwa, Shuo-Meng Wang   +4 more
doaj   +1 more source

Detection and diversity of a putative novel heterogeneous polymorphic proline-glycine repeat (Pgr) protein in the footrot pathogen Dichelobacter nodosus [PDF]

, 2010
Dichelobacter nodosus, a Gram-negative anaerobic bacterium, is the essential causative agent of footrot in sheep. Currently, depending on the clinical presentation in the field, footrot is described as benign or virulent; D.
Atiya Ul-Hassan, Buller, Bzymek, Cheetham, Claire L. Russell, Claxton, Depiazzi, Elizabeth M.H. Wellington, Girard, Graham F. Medley, Gravekamp, Gravekamp, Heise, Hindmarsh, Jasmeet Kaler, Jelinek, Jordan, Julian I. Rood, Katz, Katz, Kay, Kennan, Kennan, La Fontaine, Ladefoged, Laura E. Green, Leo A. Calvo-Bado, Lukomski, Madoff, Moore, Myers, Nallapareddy, Nicky Buller, O’Dushlaine, Palmer, Paterson, Pringle, Puopolo, Rasmussen, Romero, Rood, Rose Grogono-Thomas, Ruth M. Kennan, Vanhoof, Verstrepen, Williamson, Yong, Zhang   +47 more
core   +4 more sources

PERGA: A Paired-End Read Guided De Novo Assembler for Extending Contigs Using SVM and Look Ahead Approach [PDF]

, 2014
Since the read lengths of high throughput sequencing (HTS) technologies are short, de novo assembly which plays significant roles in many applications remains a great challenge. Most of the state-of-the-art approaches base on de Bruijn graph strategy and
Chin, FYL, Leung, HCM, Liu, B, Quan, G, Wang, Y, Yiu, SM, Zhu, X   +6 more
core   +3 more sources