Results 71 to 80 of about 144,950 (282)
STRScan: targeted profiling of short tandem repeats in whole-genome sequencing data
BMC Bioinformatics, 2017 Background Short tandem repeats (STRs) are found in many prokaryotic and eukaryotic genomes, and are commonly used as genetic markers, in particular for identity and parental testing in DNA forensics.
Haixu Tang, Etienne Nzabarushimana
doaj +1 more source
Global abundance of short tandem repeats is non-random in rodents and primates
BMC Genomic Data, 2022 Background While of predominant abundance across vertebrate genomes and significant biological implications, the relevance of short tandem repeats (STRs) (also known as microsatellites) to speciation remains largely elusive and attributed to random ...
Masoud Arabfard +6 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Partitional clustering algorithms for highly similar and sparseness Y-Short Tandem Repeat Data / Ali Seman [PDF]
, 2013 Clustering is an overlapping method found in many areas such as data mining, machine learning, pattern recognition, bioinformatics and information retrieval.
Seman, Ali
core
Molecular cytogenetic characterisation of Salix viminalis L. using repetitive DNA sequences [PDF]
, 2013 Salix viminalis L. (2n=38) is a diploid dicot species belonging to the Salix genus of the Salicaceae family. This short-rotation woody crop is one of the most important renewable bioenergy resources worldwide.
Dudits, Dénes +3 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Database of exact tandem repeats in the Zebrafish genome
BMC Genomics, 2010 Background Sequencing of the approximately 1.7 billion bases of the zebrafish genome is currently underway. To date, few high resolution genetic maps exist for the zebrafish genome, based mainly on single nucleotide polymorphisms (SNPs) and short ...
Rouchka Eric C
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Forensic Autosomal Short Tandem Repeats and Their Potential Association With Phenotype
Frontiers in Genetics, 2020 Forensic DNA profiling utilizes autosomal short tandem repeat (STR) markers to establish identity of missing persons, confirm familial relations, and link persons of interest to crime scenes.
Nicole Wyner +3 more
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Protein Repeats from First Principles [PDF]
, 2016 Some natural proteins display recurrent structural patterns. Despite being highly similar at the tertiary structure level, repeating patterns within a single repeat protein can be extremely variable at the sequence level. We use a mathematical definition
Becher, Veronica Andrea +4 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source