Results 11 to 20 of about 144,950 (282)

Genotyping short tandem repeats across copy number alterations, aneuploidies, and polyploid organisms [PDF]

Communications Biology
Short tandem repeats (STRs) are a rich source of genetic variation, but are difficult to genotype. While specialized repeat variant callers exist, they typically assume a euploid human genome.
Max A. Verbiest, Elena Grassi, Andrea Bertotti, Maria Anisimova   +3 more
doaj   +3 more sources

Natural variation in C. elegans short tandem repeats. [PDF]

Genome Res, 2022
Short tandem repeats (STRs) represent an important class of genetic variation that can contribute to phenotypic differences. Although millions of single nucleotide variants (SNVs) and short indels have been identified among wild Caenorhabditis elegans strains, the natural diversity in STRs ...
Zhang G, Wang Y, Andersen EC.
europepmc   +3 more sources

Modification of Huntington's disease by short tandem repeats. [PDF]

Brain Commun
Abstract Expansions of glutamine-coding CAG trinucleotide repeats cause a number of neurodegenerative diseases, including Huntington’s disease and several of spinocerebellar ataxias. In general, age-at-onset of the polyglutamine diseases is inversely correlated with the size of the respective inherited expanded CAG repeat.
Hong EP, Ramos EM, Aziz NA, Massey TH, McAllister B, Lobanov S, Jones L, Holmans P, Kwak S, Orth M, Ciosi M, Lomeikaite V, Monckton DG, Long JD, Lucente D, Wheeler VC, Gillis T, MacDonald ME, Sequeiros J, Gusella JF, Lee JM.   +20 more
europepmc   +4 more sources

Evaluation of allelic alterations in short tandem repeats in papillary thyroid cancer

Molecular Genetics & Genomic Medicine, 2020
Background Malignant tissue samples may be the only source of biological material for forensic investigations, including individual identification or paternity testing; however, such samples may lead to uncertainties due to frequent genomic aberrations ...
Zhen Dang, Lu Li, Xia Kong, Guoan Zhang, Qi Liu, Haibin Li, Liang Li, Renya Zhang, Wen Cui, Yequan Wang   +9 more
doaj   +2 more sources

Polymorphic short tandem repeats make widespread contributions to blood and serum traits. [PDF]

Cell Genom, 2023
Margoliash J, Fuchs S, Li Y, Zhang X, Massarat A, Goren A, Gymrek M.   +6 more
europepmc   +2 more sources

Structural variants and short tandem repeats impact gene expression and splicing in bovine testis tissue. [PDF]

Genetics, 2023
Bhati M, Mapel XM, Lloret-Villas A, Pausch H.   +3 more
europepmc   +3 more sources

Author Correction: Short tandem repeats delineate gene bodies across eukaryotes [PDF]

Nature Communications
William B. Reinar, Anders K. Krabberød, Vilde O. Lalun, Melinka A. Butenko, Kjetill S. Jakobsen   +4 more
doaj   +2 more sources

Counting short tandem repeats [PDF]

Nature Methods, 2020
A method using CRISPR–Cas technology, nanopore sequencing and bioinformatics enables quantification of short tandem repeats with high accuracy.
openaire   +2 more sources

Analysis of short tandem repeats by parallel DNA threading. [PDF]

PLoS ONE, 2009
The majority of studies employing short tandem repeats (STRs) require investigation of several of these genetic markers. As such, we demonstrate the feasibility of the trinucleotide threading (TnT) approach for scalable analysis of STRs.
Pawel Zajac, Christine Oberg, Afshin Ahmadian   +2 more
doaj   +1 more source

Short Tandem Repeats in plants: Genomic distribution and function prediction

Electronic Journal of Biotechnology, 2021
Background: Short Tandem repeats (STRs) existed as popular elements in both eukaryotic and prokaryotic genomes. Results: In this study, we analyzed the characteristics, distributions, and motif features of STRs within whole-genomes of 140 plant species ...
Lin Zhu, Hui Wu, Huayang Li, Heng Tang, Li Zhang, Houjuan Xu, Fangchan Jiao, Nian Wang, Long Yang   +8 more
doaj   +1 more source