Results 141 to 150 of about 182,546 (363)

Mechanical Stress Triggers Premature Senescence in Cardiac Fibroblasts

open access: yesAdvanced Science, EarlyView.
Cellular senescence contributes to disease burden in cardiovascular disease (CVD) and aging, highlighting the need to understand its induction. In primary cardiac fibroblasts, reduced strain and increased frequency, mimicking CVD, elicit a distinct senescent phenotype compared to oxidative stress.
Stephanie E. Schneider   +5 more
wiley   +1 more source

Protective efficiency and immune responses to single and booster doses of formalin-inactivated scale drop disease virus (SDDV) vaccine in Asian seabass (Lates calcarifer)

open access: yesBMC Veterinary Research
Background Scale drop disease virus (SDDV) threatens Asian seabass (Lates calcarifer) aquaculture production by causing scale drop disease (SDD) in Asian seabass.
Putita Chokmangmeepisarn   +6 more
doaj   +1 more source

Understanding the role of the shrimp gut microbiome in health and disease.

open access: yesJournal of Invertebrate Pathology, 2020
C. Holt   +3 more
semanticscholar   +1 more source

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du   +5 more
wiley   +1 more source

Novel Bioresorbable Bone Wax for Potentiated Hemostasis and Osteogenesis

open access: yesAdvanced Science, EarlyView.
The synthesized bioresorbable bone wax material for hemostasis and osteogenesis. The preparation process of the novel resorbable bone wax and its mechanism of accelerating coagulation and promoting osteoregeneration through blood cell aggregation. Abstract Orthopedic surgery faces dual challenges of uncontrolled bleeding and poor bone regeneration at ...
Longbao   +10 more
wiley   +1 more source

Reinstating Niche Failure in Diabetic Cranial Defects via Chronotaxic Signal‐Amplifying Fluidic Biomimetic Hydrogel

open access: yesAdvanced Science, EarlyView.
An in situ moldable GelSSO/PDA@SDF hydrogel functions as a chronotaxic signal‐amplifying biomimetic niche to restore regenerative failure in diabetic cranial defects. By sequentially releasing SDF‐1α‐loaded PDA nanoparticles and osteoinductive oligodeoxynucleotides, it orchestrates immunomodulation, progenitor recruitment, angiogenesis, and ...
Yingji Mao   +5 more
wiley   +1 more source

Dietary lacto-sacc stimulates the immune response of gravid mud crab (Scylla olivacea)

open access: yesComparative Immunology Reports
Mud crabs have a functioning innate immune system. Probiotics have a considerable effect in improving immune responses in gravid mud crab. The current study investigated the influence of three lacto-sacc concentrations (T1=0 %, T2=1 %, and T3=1.5 %) in a
Md. Abdul Hannan   +7 more
doaj   +1 more source

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