Results 1 to 10 of about 116,138 (312)

Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus [PDF]

, 2014
: Several bacterial pathogens decorate their surfaces with sialic acid (Sia) residues within cell wall components or capsular exopolysaccharides. Sialic acid expression can promote bacterial virulence by blocking complement activation or by engagement of
Aaron Louie, AC Kuyl van der, AF Carlin, Ajit Varki, AL Lewis, AP Heikema, B Khatua, C Jones, C Liu, C Oetke, CE Rubens, E Vimr, ER Eichner, G Bao, G Kraal, G Kraal, H Cao, H Rempel, JM Haan den, Joshua Olson, JP Pereira, K Asano, L Martinez-Pomares, M Cornelissen, M Klaas, MB Marques, MR Wessels, MR York, N Vanderheijden, P Aichele, P Barral, P Seiler, Paul R. Crocker, PR Crocker, R Biesen, RE Mebius, RN Davidson, S Hannedouche, S Ram, S Weiman, T Junt, VG Monteiro, Victor Nizet, YS Xiong, Yung-Chi Chang, Z Zou   +45 more
core   +3 more sources

Relationship between dietary sialic acid intake and serum HbA1c: a population-based study in Xiamen, China

Scientific Reports
This study investigates the correlation between dietary sialic acid intake which mainly come from eggs, red meat, and dairy products and serum HbA1c levels. A survey among Xiamen’s general population, China, collected dietary data from 2,908 participants
Zecheng Zhou, Wei Zhang, Xinyue Wang, Wanqiu Sha, Zhikun Xu, Hongwei Li, Jiale Huang   +6 more
doaj   +1 more source

Serum Total and Lipid Bound Sialic Acid Levels in Patients With Benign and Nonmelanom Malignant Skin Tumors [PDF]

Türk Biyokimya Dergisi, 2007
It has been reported that sialic acid containing oligosaccharides play an important rolein the adhesion between cancer cells and endothelial cells and metastatic potential of tumorcells is proportional to cell surface sialylation.
Beyhan Çakır, Cemal Aygıt, 1Bendigar Sunar, Selma Süer Gökmen,, Cemal Kazezoğlu,   +4 more
doaj  

Studying Lactoferrin N-Glycosylation. [PDF]

, 2017
Lactoferrin is a multifunctional glycoprotein found in the milk of most mammals. In addition to its well-known role of binding iron, lactoferrin carries many important biological functions, including the promotion of cell proliferation and ...
Barile, Daniela, German, J Bruce, Karav, Sercan, Le Parc, Annabelle, Rouquié, Camille   +4 more
core   +3 more sources

Absence of Neu5Gc and Presence of Anti-Neu5Gc Antibodies in Humans-An Evolutionary Perspective. [PDF]

, 2019
The glycocalyx of human cells differs from that of many other mammals by the lack of the sialic acid N-glycolylneuraminic acid (Neu5Gc) and increased abundance of its precursor N-acetylneuraminic acid (Neu5Ac).
Altman, Meghan O, Gagneux, Pascal
core   +1 more source

Glycan analysis of the chicken synaptic plasma membrane glycoproteins - a major synaptic N-glycan carries the LewisX determinant [PDF]

, 2005
The majority of plasma membrane components are glycosylated. It is now widely accepted that this post-translational modification is crucial during the establishment, maintenance and function of the nervous system.
Koles, Kate, McDowell, William, Mileusnic, Radmila, Rose, Steven P.R.   +3 more
core   +4 more sources

Diagnostic Value of Sialic Acid in Pleural Effusion

Chinese Journal of Lung Cancer, 2010
The present study was conducted in 30 patients of malignant pleural effusion and 30 patients of non malignant pleural effusion. Pleural fluid and blood samples were taken at the time of admission, before starting any treatment.
S KHARB, S TANDON, A BANSAL
doaj  

Genome-wide CRISPR screen reveals key role of sialic acids in PEDV and porcine coronavirus infections

mBio
Porcine epidemic diarrhea virus (PEDV) is a globally distributed alphacoronavirus with economic importance that can cause severe watery diarrhea and even death in piglets.
Guanghao Guo, Mengjia Zhang, Zhuojia Xu, Peng Xi, Hongmei Zhu, Anouk Evers, Robert Jan Lebbink, Yifei Lang, Qigai He, Yao-Wei Huang, Tiehai Li, Berend Jan Bosch, Wentao Li   +12 more
doaj   +1 more source

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection

, 2018
Autoreactive B cells have a central role in the pathogenesis of rheumatoid arthritis (RA), and recent findings have proposed that anti-citrullinated protein autoantibodies (ACPA) may be directly pathogenic.
Amara, Khaled, Baeten, Dominique, Gabay, Cem, Gronwall, Caroline, Israelsson, Lena, Klareskog, Lars, Lanzavecchia, Antonio, Lloyd, Katy A., Lundberg, Karin, Lundstrom, Susanna L., Malmstrom, Vivianne, Mueller, Daniel L., Piccoli, Luca, Reed, Evan, Steen, Johanna, Titcombe, Philip J., Zhou, Diana, Zubarev, Roman A.   +17 more
core   +2 more sources

Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies [PDF]

, 1993
In biological fluids, hCG and its free alpha- (hCG alpha) and beta-subunits (hCG beta), occur in multiple forms. These various forms differ at the molecular level primarily in glycosylation, but also differ in protein backbone modifications corresponding
Berger, Peter, Mann, Klaus, Schwarz, Siegfried, Spöttl, Gerald, Wick, Georg   +4 more
core   +1 more source