Results 31 to 40 of about 65,971 (285)

Short tandem repeats bind transcription factors to tune eukaryotic gene expression

, 2023
Short tandem repeats bind transcription factors to tune eukaryotic gene expression.
Connor Horton
core   +1 more source

Genotypes of the three isolated clinical strains as determined using transfer RNA-linked short tandem repeats.

, 2022
Genotypes of the three isolated clinical strains as determined using transfer RNA-linked short tandem repeats.
Shinji Izumiyama (10013539), Koji Watanabe (205444), Yumiko Saito-Nakano (1842100), Yasuaki Yanagawa (3590654), Seiki Kobayashi (467790), Yoshimi Kikuchi (212497), Hiroyuki Gatanaga (205448), Tomoyoshi Nozaki (131314), Naoko Yoshida (790080), Shinichi Oka (205454), Kumiko Nakada-Tsukui (181460)   +10 more
core   +1 more source

A Brief Review of Short Tandem Repeat Mutation

Genomics, Proteomics & Bioinformatics, 2007
Abstract Short tandem repeats (STRs) are short tandemly repeated DNA sequences that involve a repetitive unit of 1–6 bp. Because of their polymorphisms and high mutation rates, STRs are widely used in biological research. Strand-slippage replication is the predominant mutation mechanism of STRs, and the stepwise mutation model is ...
Hao Fan, Jia-You Chu
openaire   +2 more sources

Relatively semi-conservative replication and a folded slippage model for short tandem repeats

BMC Genomics, 2020
Background The ubiquitous presence of short tandem repeats (STRs) in virtually all genomes implicates their functional relevance, while a widely-accepted definition of STR is yet to be established. Previous studies majorly focus on relatively longer STRs,
Hongxi Zhang, Douyue Li, Xiangyan Zhao, Saichao Pan, Xiaolong Wu, Shan Peng, Hanrou Huang, Ruixue Shi, Zhongyang Tan   +8 more
doaj   +1 more source

Retrospective cell lineage reconstruction in humans by using short tandem repeats

Cell Reports: Methods, 2021
Summary: Cell lineage analysis aims to uncover the developmental history of an organism back to its cell of origin. Recently, novel in vivo methods utilizing genome editing enabled important insights into the cell lineages of animals.
Liming Tao, Ofir Raz, Zipora Marx, Manjusha S. Ghosh, Sandra Huber, Julia Greindl-Junghans, Tamir Biezuner, Shiran Amir, Lilach Milo, Rivka Adar, Ron Levy, Amos Onn, Noa Chapal-Ilani, Veronika Berman, Asaf Ben Arie, Guy Rom, Barak Oron, Ruth Halaban, Zbigniew T. Czyz, Melanie Werner-Klein, Christoph A. Klein, Ehud Shapiro   +21 more
doaj   +1 more source

Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS Complex

Cell Reports, 2016
Summary: Tandem repetitive DNA is highly abundant in eukaryotic genomes and contributes to transcription control and genome stability. However, how the individual sequences within tandem repeats behave remains largely unknown.
Haijin He, Shu Zhang, Danni Wang, Andreas Hochwagen, Fei Li   +4 more
doaj   +1 more source

Profiling the Genome-Wide Landscape of Short Tandem Repeats by Long-Read Sequencing

Frontiers in Genetics, 2022
Background: Short tandem repeats (STRs) are highly variable elements that play a pivotal role in multiple genetic diseases and the regulation of gene expression. Long-read sequencing (LRS) offers a potential solution to genome-wide STR analysis. However,
Zhenhua Liu, Guihu Zhao, Yuhui Xiao, Sheng Zeng, Yanchun Yuan, Xun Zhou, Zhenghuan Fang, Runcheng He, Bin Li, Yuwen Zhao, Hongxu Pan, Yige Wang, Guoliang Yu, I-Feng Peng, Depeng Wang, Qingtuan Meng, Qian Xu, Qiying Sun, Xinxiang Yan, Lu Shen, Lu Shen, Hong Jiang, Hong Jiang, Kun Xia, Junling Wang, Jifeng Guo, Fan Liang, Jinchen Li, Jinchen Li, Jinchen Li, Beisha Tang, Beisha Tang, Beisha Tang, Beisha Tang   +33 more
doaj   +1 more source

Short tandem repeat polymorphism evolution in humans [PDF]

European Journal of Human Genetics, 1998
Forty-five dinucleotide short tandem repeat polymorphisms were typed in ten large samples of a globally distributed set of populations. Although these markers had been selected for high heterozygosity in European populations, we found them to be sufficiently informative for linkage analysis in non-Europeans.
F, Calafell, A, Shuster, W C, Speed, J R, Kidd, K K, Kidd   +4 more
openaire   +2 more sources

Tandem repeat copy-number variation in protein-coding regions of human genes

, 2005
BACKGROUND: Tandem repeat variation in protein-coding regions will alter protein length and may introduce frameshifts. Tandem repeat variants are associated with variation in pathogenicity in bacteria and with human disease.
O'Dushlaine, Colm T., Edwards, Richard, Park, Stephen D., Richard J Edwards, Colm T O'Dushlaine, Denis C Shields, Shields, Denis C., Stephen D Park   +7 more
core   +1 more source

Finding long tandem repeats in long noisy reads.

, 2021
Long tandem repeat expansions of more than 1000 nt have been suggested to be associated with diseases, but remain largely unexplored in individual human genomes because read lengths have been too short.
Ichikawa, K., Morishita, S., Myers, E.
core   +1 more source