Results 11 to 20 of about 2,579,458 (259)

Characterization of sialate-O-acetylesterases in the gut commensal bacterium Bacteroides thetaiotamicron [PDF]

, 2013
The sialic acids are a family of acid sugars that are widely distributed in mammal cells and are found typically linked to the distal end of glycan chains in mammalian glycoproteins, including the mucin proteins found on mucosal surfaces. The most common
Nadat, Fatima
core   +6 more sources

Structural studies and functional engineering of NanX: an anhydro-sialic acid transporter from Escherichia coli. [PDF]

FEBS Open Bio
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Newton-Vesty MC, Hall KR, Tillett ZD, Turk LS, Davies JS, Currie MJ, Brown HG, Valimehr S, Mace PD, Whitten AE, Panjikar S, Hanssen E, North RA, Dobson RCJ.   +13 more
europepmc   +2 more sources

Sialic acid utilization by Cronobacter sakazakii [PDF]

, 2013
Background: The Cronobacter genus is composed of seven species, and can cause infections in all age groups. Of particular concern is C. sakazakii, as this species is strongly associated with severe and often fatal cases of necrotizing enterocolitis and ...
Forsythe, S, Hariri, S, Stephen Forsythe, Joseph, S, Susan Joseph, Sumyya Hariri, Masood, N, Naqash Masood   +7 more
core   +3 more sources

Sialic Acid Utilization [PDF]

Advances in Nutrition, 2012
Early postnatal development encounters milk as a key environmental variable and yet the sole nutrient source. One evolutionary conserved constituent of milk is sialic acid, which is generally displayed on glycoconjugates and free glycans. During early postnatal development, high sialic acid need was proposed to be unmet by the endogenous sialic acid ...
Norbert, Sprenger, Peter I, Duncan
openaire   +2 more sources

Synthesis of Sialic Acids and Sialic Acid Derivatives [PDF]

, 1982
Sialic acids as such, sialic acid derivatives, analogues, glycosides and sialooligosaccharides have been subject of many synthetic investigations. These studies were aimed at a further exploration of the properties of sialic acids, the preparation of substrates and inhibitors for sialidases, sialyltransferases or for sialic acid converting enzymes, and
Vliegenthart, J.F.G., Kamerling, J.P.
openaire   +2 more sources

Intramolecular Lactones of Sialic Acids [PDF]

International Journal of Molecular Sciences, 2020
The so-called “sialo-chemical-biology” has become an attractive research area, as an increasing number of natural products containing a sialic acid moiety have been shown to play important roles in biological, pathological, and immunological processes.
Rota P., La Rocca P., Allevi P., Pappone C., Anastasia L.   +4 more
openaire   +2 more sources

Relationship between plasma sialic acid and fibinogen concentration and incident micro-and macrovascular complications in type 1 diabetes [PDF]

, 2008
AIMS/HYPOTHESIS: Type 1 diabetes is associated with an increased risk of vascular complications. This increased risk could be explained by sialic acid and/or fibrinogen.
MICCOLI, ROBERTO, Pickup, J C, SOEDAMAH MUTHU SS, S. S. Soedamah-Muthu, J. H. Fuller, Chaturvedi, N, On behalf of EURODIAB PCS STUDY GROUP, CHATURVEDI N, Pickup, J.C., Fuller, J.H., Fuller, J H, FULLER JH, N. Chaturvedi, null null, PICKUP JC, J. C. Pickup, Soedamah-Muthu, S.S., Soedamah-Muthu, S S, Chaturvedi, N.   +18 more
core   +1 more source

Sialic acids in gastropods [PDF]

FEBS Letters, 2001
The occurrence of N‐acetylneuraminic acid and N‐glycolylneuraminic acid residues in preparations of the slug Arion lusitanicus (Gastropoda) was determined by sodium dodecyl sulphate electrophoresis of the proteins followed by lectin blots stained with the sialic acid specific lectin from Maackia amurensis, by the sensitivity of this binding to ...
Bürgmayr, Sabine, Grabher-Meier, Heidi, Staudacher, Erika   +2 more
openaire   +2 more sources

Facile Anomer-oriented Syntheses of 4-Methylumbelliferyl Sialic Acid Glycosides [PDF]

, 2021
As part of a program to find new sialidases and determine their enzymatic specificity and catalytic activity, a library of 4-methylumbelliferyl sialic acid glycosides derivatised at the C-5 position were prepared from N-acetylneuraminic acid.
Stefan, Oscarson, Abdullah, Hassan
core   +2 more sources

Multivalent sialic acid binding proteins as novel therapeutics for influenza and parainfluenza infection [PDF]

, 2014
In nature, proteins with weak binding affinity often use a multivalency approach to enhance protein affinity via an avidity effect. Interested in this multivalency approach, we have isolated a carbohydrate binding module (CBM) that recognises sialic ...
Alias, Nadiawati
core   +2 more sources